This paper reports the nursing care for an elderly patient with stiff person syndrome accompanied with multiple myeloma,which focused on pain management,prevention of muscle spasm,psychological care,close observation of patients' condition,medication monitoring and guidance of functional exercises.After 58 days of careful treatment and nursing care,the patient was discharged from the hospital.

Objective To investigate four methods for establishing animal models of human breast cancer bone metastasis. Methods Thirty-two female nude mice aged 4-6 weeks were divided randomly into four groups (n=8 in each group). 5×105 MDA-MB-231 cells were injected into the body via the left second mammary fat pads (group A), the tail veins (group B), the left heart ventricles (group C) and the left tibia marrow cavities (group D), respectively. Tumor formations in situ were recorded in group A. Deaths after the injection were recorded. The surviving nude mice 49 days after the injection were subjected to pathological examination to determine bone metastasis. Results The rate of tumor formation in situ of group A was87.5 %(7/8). One mouse in group C died after the injection of MDA-MB-231 cells. The bone metastasis rate in groups A, B, C and D was zero (0/8), 12.5 % (1/8), 71.4 % (5/7) and 100 % (8/8), respectively. There was statistically significant difference in the bone metastasis rate between group A and group C, group A and group D, group B and group C; and group B and group D. Conclusion Injections of tumor cells via the breast fat pads and tail veins were not suitablemethods to establish animal models of human breast cancer bone metastasis. The bone metastasis model could be established efficiently by injecting tumor cells into the left heart ventricles or the bone marrow cavity of nude mice.

Objective To establish two grade triage safety management mode in outpatient department,and to evaluate its effects of application for outpatient nursing quality management.Methods Two grade triage safety management mode was established:improving management system for two grade triage,establishing nursing position for two grade triage,improving patient triage management software and triage management scheme.The convenience sampling method was adopted to extract the two grade triage safety management model.Satisfaction of outpatients,nursing risk warning evaluation and nursing safety management were evaluated before and after the implementation of two grade triage safety management mode.Results After the implementation of two grade triage safety management mode in outpatient department,the overall satisfaction of outpatients was improved from (4.00±0.89) points to (4.67±0.37) points (P＜0.05).The overall compliance rate of nursing risk warning evaluation index showed significant increases (P＜0.05),and the qualification rate of rescue items was increased from 84.55％ to 95.91％ after the implementation.For nursing safety management program,the utilization rate of prior passages was increased from 5.22％ to 20.45％.The usage rate of self-service blood pressure measurement was increased from 1.94％ to 54.33％.The identification rate of high-risk fall patients was increased from 13.82％ to 43.36％.All differences were statistically significant (P＜0.05).Conclusion The implementation of two grade triage safety management mode is helpful to improve satisfaction of outpatients,and promote outpatient safety quality management.

The authors introduced the development and application of an outpatient triage safety management system for hospitals. The system consists of the triage queue module, fast track module for prioritized special outpatients and subsequent outpatients, vital signs data recording module, assessment module for high fall risk outpatients, and high risk outpatient transfer module. These functions enable outpatient triage nurses to focus on pre-examination, safety factor identification, and high risk outpatient transfer, thus shortening outpatient queue time and high risk outpatient transfer to emergency, and lower adverse events. With this system, nursing safety management becomes more scientific, standardized and systematic, enabling optimized nursing staff efficiency and fine management of nursing care.