1.Visualization analysis on international medical device study based on CiteSpace
Mingyin JIANG ; Shenglin LIU ; Ju CHENG ; Qingmin FENG ; Jianyang ZHANG ; Jiaqi GAO ; Qiang ZHANG
Chinese Medical Equipment Journal 2017;38(3):38-42
Objective To analyze the history and present situation of international medical device with visualization softwareto provide references for medical device development in China.Methods CiteSpace visualization software was used to explore international literatures related to medical device from the aspects of yearly quantity,research direction,research organization,quoted literature and etc from 2005 to 2014.Results Medical device drew increasing attention from corresponding researchers,whose development depended on international cooperation.Medical device related closely to engineering and medicine,and had to paid attention to informatization and clinical requirements.Conclusion CiteSpace software is of great value for the study on medical device.
2.Studies on storage technique of Moschus
Chonghua GUO ; Damin WANG ; Li FAN ; Mingyun LI ; Donglin LI ; Xiongzhi GAO ; Baoke FENG ; Qingmin CHEN ;
Chinese Traditional and Herbal Drugs 1994;0(08):-
3.Dietary patterns and thyroid cancer: a case-control studyin Hangzhou residents
REN Yanjun ; ZHANG Tiewei ; LIU Qingmin ; ZHAO Gang ; LU Feng ; GONG Weiwei ; YU Min
Journal of Preventive Medicine 2020;32(11):1081-1085
Objective :
To learn the association between dietary patterns and thyroid cancer in Hangzhou residents, and to provide evidence for thyroid cancer prevention.
Methods:
The newly diagnosed patients with thyroid cancer in Zhejiang Cancer Hospital were selected as the case group, while the healthy population matched (1∶1) by gender, age and residence were selected from community as the control group. A questionnaire survey was conducted to obtain demographic characteristics, disease history, dietary intake, lifestyle and other information. The dietary patterns were established by factor analysis. The multivariate conditional logistic regression model was conducted to explore the relationship between different dietary patterns and thyroid cancer.
Results:
A total of 258 pairs of cases and controls were recruited. Five dietary patterns were obtained, including vegetarian pattern, high-protein food pattern, salted vegetables and algae pattern, seafood and cereal pattern, as well as alcohol and tea pattern. The multivariate conditional logistic regression analysis suggested seafood and cereal pattern might reduce the risk of thyroid cancer (OR=0.286, 95%CI: 0.146-0.561).
Conclusion
More consumption of seafood and cereal may decrease the incidence of thyroid cancer.
4.Economic evaluation of linear accelerator radiation therapy for patients with malignant tumors at hospitals in China
Pengqian FANG ; Qingmin FENG ; Chunyan ZI ; Qiang ZHANG
Chinese Journal of Hospital Administration 2019;35(7):562-565
Objective To make a cost-effectiveness analysis for stereotactic radiotherapy and intensity-modulated radiotherapy using linear accelerators against malignant tumors, then to provide references for choosing a more cost-effective radiotherapy for the patient. Methods Basic information of patients subject to radiotherapy(gender, age, date of admission, days of hospital stay), hospitalization cost, admission diagnosis, clinical outcomes among others of 320 patients with malignant tumors(lung tumor, head and neck tumor, bone metastases, liver tumor) were collected from Hubei, Guangxi and Fujian provinces. The cost of hospitalized radiotherapy and treatment effect of these patients were compared to identify the more cost effective of the two methods. Results The effective rates of stereotactic radiotherapy and intensity-modulated radiotherapy were 99.1% (108/109) and 97.2% (205/211) respectively, and the difference was not significant( P>0.05). The average hospitalization cost of treatment of the two groups was 37 545.56 yuan and 48 159.05 yuan respectively; the cost-effectiveness ratio was 37 886.54 and 49 546.35 respectively. Conclusions The short-term effects of stereotactic and intensity-modulated radiotherapy are similar, but the cost of intensity-modulated radiotherapy is higher. The minimum cost analysis shows that stereotactic radiotherapy is more cost effective.
5.The Nomogram model in predicting prognosis of hepatocellular carcinoma patients based on four inflammatory markers
Zhiqiang FENG ; Zixuan YANG ; Shanshan HAN ; Yutao SHANG ; Junhui ZHAO ; Wanqing GU ; Qingmin YANG ; Jieying WU ; Jun SHENG ; Xiaodong GUO
Chinese Journal of Hepatobiliary Surgery 2020;26(6):443-448
Objective:To construct a Nomogram model in predicting recurrence-free survival (RFS) and overall survival (OS) at six months, one year and two years after hepatocellular carcinoma (HCC) resection by using inflammatory markers combined with other routine clinical indicators.Methods:The data of 314 patients with HCC who underwent first time hepatectomy at Beijing Chaoyang Emergency Rescue Center and Air Force Characteristic Medical Center from January 2013 to January 2018 were analyzed. HCC patients who underwent hepatectomy at the First Medical Center of PLA General Hospital from January 2011 to January 2016 ( n=106) were used as the external validation group. Univariate and multivariate Cox proportional risk model was used to analyze independent risk factors of recurrence and death in HCC patients. A Nomogram model was constructed based on independent risk factors. Validation of the efficacy of the Nomogram model was done based on external data. Results:In the experimental group, 174 patients relapsed. The median RFS was 26 months. The 6 months, 1 year and 2 years RFS were 26.8%, 43.9%, and 68.8%, respectively. A total of 142 patients had died. The median survival time was 30 months. The 6 months, 1 year and 2 years OS were 5.9%, 23.6% and 63.1%, respectively. In the external validation group, 63 patients had developed recurrence, with a median RFS time of 28 months. The 6 months, 1 year and 2 years RFS were 26.4%, 45.3%, 54.7%, respectively. The median survival time was 31 months. The 6 months, 1 year and 2 years OS were 7.5%, 25.5%, 46.6%, respectively. Tumor size (>6.0 cm, HR: 1.447), vascular invasion ( HR: 1.408), TBil (>0.94 mg/dl, HR: 1.949), NLR (>2.54, HR: 2.843), AGR (≤0.88, HR: 2.447) were independent risk factors of HCC recurrence ( P<0.05). Tumor size (>6.0 cm, HR: 2.207), vascular invasion ( HR: 1.529), and NLR (>2.54, HR: 2.708) were independent risk factors of death for HCC patients ( P<0.05). The C-indexes of half-year, one-year and two-year RFS were 0.764 (95% CI: 0.677-0.854), 0.710 (95% CI: 0.615-0.824) and 0.673 (95% CI: 0.601-0.786), respectively. The C-indexes of half-year OS, one-year OS and two-year OS were 0.729 (95% CI: 0.648-0.841), 0.708 (95% CI: 0.608-0.813) and 0.664 (95% CI: 0.618-0.771), respectively. Conclusion:In this study, the construction of a Nomogram model in predicting prognosis of HCC patients was helpful to guide clinicians in improving preoperative treatment plans and in providing ideas for individualized treatment of patients.
6.Risk Analysis of Radiotherapy Implementation Process Based on Failure Mode and Effect Analysis.
Mingyin JIANG ; Linlin WANG ; Jiaqi GAO ; Mengya HU ; Qin LI ; Zhenjun PENG ; Qingmin FENG ; Xutian ZHANG ; Qiang ZHANG ; Shenglin LIU
Chinese Journal of Medical Instrumentation 2019;43(3):230-234
OBJECTIVE:
Providing a risk assessment method for the implementation of radiotherapy to identify possible risks in the implementation of the treatment process, and proposing measures to reduce or prevent these risks.
METHODS:
A multidisciplinary expert evaluation team was developed and the radiotherapy treatment process flow was drawn. Through the expert team, the failure mode analysis is carried out in each step of the flow chart. The results were summarized and the (risk priority ordinal) score was obtained, and the quantitative evaluation results of the whole process risk were obtained.
RESULTS:
One hundred and six failure modes were obtained, risk assessment of (20%) high risk failure model are 22 and severity (≥ 8) high risk failure model are 27. The reasons for the failures were man-made errors or hardware and software failures.
CONCLUSIONS
Failure mode and effect analysis can be used to evaluate the risk assessment of radiotherapy, and it provides a new solution for risk control in radiotherapy field.
Healthcare Failure Mode and Effect Analysis
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Risk Assessment