1.Training of applied IOT engineering personnel in medical colleges and universities
Chinese Journal of Medical Library and Information Science 2015;(6):71-74
IOT engineering in medical colleges and universities is of its universality and its particularity compared with other kinds of colleges and universities .The strategies of working out the training plan for students of IOT engi-neering in medical colleges and universities were studied from the aspects of implementation of excellent plan, wis-dom medical care, and211 quality project.The requirements of knowledge and ability for students of IOT engi-neering were put forward .The students were trained in practical teaching by renewing the education concepts , re-forming the course teaching, strengthening the practical ability, and attaching importance to scientific and technical innovation .
2.The status and strategy of high level Chinese Medicine Talents training in China since 1949
Chinese Journal of Medical Education Research 2011;10(11):1311-1314
The training model of high level Chinese Medicine Talents has been the focus of debate in Chinese Medicine over the years.Through reviewing the history of high level Chinese Medicine Talents training in China since 1949,we have summarized the characteristics and analyzed the deep level problems impacting the quality of talents training.The strategies which we have proposed in this study will have high significance not only in the theory but in a realistic sense.
3.A qualitative research on the elderly care needs of older residents living in residential care facilities
Longhua TANG ; Qingling ZHONG ; Xiwen LI
Chinese Journal of Practical Nursing 2015;31(21):1622-1625
Objective To describe the elderly care needs of older residents living in residential care facilities in Nanchang.Methods Three residential care facilities were purposefully selected and 19 residents were interviewed.The datum were tape-recorded,transcribed in full and then analyzed to identify the main patterns of responses.Results The elderly care needs of older residents in residential care facilities were generated four themes including the body,environment,mind,preparation for death.Conclusions China should establish endowment institutions endowment service needs assessment index system,improve the system of pension agency grading nursing.Enhance communication between pension institutions and medical institutions,to meet the demand for skilled nursing skills in the old man.Carrot and stick,reasonable allocation of resources,physical and social environment of hoisting mechanism,to meet the old man's psychological demand and the demand for environment.Enhancement of the humanistic care of dying old man,to meet the needs of stay in the old man to the hospice.
4.Preliminary study on mobile platform-oriented echocardiogram data visualization for the evaluation of left ventricular diastolic function
Qingling ZHANG ; Xiangming ZHU ; Guojie LI
Chinese Journal of Ultrasonography 2013;22(9):813-816
Objective To research and develop the mobile platform-oriented echocardiogram data visualization technology for the evaluation of left ventricular diastolic function,and investigate its application value.Methods First,diagnostic algorithms for the evaluation of left ventricular diastolic function (based on recommendations from ASE & EAE guidelines) were programmed into a mobile application software package,using Adobe Flex builder 4.0 as a basic tool for data visualization.Second,the program was installed in the Apple iPad4 tablet computer,then debugged and improved according to feedback information from practical applications.Results The echocardiogram data visualization for the estimation of left ventricular filling pressures in patients with depressed ejection fraction(EF) or normal EF and grading diastolic function can be implemented in mobile platform device,and simultaneously with emergency bedside echocardiography.The evaluation process can be visually presented by using the graphics to show the algorithm framework,the animation to express the analysis step,the axis to indicate the direction of information,and the color to differentiate the degree of the diastolic dysfunction.Conclusions The mobile platform-oriented echocardiogram data visualization technology makes the evaluation of left ventricular diastolic function more convenient,efficient and fast,and shows its potential to become an important adjunct to evaluation of cardiac function in the context of mobile health.
5.Observation and Nursing to Hepatic Malignancy Patients Treated by Radio Frequency
Shuirong LI ; Qingling YANG ; Suang CAI
Chinese Journal of Practical Nursing 2001;17(3):6-7
Treating Hepatic Malignancies with radio- frequency is a new microinvasive method which has been developed in recent years. The patients treated with this method felt less painfull and recover quickly after operation. The author has reported the detailed observaticn to 39 patients with hepatic carcinomas and cooperated with the doctors for patients'psychological nursing in this article. During the treatment,the author tried to explain the aim,method and treating effect of the operation, help the patients to relieve nervousness end worries, observe the patients' inoperative response under cardiopneumograph and guide the patients for the postoperative observation of complications so that the treatment was completed successfully. The author suggests that sentimental support is an important step in the whole course of nursing
6.Late results of bioprosthesis replacement
Jiyong LI ; Jianqun ZHANG ; Qingling JING
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(06):-
Objective: To evaluate the long-term result after bioprosthesis replacement, and analyse the risk factors of the late deaths. Methods: From September 1984 to March 1988, 90 patients underwent bioprosthesis replacement in our hospital. There were 39 males (43%) and 51 females (57%) with an average age of 36.1 years. 78 patients had rheumatic disease, 8 degenerative disease, 3 congenital mitral valve anomaly and 1 Ebstein's anomaly. The preoperatively heart function (NYHA) was grade II in 15, grade III in 54, and grade IV in 21. C/T was 0.51~0.90 (average 0.65?0.10). Results: The operative mortality rate was 7。8%. All survived patients were followed up. The mean follow-up time was 7.8 years (range from 3 months to 15.7 years. 35 patients died during the follow-up period. The causes of death cardiac related deaths in 33 patients (88.6%), noncardiac related death in 3 (8.6%), and unknown in 1 (2.8%). Reoperation was performed in 20patients. At 1, 5 and 10 years after operation, the actuarial survival rate of patients were 92.7%, 80.7% and 57.8%, respectively. Multiple regression analysis showed that preoperatively cardiac function, C/T ratio and EF were risk factors for late deaths. Conclusion: The long-term results with bioprosthesis replacement appear satisfactory.
7.Expression of Fas/FasL and their significance in the pathological tissues of SARS patients
Li HE ; Qingling ZHANG ; Yanqing DING
Chinese Journal of Practical Internal Medicine 2001;0(04):-
Objective To study the mechanisms and expressions of Fas/FasL in the lungs,spleens and lymph nodes of SARS patients.Methods The lungs,spleens and lymph nodes specimens of four autopsy cases and one control subject were studied with immunohistochemical mehod.Results Compared with normal tissues,apoptotic cells increased significantly in the spleens,lungs and lymph nodes of SARS patients.The apoptotic cells of lungs included alveolar epithelial ones,bronchial epithelial ones,monocytes/macrophages and lymphocytes.Apoptosis in the spleens and the lymph nodes was observed primarily in monocytes/macrophages and lymphocytes.Conclusion Over-expression of Fas/FasL is a general phenomenon in SARS,suggesting that Fas/FasL may play a key role in the pathogenesis of SARS.
8.Extend-spectrum ?-latamases strains: methods and resistance
Shanhua PENG ; Congrong LI ; Qingling SHI
Chinese Journal of Laboratory Medicine 2000;0(06):-
Objective To compare three methods for detecting extend-spectrum ?-latamases (ESBL s) and investigate current resistance of ESBL s.Methods 538 isolates of Enterobacter were detected by VITEK-AMS, compound piece type confirm test, and double-disk synergy test.Results 20.1% (108/538) was found to be ESBL s positive by VITCK-AMS. The positive rate of ceftaxime/clavulanic acid and ceftaxime compound pieces test was 19.5% (105/538). The positive rate of double-disk synergy test was 13.0%. The resistant rate of 12 antibiotics to ESBL s positive strains was significantly higher than ESBL s negative strains.Conclusions It is important to select the proper and rapid method to detect ESBL s in time.
9.Process study of brain protein hydrolysate of inactivate and virus removal
Fengxia LI ; Yunhai CHU ; Qingling HUANG ; Hongwei LI
Chinese Journal of Primary Medicine and Pharmacy 2015;22(1):54-56
Objective To study the process of brain protein hydrolysate of inactivate and virus removal.Methods The Parvoviridae parvovirus genera of porcine parvovirus (PPV),vesicular stomatitis virus rhabdovirus genera of vesicular stomatitis virus (VSV) were chosen as a model virus,wherein PPV represents no envelope deoxyribonucleic acid(DNA) virus,VSV represents the envelope ribonucleic acid(RNA) virus.Simulation of the production process of virus inactivation steps 100 ℃ × 30 min,ultrafiltration as inactivation/removal condition.The virus respectively according to 1 ∶ 9 into the brain protein hydrolysate,high temperature and ultra filtration virus inactivation/removal.In pig kidney cells (PK-15) in PPV cell culture,Africa green monkey kidney cells(Vero cells) cultured VSV,determination of virus titer.Results PPV and VSV through the sterilization,virus median tissue culture infective dose(TCID50) were 6.15log/0.1mL(logs),5.37 log/0.1mL(logs) ;removal processaverage virus reduction coefficient were 6.15log/0.1mL(logs),5.37 log/0.1mL(logs).Conclusion The high temperature and ultra filtration produces brain protein hydrolysate solution process are effective virus inactivation/removal process.
10.Expression of p27 in Rectal Carcinoma and Modulatory Relation Between Transforming Growth Factor-?1 and p27
Changqing JING ; Leping LI ; Zhao LI ; Taihuang WU ; Qingling MU ;
Chinese Journal of Bases and Clinics in General Surgery 2004;0(01):-
Objective To detect p27 expression in rectal carcinoma and serum transforming growth factor ? 1 (TGF ? 1) level in these patients, and to elucidate the modulatory effect of serum TGF ?1 on p27 expression in rectal carcinoma. Methods Expression of p27 was measured in 37 cases of rectal carcinoma, 22 of rectal adenoma and 19 of normal control specimens by immunohistochemical staining using antibodies to p27. Serum level of TGF ?1 was measured in these patients by enzyme linked immunosorbent assay (ELISA) method. Results p27 protein was expressed in normal rectal tissue, rectal adenoma and rectal carcinoma, and the positive rate was 89.47%, 90.91% and 64.87%, respectively. The positive rate of p27 in rectal carcinoma was significantly lower than that of normal rectal tissue and rectal adenoma ( P =0.025). p27 was mainly located in nucleolus of normal rectal tissue and rectal adenoma, and the positive rate of p27 in cytoplasm of rectal carcinoma was higher than that of normal and rectal adenoma. The positives rates of serum TGF ?1 in normal group, rectal adenoma group and rectal carcinoma group were 21.05%, 27.27% and 51.35%( P =0.045),respectively. The expression of p27 related to histological differentiation, lymph node metastasis and infiltration depth. Serum level of TGF ?1 related to lymph node metastasis, infiltrated depth and CEA level. The positive rate of p27 in TGF ?1 negative group and positive group was 88.89% and 42.11%(Mantel Haenszel ? 2=6.755, P =0.009), respectively. Conclusion TGF ?1 may be useful in assessment of malignance and prognosis of rectal carcinoma. TGF ?1 can down regulate p27 expression in rectal carcinoma.