1.The contrast of clinical efficacy of two different guide wire in endoscopic retrograde cholangiopancreatography
Chinese Journal of Postgraduates of Medicine 2012;(34):26-28
Objective To observe the comparison of two different guide wire in endoscopic retrograde cholangiopancreatography (ERCP).Methods One hundred and twenty-four patients who were identified with ERCP indications were divided into the loach guide wire group (group A) and zebra guide wire group (group B) by random digits table,each with 62 cases.Intubation time,rate of successful intubation and postoperative complication was compared.Results The rate of of one-time successful intubation in group A was 95.2%(59/62),significantly higher than that in group B [82.3%(51/62)] (P <0.05).The average time of one-time successful intubation in group A was (1.38 ± 0.52) min,significantly lower than that in group B [(1.63 ± 0.61) min] (P < 0.05).The rate of total successful intubation in group A was 95.2%(59/62),in group B was 96.8%(60/62),there was no significant difference (P> 0.05).The rate of postoperative hyperamylasemia and pancreatitis in group A was 12.9% (8/62),in group B was 32.3% (20/62),there was significant difference (P < 0.05).Conclusion The application of the loach guide wire in ERCP operation is significantly better than that of the zebra guide.
2.Application of low seniority nurses safety training in health-safety-environment management system
Ailing QIN ; Hong QU ; Qingli WANG ; Feifan WANG ; Mingjuan DU
Chinese Journal of Practical Nursing 2015;(31):2407-2410
Objective To explore the effective nursing and long-term safety training mode, early intervention on safety awareness of junior nurses, regulate the safety behavior, ensure patient safety. Methods The ideas and methods of HSE management system (health, safety and environment trinity management system) were introduced, from training needs research, safety courses design, safety behavior training, training process management,safety knowledge clinical application and training quality control implementation of systematic management.From 2013 to 2014 low seniority nurses safety training for 2 years, including new hospital nurse per year.Taking the self contrast before and after experimental design, safety knowledge to master the situation, the nurse's satisfaction and quality of care and safety management before and after training were compared. Results The actual class qualified rate and safety knowledge awareness and the excellent and good rate of safety skills assessment after training were 80.10%(157/196), 92.34%(181/196),96.43%(189/196), which were higher than those of 65.30%(128/196), 81.63%(160/196), 88.78%(174/196) before training, and the differences were statistically significant, χ2=10.81,9.94,7.07,P<0.01. The overall satisfaction of the nurses for safety training was 92.35%(181/196)after training, which was higher than that of 80.61%(158/196)before training, the difference was statistically significant, χ2=16.37, P < 0.01.The qualified rate of nursing quality for the critically ill patients after training was 90.13%(210/233), which was higher than that of 81.48%(176/216) before training, the difference was statistically significant, χ2= 6.94, P < 0.01. The patient safety and quality, the quality of nursing records were 95.81%(206/215), 95.29%(688/722) after training, respectively, which were higher than those of 89.60%(181/202), 85.10%(577/678) before training, the differences were significant, χ2=5.98,4.17, P<0.05. Conclusions Improved safety training is normative, practicability and maneuverability, safety behavior norms, improve the risk identification and emergency handling ability, reduce nursing risk, close to the clinical need for safety management, safety training for nurses to provide the basis for sustainable development.
3.Analysis of disease and health risk factors among teachers in one university of Chongqing
Xiaohong YANG ; Shanbi ZHOU ; Youhong XIE ; Qiongwu YU ; Hao LIU ; Zongliang LU ; Yu QIN ; Qingli HE ; Mantian MI
Chongqing Medicine 2014;(25):3325-3328
Objective To understand the teachers′health status of one university in Chongqing to provide the basis for the healthcare of this group.Methods The teachers′health examination information in1 303 cases of physical healthy examination was retrospectively analyzed.The data were analyzed by the SPSS17.0 statistical software.Results The main detected diseases were conj unctivitis,fatty liver,cataract,refractive error,eyeground arteriosclerosis and hypertension.The top-5 health risk factors includ-ed dyslipidemia,overweight,hyperpiesia,increased uric acid and fasting blood glucose abnormality.The detection rates of conj uncti-vitis,fatty liver,eyeground arteriosclerosis,overweight,hyperpiesia,increased uric acid,fasting blood glucose abnormality examined in males were obviously higher than those in females(P<0.05),while which of cataracts,refractive errors,hypertension and dyslip-idimia were not relevant to gender(P>0.05).Apart from the increased uric acid(P=0.740),the morbidity and risk factors in dif-ferent ages were markedly different(P<0.01).The case rate of diabetes and hypertension was lower than the national average. Conclusion The eye health status of teachers in this university is not optimistic;there were many health risk factors.The health knowledge education of overweight,dyslipidemia,pathoglycemia and hyperpiesia should be carried out aiming at this group.
4.Perioperative nursing of holmium laser enucleation of the prostate of 45 patients
Qingli CHEN ; Chao QIN ; Xiaoxin MENG ; Jun TAO ; Changjun YIN
Journal of Clinical Medicine in Practice 2014;(14):64-66
Objective To explore the perioperative nursing of holmium laser enucleation of the prostate (HoLEP).Methods 45 patients with benign prostatic hyperplasia (BPH)and blad-der outlet obstruction (BOO)underwent holmium laser enucleation of the prostate.The nursing focused on psychological care and preoperative preparation,monitoring postoperative vital signs, the bladder flush unobstructed,preventing of lower limb venous thrombosis,telling patients drink water early according to the bowel sounds,postoperative health guidance and discharge guidance. Results 45 patients who underwent HoLEP had no complications,less postoperative bleeding and discharged from hospital successfully.Conclusion Preoperative psychological nursing for patients with hyperplasia of prostate,preoperative preparation,assisting postoperative bed,monitoring vi-tal signs,guaranteeing the bladder flush unobstructed,taking nursing measures to prevent the vein thrombosis of lower limbs according to DVT score,and skin care,postoperative rehabilitation exer-cise,health guidance and discharge guidance ensure the recovery and discharge from hospital.So it is worthy of promotion.
5.The application and reflection of emerging molecular detection technologies in Salmonella detection
Linlin XIAO ; Yulin LONG ; Xiaojie QIN ; Xiang WANG ; Qingli DONG
Chinese Journal of Preventive Medicine 2024;58(9):1450-1457
Salmonella is an important foodborne pathogen and one of the main causes of diarrhea. Every year, about 550 million people suffer from diarrhea due to Salmonella infection, of which about 230 000 die. It has become a major global public safety issue. The application fields of Salmonella detection involve food safety, water quality monitoring, animal husbandry, public health monitoring, and medical diagnosis. The detection requirements mainly come from three aspects: pathogen identification, serotype identification, drug resistance and virulence identification. In recent years, the detection technology for Salmonella has made rapid progress, especially the emergence and development of emerging molecular detection technologies, providing new perspectives for Salmonella detection in different scenarios. However, due to the diversity of Salmonella serotypes and the complexity of detection scenarios, existing detection technologies still have some pain points (such as long detection time, cumbersome operation steps, low scene adaptability, etc.). This article will elaborate on the application of several emerging molecular detection technologies with distinct characteristics, such as CRISPR Cas technology, digital PCR technology, sequencing technology, and microfluidic technology, in Salmonella detection. It aims to provide a reference for the development and improvement of Salmonella detection technology and the establishment of infection warning and control systems.
6.The application and reflection of emerging molecular detection technologies in Salmonella detection
Linlin XIAO ; Yulin LONG ; Xiaojie QIN ; Xiang WANG ; Qingli DONG
Chinese Journal of Preventive Medicine 2024;58(9):1450-1457
Salmonella is an important foodborne pathogen and one of the main causes of diarrhea. Every year, about 550 million people suffer from diarrhea due to Salmonella infection, of which about 230 000 die. It has become a major global public safety issue. The application fields of Salmonella detection involve food safety, water quality monitoring, animal husbandry, public health monitoring, and medical diagnosis. The detection requirements mainly come from three aspects: pathogen identification, serotype identification, drug resistance and virulence identification. In recent years, the detection technology for Salmonella has made rapid progress, especially the emergence and development of emerging molecular detection technologies, providing new perspectives for Salmonella detection in different scenarios. However, due to the diversity of Salmonella serotypes and the complexity of detection scenarios, existing detection technologies still have some pain points (such as long detection time, cumbersome operation steps, low scene adaptability, etc.). This article will elaborate on the application of several emerging molecular detection technologies with distinct characteristics, such as CRISPR Cas technology, digital PCR technology, sequencing technology, and microfluidic technology, in Salmonella detection. It aims to provide a reference for the development and improvement of Salmonella detection technology and the establishment of infection warning and control systems.
7.Perioperative nursing of holmium laser enucleation of the prostate of 45 patients
Qingli CHEN ; Chao QIN ; Xiaoxin MENG ; Jun TAO ; Changjun YIN
Journal of Clinical Medicine in Practice 2014;(14):64-66
Objective To explore the perioperative nursing of holmium laser enucleation of the prostate (HoLEP).Methods 45 patients with benign prostatic hyperplasia (BPH)and blad-der outlet obstruction (BOO)underwent holmium laser enucleation of the prostate.The nursing focused on psychological care and preoperative preparation,monitoring postoperative vital signs, the bladder flush unobstructed,preventing of lower limb venous thrombosis,telling patients drink water early according to the bowel sounds,postoperative health guidance and discharge guidance. Results 45 patients who underwent HoLEP had no complications,less postoperative bleeding and discharged from hospital successfully.Conclusion Preoperative psychological nursing for patients with hyperplasia of prostate,preoperative preparation,assisting postoperative bed,monitoring vi-tal signs,guaranteeing the bladder flush unobstructed,taking nursing measures to prevent the vein thrombosis of lower limbs according to DVT score,and skin care,postoperative rehabilitation exer-cise,health guidance and discharge guidance ensure the recovery and discharge from hospital.So it is worthy of promotion.
8.Early Efficacy Assessment of Targeted Therapy for Crohn's Disease by Ultrasound
Medical Journal of Peking Union Medical College Hospital 2024;15(1):130-134
Crohn's disease (CD) is a chronic inflammatory bowel disease with complicated pathogenesis and prolonged condition. In recent years, with the development of targeted therapy, biological agents have been widely used in the treatment of CD, which has significantly improved the prognosis of CD patients. If the efficacy evaluation can be carried out at the early stage of targeted therapy, it may help to figure out the patients who can benefit from the treatment and optimize the treatment plan for the ineffective patients in time. In the evaluation of CD activity and efficacy, ultrasound has the advantages of high accuracy, no radiation and high patient acceptance, and therefore has potential clinical application value in the early efficacy evaluation of CD targeted therapy. This article reviews the research progress to provides a reference for optimizing the treatment plan for CD patients.
9.Monitoring of foodborne pathogens in some ready-to-eat fruits and vegetables in Shanghai in 2021
Xiaojie QIN ; Jiaming LI ; Tianmei SUN ; Yangtai LIU ; Xiang WANG ; Zhuosi LI ; Shuo YANG ; Qingli DONG
Shanghai Journal of Preventive Medicine 2023;35(1):42-46
ObjectiveThe contamination of foodborne pathogens in ready-to-eat fruits and vegetables in Shanghai was analyzed to provide a scientific basis for food safety, risk assessment and related supervision. MethodsFrom June to September 2021, a total of 143 batches of12 kinds of ready-to-eat fruits and vegetables such as lettuce, chicory, and cherry tomatoes were collected from farmers’ markets, supermarkets, and e-commerce platforms. The total number of bacterial colonies, Salmonella, Listeria monocytogenes, Staphylococcus aureus, Cronobacter spp. and Shiga toxin-producing Escherichia coli in the samples were tested according to National Food Contamination and Harmfulness Risk Monitoring Manual. ResultsAmong the 143 batches, foodborne pathogens were detected in 68 batches, with a total detection rate of 47.55% (68/143). A total of 79 strains of foodborne pathogens were detected. The detection rate of Staphylococcus aureus was the highest (32.87%, 47/143), followed by Cronobacter spp. (20.98%, 30/143), Salmonella (0.70%, 1/143), Listeria monocytogenes (0.70%, 1/143), Shiga toxin-producing Escherichia coli (0.00%). Furthermore, the detection rate was higher in different ready-to-eat fruits and vegetables: chicory (17.33%), cucumber (17.14%), cherry tomatoes (16.00%), and honeydew melon (15.38%), respectively. Meanwhile, the contamination rate of pathogens in ready-to-eat fruits and vegetables from farmers’ markets, supermarkets, and e-commerce platforms was relatively high. ConclusionReady-to-eat fruits and vegetables in Shanghai are contaminated by foodborne pathogens. The prevention and control of the contamination of post-harvest fruits and vegetables should be strengthened to reduce the risk of foodborne disease outbreaks.