1.Design for pressure detection and control system in medical compartment
Chinese Medical Equipment Journal 2017;38(4):10-12,21
Objective To design a pressure detection and control system in the medical compartment for bio-agent casualty emergency evacuation and en route treatment during responses to biological warfare or terrorist attack.Methods An instrument and a pressure transmitter were used for detection,display and alarm of positive and negative pressures in the medical compartment,and pulse width modulation was involved in to regulate fan speed and then to control the pressure inthe compartment.Results The system proved its ability to evacuate bio-agent casualty and fulminating infectious patient with no pollution to the environment.Conclusion The system realizes on-line monitoring of the filter absorber in the medical compartment,enhances the efficiency and reliability of casualty care and thus gains high military benefits.
2.Effects of Early Treatment with Mouse Nerve Growth Factor on Wound Healing in Aged Patients with Elec-tric Burn
Meng YANG ; Hongzhi WU ; Hongbo SHAO ; Jianke FENG ; Wei WEI ; Lingmin MENG ; Qingfu ZHANG
China Pharmacy 2016;27(35):4941-4943
OBJECTIVE:To explore the effects of early treatment with mouse nerve growth factor on the wound healing in aged patients with electric burn. METHODS:78 elderly patients with electric burn were divided into control group and observation group by random number table method,with 39 cases in each group. Control group was given routine method for electric burn, and observation group was additionally given Mouse nerve growth factor for injection 30 μg dissolved in 2 ml 0.9% Sodium chlo-ride injection within 24 h,im,qd,on the basis of control group. Treatment course of 2 groups lasted for 2 weeks. Clinical effica-cies of 2 groups were compared as well as VAS score before treatment,3,5,7 days after treatment. The survival rate of skin flaps and the rate of wound healing 3,5,7 days after treatment,the recovery of wound scar,the value of wound blood perfusion,the time of complete wound healing and the occurrence of ADR were also compared. RESULTS:The total effective rate of observation group(94.9%)was significantly higher than that of control group(66.7%),with statistical significance(P<0.05). 3,5,7 days after treatment,VAS score of observation group was significantly lower than that of control group,and the survival rate of skin flaps and the rate of wound healing were significantly higher than those of control group,with statistical significance(P<0.05). Af-ter treatment,VSS score of observation group was significantly lower than that of control group,while the value of wound blood perfusion was significantly higher than that of control group;the time of complete wound healing was significantly lower than that of control group,with statistical significance (P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Early treat-ment with mouse nerve growth factor for elderly patients with electric burns can effectively lower the VAS and VSS score,improve the survival rate of skin flaps and the rate of wound healing,increase the value of wound blood perfusion and shorten the time of complete wound healing with good clinical efficacy and safety.
3.Design of an anesthesia and micro-environment information management system in mobile operating room.
Xianwen WANG ; Zhiguo LIU ; Wenchang ZHANG ; Qingfu WU ; Shulin TAN
Journal of Biomedical Engineering 2013;30(4):762-766
We have designed a mobile operating room information management system. The system is composed of a client and a server. A client, consisting of a PC, medical equipments, PLC and sensors, provides the acquisition and processing of anesthesia and micro-environment data. A server is a powerful computer that stores the data of the system. The client gathers the medical device data by using the C/S mode, and analyzes the obtained HL7 messages through the class library call. The client collects the micro-environment information with PLC, and finishes the data reading with the OPC technology. Experiment results showed that the designed system could manage the patient anesthesia and micro-environment information well, and improve the efficiency of the doctors' works and the digital level of the mobile operating room.
Anesthesia
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Anesthesiology
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instrumentation
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Humans
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Medical Records Systems, Computerized
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Mobile Health Units
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Monitoring, Intraoperative
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methods
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Operating Room Information Systems
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Operating Rooms
4.Preliminary analysis of clinically relevant indicators in two patients with mucolipidosis type Ⅲ and their family members
Yaoping HUANG ; Xichao XIA ; Jianyong WU ; Juan CUI ; Junfeng ZHANG ; Yang LIU ; Guochang XU ; Qingfu HU ; Qing WANG ; Rongzhi LIU
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2018;25(6):662-664
Objective To observe the clinical characteristics of 2 patients with mucolipidosis type Ⅲ. Methods Two sibling patients (a sister and a brother) with mucolipidosis type Ⅲ symptoms and other family members were the research objects, and the changes of their features of hand bone imaging, blood indexes [blood glucose, cholesterol, triacylglycerol (TG), total protein (TP), albumin (Alb)] and body composition were analyzed. Results Except the 2 patients, the bone morphology, blood indexes and body compositions in other 7 family members were under normal conditions. The phalanx intervals of both hands in 2 patients with mucolipidosis type Ⅲwere widened significantly, among them the thumb manifestation was more obvious; the distal segments of phalanxes in both hands became pointed and curved presenting a "claw-like hand" deformity; the metacarpal and distal carpal metaphysis were obviously enlarged, and scaphoid, lunate, trianglar, orbicular, and trapezium and trapezoid bones were loosely arranged at the wrist; the distal ends of ulna and radius were markedly enlarged. Compared to healthy people, the triglyceride levels of serum in the 2 patients were obviously reduced (the percentage of reduction: 57.14% and 41.07% respectively); body mass indexes (BMI), total fat and visceral fat were significantly lowered (BMI reduction percentage:26.81% and 14.55%, total fat reduction percentage: 38.12% and 44.95%, visceral fat reduction percentage: 62.25% and 67.74%, respectively) in the two patients. Conclusion The purpose of studying the biochemistry indexes, imaging characteristics and body compositions is to more deeply understand the clinical symptoms and signs of the 2 sibling patients with mucolipidosis type Ⅲ in a family to provide a theoretical reference.
5. Treatment options of early-stage lung cancer: surgery or stereotactic body radiotherapy
Yanling WU ; Qingfu FENG ; Xiaodan WANG ; Qiang ZENG
Chinese Journal of Radiation Oncology 2019;28(9):709-712
For the treatment of early non-small cell lung cancer, surgery is still one of the most important curative treatments. Lung segment or subsegment resection under video-assisted thoracoscopic surgery is becoming more and more popular. With the development of radiotherapy technology, Stereotactic Body Radiotherapy (SBRT) has achieved the similar or the same curative effect as surgery. It has become an indisputable curative treatment for patients who can not or refuse surgery, and there are still some disputes among those who can operate. Therefore, this review will elaborate on these treatment methods in order to help update the concept and provide more treatment methods and obtain more benefits for patients. Although it is no randomized clinical trial to compare SBRT with surgery, we suggest that SBRT is the curative treatment for patients who can not or refuse surgery. Especially for the elderly, or patients with cardiopulmonary diseases, diabetes and other high-risks. SBRT should become the main treatment methods, because its curative effect is not inferior to surgery and its complications are fewer and lighter. Therefore, for the treatment of non-small cell lung cancer in the early stage, it is more importent to choose individualized treatment methods so as to more benefit.