Objective To investigate the effects of CT-guided cervical approach neurolytic therapy of glossopharyngeal nerve in the treatment of glossopharyngeal neuralgia and intractable pain of glossopharyngeal nerve innervation area. Methods A total of 16 cases of glossopharyngeal neuralgia (Group A) and 12 cases of intractable pain of glossopharyngeal nerve innervation area (Group B) were included in this study. Under the guidance of CT scanning, a percutaneous needle puncture was carried out located on the anterior border of the styloid process at the level of the second cervical vertebra. The 7% phenol glycerin solution was injected after the glossopharyngeal nerve was blocked by the local anesthetic. Results The complete remission rate and the total effective rate in the Group A were 87.5% (14/16) and 100% (16/16), respectively. The corresponding values in the Group B were 50% (6/12) and 83.3% (10/12), respectively. Follow-up observations for 6 months found no recurrence in the Group A and 6 cases (50.0%) of recurrence in the Group B. No severe complications occurred in both of groups. Conclusions CT-guided cervical approach neurolytic therapy of glossopharyngeal nerve is characterized by high reliability, accurate location, good operational safety, and fewer complications.

Cancer is one of the main diseases that threaten the health of human.In order to increase the cure rate of cancer,the accurate therapy of cancer must be developed speedily.The most effective method for curing cancer is intensity modulated radiation therapy(IMRT),which can increase the local control rate of cancer and decrease complications of tissues.IMRT is considered to be an important breakthrough in cancer therapy.The dose produced by it is better than 3D-CRT and can achieves better results of therapy,which has been confirmed in the clinical therapies of head cancer,neck cancer,prostate cancer,breast cancer,cervical cancer and pancreas cancer etc.The developing course of IMRT,the methods of intensity modulation,the enforcement process of IMRT and the feasibility test of therapy plans are emphatically introduced.