1.Occupational Health Investigation in Workers Engaged in House Decoration
Wentao SI ; Qingbi ZHANG ; Yulin LI
Journal of Environment and Health 2007;0(12):-
Objective To study the health effect of harmful substances produced in house decoration through the investigation of occupational heath impacts in the workers engaged in house decoration.Methods From July to October in 2007, in Luzhou,200 workers engaged in house decoration and 200 building workers were selected.The questionnaires investigation was conducted on general condition,working circumstances,living conditions,personal protect and health status.Results All the workers had little knowledge about the health impacts caused by house decoration materials.The working circumstance of the workers engaged in house decoration was bad and almost no personal protection in working.In house decoration workers,the prevalence rate of dermal redness(13%),dryness(10%),headache(8.0%),vertigo(9.5%),cough(15.5%),asthma(8.5%),chest tightness(7.5%) nausea(8%),vomit(5%),discomfort sense in eyes(30.0%),eyes ache(15.0%),photophobia lacrimation(15.0%), abnormal smell(15.0%),nasopharyngeal discomfort(12.5%) and sore throat(10.5%) was higher compared with the building workers (P
2.Mechanisms of Traditional Chinese Medicine in Prevention and Treatment of Stroke by Regulating Ferroptosis: A Review
Mingyan WEI ; Shanze LI ; Rui HAN ; Qingbi LI ; Xingyi SUN ; Han ZHANG ; Lin LI
Chinese Journal of Experimental Traditional Medical Formulae 2025;31(12):313-321
Stroke is one of the leading causes of death and disability worldwide, ranking as the second leading cause of mortality globally and the primary cause of adult disability. Its pathological process involves complex cascade mechanisms, with high incidence and disability rates, posing a major threat to human health. According to statistics from the World Health Organization, more than 13 million new cases of stroke occur globally each year, resulting in direct medical costs and socioeconomic burdens amounting to hundreds of billions of dollars. In recent years, breakthroughs in the study of programmed cell death mechanisms have provided new insights into stroke treatment. Among them, ferroptosis, a novel form of cell death driven by iron-dependent lipid peroxidation, has attracted widespread attention in the pathological process of stroke. Ferroptosis is closely associated with iron metabolism disorders, oxidative stress, and lipid peroxidation, and exhibits unique regulatory effects in key pathological processes of stroke, such as ischemia-reperfusion injury, disruption of the blood-brain barrier, and neuronal apoptosis. It plays an important role in post-stroke neurological damage. Chinese medicine, as an essential component of traditional Chinese medicine (TCM), has demonstrated advantages in modulating ferroptosis and exerting neuroprotective effects. This review systematically summarizes current research on the neuroprotective mechanisms of Chinese medicine compound formulas and monomers through the regulation of ferroptosis pathways in post-stroke conditions, aiming to provide a basis for optimizing clinical treatment strategies and exploring new therapeutic approaches, and to offer new strategies and approaches for stroke treatment.
3.Mechanisms of Traditional Chinese Medicine in Prevention and Treatment of Stroke by Regulating Ferroptosis: A Review
Mingyan WEI ; Shanze LI ; Rui HAN ; Qingbi LI ; Xingyi SUN ; Han ZHANG ; Lin LI
Chinese Journal of Experimental Traditional Medical Formulae 2025;31(12):313-321
Stroke is one of the leading causes of death and disability worldwide, ranking as the second leading cause of mortality globally and the primary cause of adult disability. Its pathological process involves complex cascade mechanisms, with high incidence and disability rates, posing a major threat to human health. According to statistics from the World Health Organization, more than 13 million new cases of stroke occur globally each year, resulting in direct medical costs and socioeconomic burdens amounting to hundreds of billions of dollars. In recent years, breakthroughs in the study of programmed cell death mechanisms have provided new insights into stroke treatment. Among them, ferroptosis, a novel form of cell death driven by iron-dependent lipid peroxidation, has attracted widespread attention in the pathological process of stroke. Ferroptosis is closely associated with iron metabolism disorders, oxidative stress, and lipid peroxidation, and exhibits unique regulatory effects in key pathological processes of stroke, such as ischemia-reperfusion injury, disruption of the blood-brain barrier, and neuronal apoptosis. It plays an important role in post-stroke neurological damage. Chinese medicine, as an essential component of traditional Chinese medicine (TCM), has demonstrated advantages in modulating ferroptosis and exerting neuroprotective effects. This review systematically summarizes current research on the neuroprotective mechanisms of Chinese medicine compound formulas and monomers through the regulation of ferroptosis pathways in post-stroke conditions, aiming to provide a basis for optimizing clinical treatment strategies and exploring new therapeutic approaches, and to offer new strategies and approaches for stroke treatment.