Medical ethics has its own characteristics on curriculum setup,teaching goals,the structure of teaching staff in America,France and China,It is beneficial for our feform in education in medical ethics to learn and refer to the experiencs of the success abroad.

Animals ; Cerebral Cortex ; cytology ; physiology ; Delayed Rectifier Potassium Channels ; physiology ; Neurons ; physiology ; Patch-Clamp Techniques ; Rats ; Rats, Sprague-Dawley

The rational design of teaching contents of physical pharmacy plays an important role in the class teaching.Some practices of designing teaching contents are expounded in detail,including the combination with teaching cases,the integration of the teaching contents,the combination with the research results of the physical pharmacy,and the combination with the pharmaceutical experiments of traditional Chinese medicine.The innovation of this research is the combination of theory and practice and the infiltration between teaching and scientific research.It also puts forward some measures such as continually accumulating and improving the related material,and constructing a rich,shared source material storehouse,etc..

Objective : To investigate the prevalence of electronic cigarette use among adult residents at ages of 15 years and older in Tongzhou District, Beijing Municipality, so as to provide insights into formulation of tobacco control interventions. Methods: Permanent residents at ages of 15 years and older were sampled using a stratified multi-stage cluster random sampling method in Tongzhou District from September to October, 2021, and subjects' demographics, electronic cigarette use, and exposure to electronic cigarette advertising were investigated using the 2021 Questionnaire for Adult Tobacco Survey in Beijing. The awareness of electronic cigarette knowledge, prevalence of electronic cigarette use, route of acquiring electronic cigarette knowledge and route of exposure to electronic cigarette advertising were analyzed among residents in Tongzhou District, and factors affecting electronic cigarette uses were identified using a multivariable logistic regression model. Results: A total of 1 196 questionnaires were allocated, and 1 166 valid questionnaires were recovered, with an effective recovery rate of 97.49%. The respondents included 532 men (45.63%) and 634 women (54.37%), with a mean age of (57.05±15.04) years. The awareness of electronic cigarette knowledge was 67.58%, and the prevalence of electronic cigarette uses and current electronic cigarette uses was 3.94% and 0.34%, respectively. Multivariable logistic regression analysis showed a higher possibility of electronic cigarette uses among men (OR=28.492, 95%CI: 6.873-118.106), residents at ages of 15 to 44 years (OR=3.219, 95%CI: 1.584-6.539), enterprise workers/businessmen/service industry workers (OR=3.599, 95%CI: 1.527-8.482), and public institution workers/public servants/students (OR=4.403, 95%CI: 1.758-11.026). The main route of acquiring electronic cigarettes was presented by others (43.48%), and the main cause of electronic cigarette use was quitting smoking (30.43%), followed by thinking little harmlessness of electronic cigarette use (26.09%), while the main route of exposure to electronic cigarette advertising was television (59.09%), followed by internet (45.45%). Conclusions There is a low prevalence rate of electronic cigarette uses among residents at ages of 15 years and older in Tongzhou District, and men and residents at ages of 15 to 44 years are main electronic cigarette users. Health education pertaining to the harmlessness of electronic cigarette uses and supervision of electronic cigarette advertising are required to be reinforced.

Objective: To investigate the influencing factors for hemodynamics in lower limbs and provide information for prevention of deep venous thrombosis (DVT) in lower limbs after stroke. Methods: According to the degree of paralysis in limbs, the stroke patients were divided into muscle strength ≤3 grade group (n = 53) and > 3 grade group (n = 94), and the maximum venous outflow (MVO) in lower limbs was detected by pulse volume recorder. The relationship was analysed between MVO and age, blood pressure, muscle strength, cholesterol, glycerinate, plasma fibrinogen and level of plasma von Willerbrand factor (vWF). Results: The reduction of MVO is correlated with the degree of paralysis of lower limbs. There were negative correlation between MVO and the level of plasma vWF (r = -0.2571, P = 0.02). Conclusion: The level of plasma vWF and muscle strength has some effects on MVO in lower limbs during the acute stage after stroke.

ObjectiveTo explore the clinical features of senile coronary heart disease.MethodsClinical data of 367 cases with senile coronary heart disease admitted from January 2001 to December 2004 were reviewed.ResultsOf the 367 cases with senile coronary heart disease, 42 were asymptomatic, 92 were angina pectoris, 56 were myocardial infarction, 66 were arrhythmia, 74 were angina pectoris or myocardial infarction with arrhythmia, 37 were angina pectoris or myocardial infarction with cardiac insufficiency. Of the 79 cases with myocardial infarction, 47 were myocardial infarction with Q wave, 32 were myocardial infarction without Q wave. Of the 140 cases with arrhythmia, many cases were varied arrhythmias, 51 were atrial flutter or atrial fibrillation, 37 were ventricular premature beat, 34 were atrial premature beat, 27 were intraventricular block, 12 were atrioventricular block, 8 were sick sinus syndrome.ConclusionThe clinical features of senile coronary heart disease manifested asymptomatic, atypical angina pectoris, arrhythmias, cardiac insufficiency, varied coronary heart disease, myocardial infarction are myocardial infarction without Q wave, etc.

Objective:To make clear which drugs can cause drug eruption.Methods:Clinical analysis was made based on the patients data regarding the types of the drup eruption and the severity of liver impairment.Results:There are four types of drugs which can cause drug eruption:antibiotics (55.3%),antipyretic analgesic(26.6%)，Chinese medicine (9.6%) and biological preparations (8.5%).The drug eruptions usually manifested as unticaria,measles-like eruption,multiform erythma and stable eruption.Conclusion:The main allergic drugs are antibiotics and antipyretic analgesic.However,attention should also be payed to the Chinese medicine and biological preparations.

Thyroid carcinoma is one of the most common diseases in the head and neck area. With the advance of innovative technologies like ultrasound ,fine-needle aspiration and PET-CT, the number of patients diagnosed as thyroid carcinoma has grow rapidly during the past ten years. As a special structure in papillary tumors and appearing as microcalcification in the imaging examination, psammoma body has been considered of great significance in the diagnosis of thyroid carcinoma. Psammoma body has unique features in terms of pathology, cytology and imageology.The study of the mechanism of psammoma body formation is very important for the clinic to differentiate the disease from others. In this article, we summarized the role of psammoma body in the study of thyroid cancer.

Objective To investigate the efficacy of pulse index continuous cardiac output (PICCO) monitoring in maintaining adequate blood volume in patients undergoing off-pump coronary artery bypass grafting (OP-CABG).Methods Forty-seven ASA Ⅰ-Ⅲ patients aged 43-64 yr weighing 50-85 kg undergoing OP-CABG were included in this study. Global end-diastolic volume (GEDV), extravascular lung water (EVLW), global end-diastolic volume index (GEDVI), MAP, cardiac output (CO) and cardiac index (CI) were monitored by using PICCO monitor before induction of anesthesia (baseline), at the end of operation and at 4 and 8 h after operation. Blood volume was maintained during operation by adjusting the volume and infusion rate of succinyl gelatin and lactated Ringer's solution according to volume indexes and hemodynamic indexes. GEDVI was maintained at 600-800 ml/m2 and Hct≥30% by transfusion of whole blood or erythrocyte suspension;MAP was maintained at 70-90 mm Hg by intravenous infusion of nitroglycerine (0.5-1.0 μg·kg-1·min-1) or diltiazem (2-6 μg·kg-1·min-1); HR was maintained at≤75 bpm by intravenous dopamine infusion (3-5 μg·kg-1·min-1). The oxygen delivery index(DO2 I) and oxygen consumption index (VO2 I) were calculated. Arterial blood samples were taken for blood gas analysis. Results The CI, DO2I and VO2I were increased at the end of operation, and at 4 h and 8 h after operation as compared with the baseline values before induction of anesthesia (P<0.05 or 0.01). Conclusion Perioperative blood volume can be well maintained with PICCO monitoring in patients undergoing off-pump coronary artery bypass grafting.

Heart Defects, Congenital ; complications ; surgery ; Humans ; Hypertension, Pulmonary ; etiology ; surgery