1.Comparative study on English translations of traditional Chinese medicine terms for liver and gallbladder diseases
Jian DONG ; Qing WU ; Ning CHEN
International Journal of Traditional Chinese Medicine 2014;(11):1021-1024
Objective This paper addresses the standardization of traditional Chinese medicine(TCM) nomenclature translation and put forward suggestions through a comparative study on English translations of TCM terms for liver and gallbladder diseases.Method With the principle of standardization, the principle of correspondence, the principle of readability and the principle of nationalism as the possible criteria, translations of 8 TCM terms available in 7 publications at home and abroad are compared and analyzed.Results 5 of the 8 terms have at least two English versions. The principle of standardization and the principle of readability are violated more frequently than the other two.Conclusion The standardization of TCM nomenclature is progressing steadily.However, efforts are still necessary for translators to improve English language proficiency. The principle of standardization and the principle of readability need to be further enhanced.
2.Multiple factors analysis on the healthy lifestyle of college students
Dong WANG ; Xianbo WU ; Qing CHEN
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(5):444-446
Objective To explore the influential factors of the healthy lifestyle of college students, so as to provide basis for drafting the health education measure appropriate for college students. Methods 5400 college students received the assessment with the healthy lifestyle scale for college students to analyze the influential factors. Results Some factors affect the healthy lifestyles of college students, such as gender, temperament, self-rated health, self-rated achievement, type of college, grade, residential peer, birth region, educational levels of parents and family' s monthly-earning, and r -square for total score and each dimension of the healthy lifestyle of college students respectively were 0. 3202,0. 4173,0. 2104,0. 2247,0. 1936,0. 0922,0. 2013,0. 2181,0. 162. Conclusion Colleges should take different measures to stimulate student interest in taking health-promoting lifestyles based on their characteristics so as to develop healthy lifestyles during their college student life.
3.English translation purposes and principles for traditional Chinese medicine terms
Jian DONG ; Ning CHEN ; Qing WU
International Journal of Traditional Chinese Medicine 2014;(9):773-775
Standardization of traditional Chinese medicine(TCM)term translation is the focus of TCM translation studies. Based on the Skopos theory and our interviews to 6 internationals, this paper aims to explore the purposes and principles of TCM term translation from the perspective of the client, the translator and the addressee. Finally, four fundamental principles of TCM term translation are summarized in order to provide references for the standardization of TCM term translation.
4.Low dose thalidomide combined with VAD regimen contained one-week dexamethasone on 42 cases of patients with multiple myeloma
Yanjun WANG ; Jie WU ; Qing DONG ; Ting WANG ; Xueyong ZHANG
Cancer Research and Clinic 2011;23(7):479-482
Objective To observe the efficacy and toxicity of low dose thalidomide combined with VAD regimen contained one-week dexamethasone in treatment on patients with multiple myeloma (MM). Methods 42 patients with MM were diagnosed in our hospital.The VAD regimen contained one-week dexamethasone was vincristine 0.4 mg/d, adramycin 10 mg/d and dexamethasone 40 mg/d for 4 days. At the same time, thalidomide is given 150-200 mg/d. Results The overall response rate (ORR) is 80.95%. Before and after treatment, all the detection indicators in MM patients were statistically different (P<0.001). There is small adverse reactions. Conclusion Low dose thalidomide combined with VAD regimen contained one-week dexamethasone in treatment of MM has more merits such as less side effects, good tolerance, convenient administration and significant curative effects, so it should be recommended in clinical works.
5.The relationship between expression of cyclooxygenase-2,vascularendotheliai growth factor and angiogenesis in hepatoceUular carcinoma
Dong-Mei ZOU ; Qing-Xu YANG ; Tong-Tong WU ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To investigate the significance of cyclooxygenase-2 (COX-2),vascular endothelial growth factor(VEGF) protein expression and angiogenesis in hepatocellular carcinoma(HCC).Methods Tissue sec- tions from 40 HCC patients were examined immunohistochemically for protein expression of COX-2 and VEGF.Mi- crovessel density(MVD) was counted by endothelial cells immunostained by anti-CD34 antibody.Results The ex- pression of COX-2 protein in well differentiated HCC was stronger than that in moderately differentiated HCC and poorly differentiated HCC(P
6.Inhibition effect of Heme oxygenase-1 activator Copp on irradiation-induced endothelial cell apoptosis
jing, YU ; guo-hua, WU ; qing, LIN ; ren-hua, ZHOU ; dong-qing, LU ; jia, WANG ; qian, LIU ; xiu-yan, FEN
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(12):-
Objective To explore protective effect of Heme oxygenase-1(HO-1) on irradiation-induced endothelial cell apoptosis.Methods Human endothelial cell line EA.hy926 were administered with or without HO-1 activator Copp and/or HO-1 inhibitor Znpp,respectively.Then,cells were treated with or without 8 Gy radiation.The HO-1 protein expression of cells were assessed with Western blotting and apoptosis of cells treated with irradiation were evaluated with flow cytometry.Moreover,cytochrome C releasing into cytosol were also determined by Western blotting. Results In PBS+R group,HO-1 protein expression of EA.hy926 was low posterior to irradiation.When cells were preconditioned with Copp and/or Znpp,then recieved with 8Gy irradiation,the HO-1 protein expression of EA.hy926 increased significantly in comparision with the PBS+R group(P
7.Simulation study on acoustic source reconstruction of magneto-acoustic tomography with magnetic induction (MAT-MI) based on transducer.
Shigang WANG ; Dong CUI ; Yingying WU ; Minjuan YOU ; Weifang CAO ; Yongxin GUO ; Qing JIAO
Chinese Journal of Medical Instrumentation 2015;39(1):13-24
OBJECTIVEIn order to accurately reconstruct the acoustic source image, the application of transducer's receiving characteristics in magneto-acoustic tomography with magnetic induction (MAT-MI) is studied.
METHODSThe conductivity phantom model is built, and the magnetic acoustic signals are simulated and the acoustic sources are reconstructed according to the transducer's receiving characteristics.
RESULTSThe reconstructed image of acoustic source is consistent with the topographic shape and size of the phantom model.
CONCLUSIONMAT-MI based on the transducer's characteristics lays the foundation for further study.
Acoustics ; Magnetic Phenomena ; Magnetics ; Tomography ; Transducers
8.Treatment of HBeAg positive chronic hepatitis B by xiaoyao powder combined with interferon-alpha: a clinical observation.
Hui-qing LIANG ; Jin-mo TANG ; Chun-cheng WU ; Shao-dong CHEN
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(6):666-670
OBJECTIVETo study the efficacy of Xiaoyao Powder (XYP) combined with interferon alpha (IFN-alpha) in treating HBeAg positive chronic hepatitis B (CHB) patients and the effect on their quality of life (QOL).
METHODSTotally 193 patients with HBeAg-positive CHB confirmed by liver biopsy were randomly assigned to 2 groups, Group A (94 cases) and Group B (99 cases). IFN-alpha1b was subcutaneously injected to patients in Group A at the dose of 50 microg, thrice per week. Those in Group B additionally took XYP. The therapeutic course for all was 24 weeks. Clinical efficacy was observed by assessing ALT restoration rate, HBeAg negative rate, HBeAg conversion rate, HBV DNA negative rate, complete response rate, partial response rate, and symptoms integral. The evaluation of QOL was performed by using chronic liver disease questionnaire (CLDQ) score. Adverse reaction occurrence rate was observed in the two groups.
RESULTSBetter effects were obtained in Group A on ALT restoration rate, HBeAg negative rate, HBV DNA negative rate, complete response rate, partial response rate, TCM symptoms integral, the total effective rate of TCM sysmptoms, CLDQ score, and adverse reaction rates, showing statistical difference when compared with Group B (P < 0.05, P < 0.01).
CONCLUSIONXYP could elevate the efficacy of TCM symptoms of HBeAg-positive CHB patients and anti-viral effect, improve their QOL, and reduce adverse reaction of IFN-alpha.
Adult ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Hepatitis B e Antigens ; Hepatitis B, Chronic ; drug therapy ; Humans ; Interferon-alpha ; therapeutic use ; Male ; Quality of Life ; Treatment Outcome
9.Intravenous drug abuse-related infective endocarditis: report of an autopsy case.
Wei-xiang ZHONG ; Dong-ping TIAN ; De-qing WU ; Min SU
Chinese Journal of Pathology 2010;39(6):421-422
Adult
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Aortic Valve
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microbiology
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pathology
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Autopsy
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Brain
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microbiology
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pathology
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Endocarditis, Bacterial
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complications
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microbiology
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pathology
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Female
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Heart Ventricles
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microbiology
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pathology
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Humans
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Mitral Valve
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pathology
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Sepsis
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complications
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microbiology
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pathology
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Substance Abuse, Intravenous
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complications
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microbiology
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pathology
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Young Adult
10.Effect of Methylene Blue on Blood-brain Barrier after Focal Cerebral Ischemia-reperfusion in Rats
Min WU ; Qing FANG ; Zhongfang SHI ; Lixin XU ; Liping DONG ; Xu YAN ; Shaohua YANG ; Fang YUAN
Chinese Journal of Rehabilitation Theory and Practice 2016;22(2):125-131
Objective To investigate the protective effect of methylene blue (MB) on blood-brain barrier (BBB) injury after focal cere-bral ischemia-reperfusion in rats. Methods 18 male Sprague-Dawley rats were randomly divided into sham-operated group (n=6), model group (n=6) and MB treatment group (n=6). The left middle cerebral arteries were occluded for 1 hour and reperfused. MB was infused intra-venously immediately after reperfusion (3 mg/kg) and again 2 hours post-reperfusion (1.5 mg/kg), while normal saline was administered in the model group. The sham-operated group was treated as same as the model group without occlusion and infusion. HE staining was used to observe the histological injury in the cortex around the infarcted region 47 hours after reperfusion, while albumin immunohistochemistry was used to evaluate the permeability of the BBB, and immunohistochemistry and double immunofluorescence staining were used to exam-ine the expressions of glial fibrillary acidic protein (GFAP) and aquaporin-4 (AQP-4). Results HE staining showed that cells and blood ves-sels were not intact in the cortex around the infarcted region in the model group and they were better in the MB treatment group. The expres-sions of the albumin, GFAP and AQP-4 were higher in the model group than in the sham-operated group (P<0.01), and were lower in MB treatment group than in the model group (P<0.05). The double immunofluorescence staining showed the colocalization of GFAP and AQP-4 in the astrocytes. Conclusion MB may ameliorate the BBB disruption induced by focal cerebral ischemia-reperfusion through reducing glio-cyte proliferation and down-regulation of AQP-4 expression in rats.