1.Research progress in the association of peri-implant diseases and metabolic syndrome.
Qing Ci KONG ; Xiao Jun HU ; Qi Mei GONG
Chinese Journal of Stomatology 2023;58(1):75-80
Peri-implant disease, an important group of diseases that cause implant failure, are associated with metabolic abnormality. Metabolic syndrome (MetS) is a common metabolic disorder comprising abdominal obesity, hyperglycemia, systemic hypertension and atherogenic dyslipidemia. Previous studies had reported that MetS and its diversified clinical manifestations might be associated with peri-implant diseases, but the relationship and underlying mechanisms were unclear. This review aims to explore the relationship between MetS and peri-implant disease, in order to provide beneficial reference for the prevention and treatment of peri-implant disease in patients with MetS.
Humans
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Metabolic Syndrome/complications*
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Peri-Implantitis
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Dental Implants/adverse effects*
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Hypertension/complications*
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Risk Factors
2.A new isoflavone derivative from Rosa Damascena and its antibacterial activity.
Jing LI ; Wei-Song KONG ; Xin LIU ; Yong-Qin GENG ; Jin WANG ; Yong XU ; Xue-Mei LI ; Guang-Yu YANG ; Min ZHOU ; Qiu-Fen HU ; Tao LI ; Ci-Qing JIANG
China Journal of Chinese Materia Medica 2018;43(2):332-335
A new isoflavone derivative was isolated from Rosa damascena by using various chromatographic techniques including silica gel, Sephadex LH-20, and preparative RP-HPLC separation. Its structure was identified as 4'-hydroxy-7-(3-hydroxypropanoyl)-6-methoxy-isoflavone using combined examinations of their UV, IR, MS, and NMR spectroscopic data. Biological activity test showed that this compound showed prominent antibacterial activity with MIC₉₀ value of (46±4) mg·L⁻¹ for methicillin resistant Staphylococcus aureus(MRSA) strain. This value is close to that of levofloxacin [with MIC₉₀ value (53±5) mg·L⁻¹].
Anti-Bacterial Agents
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isolation & purification
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pharmacology
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Isoflavones
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isolation & purification
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pharmacology
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Methicillin-Resistant Staphylococcus aureus
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drug effects
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Microbial Sensitivity Tests
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Phytochemicals
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isolation & purification
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pharmacology
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Rosa
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chemistry