Invasive micropapillary carcinoma of breast is associated with poor prognosis and high incidence of lymph node metastasis.Tumor cells are observed as micro-papillary with light microscope.And high expression of epithelial membrane antigen(EMA) examined by immunohistochemistry is a reliable way of diagnosing this carcinoma accurately and timely.Compared with the previous diagnostic criteria,the new criteria pays more attention to the diagnosis of invasive micropapillary carcinoma of the breast.For this reason,it has important significance for treatment and prognosis of patients with invasive micropapillary carcinoma of the breast.

Objective To investigate the clinical effect of left tactic norgestrel releasing intrauterine system in the treatment of adenomyosis. Methods One hundred and thirty-four patients with diagnosis of uterine adenomyosis were selected as our subjects in Xuanwu Hospital of Capital Medical University from Mar. 2010 to Mar. 2013. They were randomly divided into control group(67 cases)and observation group(67 cases). Patients in control group were give Gestrinone with oral,and in observation group were give left acetylene connaught progesterone intrauterine placed treatment slow-release system. The information of pain scores,menstruation, uterine volume,endometrial thickness were recorded. Results After treatment,pain score,menstrual quantity, uterine volume and endometrial thickness in observation group were(1. 85 ± 0. 57),(45. 37 ± 11. 94)ml, (129. 47 ± 8. 67)mm3 ,(4. 02 ± 2. 04)mm,significantly lower than the control group((4. 82 ± 2. 07),(61. 47 ± 12. 07)ml,(148. 54 ± 12. 47)mm3 ,(6. 35 ± 2. 64)mm),and the differences between groups were statistically significant(t = 5. 397,6. 047,5. 334,4. 681 respectively;P < 0. 05). Conclusion The therapy of levonorgestrel releasing intrauterine system on treating adenomyosis of uterus is safe and effective. It is worthy of promotion.

Objective To investigate the risk factors and clinical features of severe preeclampsia(SP) complicated with multiple organ dysfunction syndrome (Multiple Organ Dysfunction Syndrome,MODS) in order to provide reference for clinical practice.Methods Three hundred and ninety-one cases with severe preeclampsia were selected as our subjects,who hospitalized from February 2005 to February 2014 in our hospital.All subjects were divided into observation group (48 cases with MODS) and control group (343 cases without MODS).Clinical data were collected including age,gravidity,parity,gestational age,gestational age termination of pregnancy,uterine scar,prenatal care,medical history,treatment,mother child outcomes.Results There were significant differences between two groups in terms of weeks of termination of pregnancy,rate of uterine scar,rate of regular check-up of pregnancy,rate of chronic hypertension and renal disease.Logistic results showed that there were relationships between SP complicated with MO)S and the occurrence of termination of pregnancy with gestational age ＜28 weeks (OR =2.046,95％ CI:1.03 ～ 3.74,P =0.034),uterine scar (OR =2.401,95％ CI:1.16 ～ 4.09,P =0.008),non-regular prenatal care (OR =3.167,95％ CI:1.96 ～ 5.23,P =0.002),chronic hypertension (OR =3.348,95％ CI:2.23 ～ 5.78,P =0.001),renal disease (OR =3.064,95％ CI:1.77 ～ 5.18,P =0.038).The rate of underwent special treatment,preterm children,neonatal asphyxia,perinatal death,intracranial hemorrhage in observation group were 77.08％,79.17％,29.17％,20.83％,4.17％,higher than that in control group (23.62％,45.19％,13.70％,8.45％,1.17％ respectively; x2 =10.471,12.147,4.519,8.644,6.648,all P ＜ 0.05).The degree of organ injury score in gestational age ≥ 33 weeks and ＜ 33 weeks were (1.34 ± 0.28) points and (3.64 ± 0.69) points,and the difference was significant.The gestational week in gestational age ≥ 33 weeks and ＜33 weeks were (35.48 ±2.06) weeks and (29.87 ± 1.37) weeks,and the differencewas significant(t =3.917,P ＜0.05).The survival rates were 100％,77.78％,33.33％ when the numbers of damaged organs were 2,3 and ≥ 4.There was significant different between 2 and 3 damaged organs in terms of survival rate (x2 =3.964,P =0.024).Conclusion The risk factors of severe preeclampsia complicated with MODS include termination of pregnancy gestational age ＜ 28 weeks,uterine scar,non-regular prenatal care,chronic hypertension,renal disease.Prognosis of severe preeclampsia patients with MODs was poor than that without MODS and it relates with gestational age,the number of closely related organ damage.

Congenital heart disease(CHD) is one of the main causes of newborn death,which makes the prenatal diagnosis of CHD the hot spot of perinatology.Fetal echocardiography has high sensitivity in diagnosing fetal CHD in mid-gestational age of pregnancy,and is considered world-widely as the gold standard.Rapid advance has been achieved for the past decades in the technology of fetal cardiac magnetic resonance imaging (MRI).The advantages of fetal cardiac MRI including broad vision of interest and good reproducibility could make up for the deficiency of fetal echocardiography.However,some technical problems significantly limit the clinical application of it.Nowadays,fetal cardiac MRI has been utilized as a supplementary method in prenatal diagnosis of fetal CHD.This article reviews the application,advantages and limitations of fetal cardiac MRI in fetal CHD diagnosis.

Professor XU Run-san has been dealt with Chinese medical practice for over 60 years,and was good at theory of pulse and syndrome differentiatiion. During the medical profession career,he concentrated to treating kinds of internal clinical diseases using old ancient formula and had outstanding effects. He claimed to combination Chinese medicine with western medicine in treating female illness. He cured some complicated female diseases successfully,such as dysfunctional uterine bleeding,pelvic inflammatory disease,and endometriosis. In clinic work,he insisted on combination differential diagnosis of diseases with differential syndrome of diseases,formula corresponding with syndrome of diseases.

ObjectiveTo observe the effect of Yitongping decoction on dysmenorrhea in patients with adenomyosis.Methods35 dysmenorrhea cases with adenomyosis were treated with Yitongping decoction orally. Dysmenorrhea scores, uterus size showed by B ultrasound and blood serum CA125 before and after treatment were compared.ResultsAfter treatment of Yitongping decoction, Average dysmenorrhea scores of all patients decreased for 164.5 (P<0.001), the total effective rate was 68.7 %; but quantity of catamenia, uterus size and blood serum CA125 had not changed significantly (P>0.05).ConclusionYitongping is effective for dysmenorrhea patients with adenomyosis that not receiving hysterectomy and hormone treatment.

Objective To study the effect of different analgesia methods on postoperative cellular immune function in patients with radical resection of lung cancer.Methods Fifty patients undergoing selective radical resection of lung cancer were randomly divided into two groups.Group A (25 patients) was given morphine patient-controlled epidural analgesia(PCEA) and group B (25 patients) was given preemptive analgesia with parecoxib combined with morphine PCEA.T-lymphocyte subsets (CD4+,CD8+)and natural killer cell (NK cell) were measured by flow cytometry at preanesthesia,2 h intraoperative,24,48 h postoperative.Results The level of CD4+,CD8+ and NK cell in two groups at preanesthesia had no significant difference (P ＞0.05).The level of CD4+ and CD4+/CD8+ in two groups at 2 h intraoperative,24,48 h postoperative were significantly lower compared with preanesthesia (group A:CD4+:0.252 ± 0.035,0.227 ±0.025,0.248 ± 0.028 vs.0.310 ± 0.032,CD4+/CD8+:1.2 ± 0.1,1.0 ± 0.1,1.1 ± 0.2 vs.1.5 ± 0.2;group B:CD4+:0.265 ± 0.033,0.263 ± 0.028,0.264 ± 0.031 vs.0.312 ± 0.035,CD4+/CD8+:1.3 ± 0.2,1.2 ± 0.1,1.2 ± 0.1 vs.1.4 ± 0.1)(P ＜ 0.05).Compared with group A,the range of descend of CD4+ and CD4+/CD8+ in group B was significantly less at 24,48 h postoperative (P ＜ 0.05).The level of NK cell in two groups at 24,48 h postoperative was significantly lower than preanesthesia(O.112 + 0.019,0.113 + 0.016 vs.0.126 + 0.019 and 0.117 +0.016,0.120 +0.018 vs.0.127 + 0.021) (P ＜0.05).The level of NK cell in group B at 24,48 h postoperative was significantly higher than that in group A (P ＜ 0.05).Conclusion Parecoxib sodium preemptive analgesia combined with morphine PCEA may reduce immune depress in tumor palients by lowering the range of descend of CD4+ and NK cell.

0.05).Conclusion HRCT is surperior to plain CT in grading,especially in the evaluating early lesions of sacroiliac joint,but for the moderate and serious inflammatory changes of AS, both CT and HRCT are equivalent in the diagnosis of sacroiliitis.

Objective The effect of hepatic partial resection for hepatic trauma.Methods Thirty-Six patients with hepatic trauma were operated on the bases of litertures,we elucidated the indication and method of operation and prevention of operative complications .Resuts Three cases died,a death rate of 8 33%,and a cure rate of 91 8%.Conclusion Hepatic partial resection is an effective method for treatment of hepatic trauma.