Objective:To study the application of students as standardized patients in orthopedical practice teaching of foreign medical students.Methods:A total of 116 students who received Surgical practice teaching in Affiliated Renhe Hospital of China Three Gorges University from January 2014 to December 2017 were randomly divided into two groups. Bedside teaching model was adopted in the control group ( n=58) to help the interns manage the in-patients under the guidance of the teacher. Additional teaching using standardized patients was applied 1 to 2 times per week in the experimental group ( n=58) on the basis of control group. After the teaching, practical test and assessment survey were adopted to evaluate the effectiveness of teaching. SPSS 13.0 was used to analyze the data by t-test. Results:The scores of the practical test of the experimental group were significantly higher than those of control group, such as history taking [(15.23±3.15) vs. (13.56±3.54), P=0.008], physical examination [(17.24±4.23) vs. (10.32±3.75), P=0.000], and basic skill [(17.32±2.58) vs. (13.22±3.65), P=0.000]. The assessment survey showed that learning motivation [(8.25±1.04) vs. (4.82±0.93), P=0.000], and communication ability [(6.22±1.12) vs. (5.59±0.89), P=0.001] of the experimental group were effectively improved than those of the control group. Conclusion:The teaching mode using standardized patients can effectively improve the learning motivation and clinical practical skills of foreign medical students, as well as the teaching quality.