1.Clinical effect of AcrySof Toric intraocular lens implantation for corneal astigmatism correction
Cheng, JIANG ; Zhi-Yi, WEI ; Qin, YANG
International Eye Science 2014;(8):1481-1483
AIM: To evaluate the clinical effect and the rotational stability of AcrySof Toric intraocular lens ( IOL ) implantation to correct preexisting corneal astigmatism in cataract surgery.
METHODS: Twenty-three patients ( 28 eyes ) were enrolled from the department of ophthalmology in the first Affiliated Hospital of Nanjing Medical University. All patients underwent similar phacoemulsification procedure combined with AcrySof Toric IOL implantation from June 2012 to December 2013. The uncorrected visual acuity ( UCVA ) , best corrected visual acuity ( BCVA ) , anticipated residual astigmatism, postoperative residual astigmatism, and Toric IOL axis were detected and measured.
RESULTS:Three months after operation, the UCVA of all eyes were 0. 75±0. 16 and the BCVA were 0. 84±0. 15, there was no significant difference between UCVA and BCVA ( t = 1. 036, P>0. 05 ). The anticipated residual astigmatism was ( 0. 28±0. 12 ) D. The actual residual astigmatism after 3mo of the operation was (0. 42±0. 17) D. There was no significant difference between anticipated and actual residual astigmatism (t=1. 259, P>0. 05). The mean axis rotation of Toric IOL was 3. 02o±1.56o (0o-7o) after 1d of operation and 3. 28o±1. 85o (0o-7o) after 3mo. Among all the eyes, 25 eyes ( 89%) rotated <5o, in 3 eyes (11%) rotated 5o-7o.
CONCLUSION: The AcrySof Toric IOL implantation shows good effectiveness, predictability and stability in correcting pre-existing astigmatism in cataract patients.
2.Application of proteomic techniques in pediatric research.
Wei-qin ZHOU ; Xiang-yong KONG ; Zhi-chun FENG
Chinese Journal of Pediatrics 2011;49(7):526-530
Child
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Humans
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Proteomics
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methods
3.Effect of kanglaite injection combined with Chinese drug therapy according to syndrome differentiation on quality of life and immune function in patients with advanced lung cancer.
Zhi-Feng QIN ; Pin-Kang WEI ; Jun LI
Chinese Journal of Integrated Traditional and Western Medicine 2002;22(8):618-619
Adenocarcinoma
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drug therapy
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immunology
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Aged
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Aged, 80 and over
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Carcinoma, Squamous Cell
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drug therapy
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immunology
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Drugs, Chinese Herbal
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therapeutic use
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Female
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Humans
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Killer Cells, Natural
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immunology
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Lung Neoplasms
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drug therapy
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immunology
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Male
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Middle Aged
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Phytotherapy
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Quality of Life
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T-Lymphocyte Subsets
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immunology
5.Effect of leptin on plasma cholesterol in mice with hyperlipemia.
Wei-qiang CHEN ; Dian-xin LIU ; Zhi-qin XU
Chinese Journal of Applied Physiology 2003;19(2):206-207
Animals
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Cholesterol
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blood
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Hyperlipidemias
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blood
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drug therapy
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Leptin
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pharmacology
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therapeutic use
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Male
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Mice
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Mice, Inbred Strains
6.Differentiation of neural stem cells transplanted into ventral horn of spinal cord after brachial plexus avulsion
Zhi-Yuan TU ; Wen-Ming ZHANG ; Wei-Qin ZHU ; Zhi-Hong ZHENG ; Jian-Shi HU ;
Chinese Journal of Microsurgery 2000;0(03):-
Objective To study the survival,migration and differentiation of the neural stem cells which transplanted into ventral horn of spinal cord after brachial plexus avulsion.Methods Neural stem ceils isolated from spinal cord of neogenetic rats and cultured,expanded,labeled by BrdU before transplanted. Twenty adult healthy SD rats preformed as the model of brochial plexus avulsion(Roots C_(5~7)),then transplan- rod stem ceils into the C_6 ventral horn of spinal cord.On 1,2,4,8,12 weeks postoperatively,immunohisto- chemistry assay were carried out in the spinal cord.Results Transplanted into ventral horn of spinal cord after brachial plexus avulsion.Neural stem cells can survive,migrate for at least one segment of spinal cord and differentiate to neurons and astrocytes.The differentiation of stem cells were time-depends.Conclusion Neural stem cells can survive,migrate and differentiate after transplanted into ventral horn of spinal cord in the rats which suffered from brachial plexus avulsion.
7.Expression of matrix metrallproteinase-2 in human tears fluid after LASlK
Ai-Wei, CHEN ; Hong-Pei, JI ; Wei-Wei, ZHANG ; Hong, GU ; Zhi-Ling, ZHANG ; Ju-Qin, FU
International Eye Science 2014;(12):2229-2231
AlM: To monitor long - term changes of matrix metalloproteinase-2 ( MMP-2 ) in human tears fluid after laser in situ keratomileusis ( LASlK) .
METHODS: Thirty - two myopia cases ( 64 eyes ) underwent uneventful LASlK were enrolled in the study. Tear fluid were collected and MMP-2 expression was analyzed by Western - bolt assay preoperatively and postoperatively on 15d, at 1, 3mo, and 1a.
RESULTS:LASlK increased the concentration of MMP-2 in human tear fluid. At 15d postoperatively, the magnitude of MMP-2 was 1. 4 times that of preoperative, thereafter subsided, but didn't return to preoperative level by 3mo ( P < 0. 05 ). Up to 1a after surgery, the concentration of MMP-2 almost recovered (P>0. 05).
CONCLUSlON: MMP- 2 is significantly expressed in human tear fluid after LASlK, then subsided with time, but didn't return to preoperative level by 3mo and almost recovered up to 1a, indicating wound healing of LASlK would continue up at least 3mo after surgery and almost recovered 1a postoperatively.
8.Type 1 neurofibromatosis with bone and nodal involvement: report of a case.
Xiao-li LIU ; Xiao-qin ZHANG ; Rong WEI ; Chen WANG ; Zhi LÜ
Chinese Journal of Pathology 2010;39(3):195-196
Adult
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Bone and Bones
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pathology
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Disarticulation
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methods
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Hip Joint
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surgery
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Humans
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Lymph Nodes
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pathology
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Male
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Neoplasm Invasiveness
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Neurofibromatosis 1
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pathology
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surgery
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Skin Neoplasms
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pathology
;
surgery
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Young Adult
9.Detection of Fonsecaea, Sporothrix and Penicillium marneffei in paraffin wax embedded tissues by nested PCR
Wei QIN ; Yabo YANG ; Dongmei QUE ; Sha LU ; Yongxuan HU ; Zhi XIE ; Liyan XI
Chinese Journal of Dermatology 2011;44(8):544-547
Objective To evaluate the performance of nested PCR in the detection of different fungi in paraffin wax embedded tissues. Methods Forty-four tissue samples were resected from rats infected with Fonsecaea monophora, patients with chromoblastomycosis, sporotrichosis or penicilliposis marneffei followed by preparation of paraffin wax embedded tissue sections for pathological examination and DNA extraction. Nested PCR was performed by using specific primers targeting the ribosomal DNA of Fonsecaea, Sporothrix and Penicillium marneffei, respectively. The sensitivity and specificity of nested PCR were analyzed and compared with those of pathological examination. Results The nested PCR showed positive results in 8 of 20 samples from rats with chromoblastomycosis, 7 of 10 samples from patients with sporotrichosis and all of the 10 samples from patients with penicilliposis marneffei, but not in the control samples. In the detection of Fonsecaea,Sporothrix schenki and Penicillium marneffei, the sensitivity was 40% ,70% and 100%, respectively, and the specificity was consistently 100%, for the nested PCR. Pathological examination revealed fungal elements in 95%, 70% and 80% of the corresponding samples, respectively. Conclusion Detection of fungal DNA in paraffin wax embedded tissue by nested PCR can be applied to the diagnosis of deep mycosis, especially to the diagnosis of penicilliposis marneffei.
10.STUDY ON MULTIMEDIA TEACHING METHOLDS OF MICROBIOLOGY
Jia-Li LU ; Jun-Zhe QIN ; Zhi-Wei ZHANG ; Jin-Ping LIU ;
Microbiology 1992;0(06):-
Microbiology is one of the fundamental courses in life science and its theories and application techniques are being developed rapidly, in order to arouse the students interest and help them master better the knowledge of microbiology, we have attemped an exploration and reform in the traditional teaching methods of this subject, our study would center on multimedia teaching methods of microbiology, its content were chiefly multimedia microbiology; multimedia microbiology experiment and microbiology network teaching.