1.Psychoreaction of impoverished undergraduate to social support
Chinese Journal of Tissue Engineering Research 2005;9(40):139-141
BACKGROUND: Impoverished undergraduate is a new and special group appearing under the market economy. Strengthening depth and extent is necessary to probe into and study it.OBJECTIVE: To investigate the social support of impoverished undergraduates and probe into its effect on mental health of impoverished undergraduates.DESIGN: Cross-section survey, clustering stratified sampling SETTING: College of Education of Jiangxi Normal University PARTICIPANTS: Totally 445 impoverished undergraduates of Jiangxi Normal University, Nanchang University, Jiangxi Medical College, East China Jiaotong University and so on of nanchang city were recruited in October 2002. All the participants were volunteers.METHODS: Social Support Rating Scale (SSRS) was used to evaluate the social support of impoverished undergraduates. The scale is composed of 10 items including objective support, subjective support, and utilization degree of support. Symptom Checklist 90 (SCL-90) was used to evaluate the mental health status of impoverished undergraduates. SCL-90 has 90 tests, using 1 to 5 degree to score( from not present to severe), including somatization, obsessive compulsive, interpersonal sensitivity, depression,anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism (9 factors). During the process of investigation, the testee was tested singly in 2 hours without interference and influence of others. The questionnaires were taken back and the authenticity and validity of the questionnaires was verified.RESULTS: All the 500 questionnaires handed out were taken back. Totally 445 pieces of effective questionnaires were involved in the analysis with the effective rate of 89%. ① There was significant difference in objective support and utilization degree of the support between the impoverished undergraduate of either gender (P < 0.01 or P < 0.05); ②There were significant differences in subjective support and utilization degree of support between only-child and non-only-child (P < 0.01 or P < 0.05);③ There was significant difference in utilization degree of the support between impoverished undergraduates from city and impoverished undergraduates from country(P < 0.01 or P < 0.05 );④Obvious correlation existed between mental health and social support of the impoverished undergraduates;⑤Through regression analysis, it showed that social support had significant effect on the mental health of impoverished undergraduate (F= 12.770,P=0.000).CONCLUSION: Significant difference existed between different genders,only-child or non-only-child, impoverished undergraduates coming from urban area or rural area. Social support has significant effect on the mental health of impoverished undergraduates.
2.THE APPLICATION OF IMPROVED STANDARDIZED EXECUTION IN PREVENTION AND CONTROL OF HOSPITAL INFECTION
Modern Hospital 2015;(3):113-114
Objective To study and summarizes the methods ofthe standardized hospital infection manage -ment technology in order to prevent and control hospital infection scientifically .Methods Taking the chance of im-provingthe execution of the standardized hospital infection management issued by the Ministry of Health ,we realized organizational execution by enhancing the responsibility decomposition , mechanism implementation by standardized completion,ideological implementation by education and training ,the implementation of standards by inspection and monitoring and finally form a team by enhanced communication .Results The technicalstandards of hospital infection management was implemented and the quality of hospital infection control was improved progressively .Conclusion It is an effective way to guarantee medical security to improve the execution of the technical standard of hospital infec -tion management .
3.Application and development of translational medicine in modern acupuncture and moxibustion.
Chinese Acupuncture & Moxibustion 2014;34(5):503-507
In recent years, translational medicine, which is characterized by advanced concepts and methods, developes rapidly and playes a strategic role in the development of TCM acupuncture and moxibustion. Therefore, it is worth studying by acupuncturists. Through the background, development, features and research model of translational medicine, the present situation and problems of TCM acupuncture research are analyzed. Several cases of translational Chinese medicine and acupuncture are listed with the consideration of the concept of translational medicine. Studies and thoughts on translational acupuncture are expounded as well. Thus, it is suggested that combined with characteristics of acupuncture, the concept of translational medicine should be utilized to instruct the clinical treatment and research of acupuncture, foster researchers of translational medicine as well as establish the related research teams.
Acupuncture Therapy
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Humans
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Moxibustion
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Translational Medical Research
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4.Determination of five triterpenic acids from Salvia chinensis of different parts by RP-HPLC-PDA.
China Journal of Chinese Materia Medica 2014;39(22):4379-4382
OBJECTIVETo establish a RP-HPLC-PDA method for determination of five triterpenic acids (pomolic acid, hawthorn acid, corosolic acid, oleanolic acid and ursolic acid) in different parts of Salvia chinensis.
METHODThe isocratic elution and separation was achieved on a Kromasil C18 column (4.6 mm x 250 mm, 5 microm), using acetonitrile-water (90:10) as the mobile phase at a flow rate of 0.8 mL x min(-1). The detection wavelength and column temperature were set at 205 nm and 28 degrees C, respectively.
RESULTThe calibration curves of pomolic acid, hawthorn acid, corosolic acid, oleanolic acid and ursolic acid were linear over the ranges of 0.096 0-2.400, 0.1230-3.075, 0.2420-6.050, 0.2830-7.075 and 0.2730-6.825 microg (r = 0.9998, 0.9997, 0.9999, 0.9995, 0.9999), respectively. The average recoveries were 98.43%, 98.13%, 100.6%, 98.19% and 99.15%%, respectively, with RSD (n=6) being 1.3%, 0.67%, 1.2%, 0.87% and 0.43%.
CONCLUSIONThe proposed method is so simple and highly reproducible that it promises to be applicable for determination of major triterpenic acids in S. chinensis.
Chromatography, High Pressure Liquid ; methods ; Drugs, Chinese Herbal ; chemistry ; Plants, Medicinal ; chemistry ; Salvia ; chemistry ; Triterpenes ; chemistry
5.Emergency treatment of spontaneous frontotemporal intracerebral hematoma
Qin ZOU ; Xiaosheng YANG ; Xiaobing WU ; Yunlong ZOU ; Wenren YANG
Chinese Journal of Postgraduates of Medicine 2014;37(11):36-38
Objective To investigate the emergency treatment measures of spontaneous frontotemporal intracerebral hematoma.Methods Retrospectively analyzed the rescue process and surgical experiences of 27 patients with spontaneous frontotemporal intracerebral hematoma combined with subarachnoid hemorrhage or ventricular hemorrhage.Twenty-three cases underwent surgery;4 cases with cerebral hernia under general anesthesia underwent craniotomy hematoma clearance,aneurysm clip and decompressive craniectomy;7 cases with previous history of hypertension,considered with hypertensive intracerebral hemorrhage,was performed with craniotomy hematoma clearance and decompressive craniectomy in the emergency under general anesthesia; 12 cases of middle cerebral artery aneurysms bleeding,chosen craniotomy hematoma clearance and aneurysm clip;4 cases found nothing by digital subtraction angiography (DSA) or CT angiography (CTA),were given conservative treatment,one of them was found arteriovenous malformations after 1 month,which was treated by γ-ray.Results After the surgery,2 cases died due to severe cerebral infarction,25 cases were followed up for 6 months,according to the Glasgow outcome scale(GOS) classification:17 cases with good prognosis,7 cases with poor prognosis,1 case with vegetative state.Conclusions Cerebral hernia formation in patients with spontaneous frontotemporal intracerebral hematoma should relieve cerebral hernia and mass effect as soon as possible,early surgery to save lives.Which of them without brain hernia,after diagnosis by CTA or DSA,choice suitable treatment.Sufficient preoperative evaluation,suitable surgical timing and good microsurgical techniques can improve the prognosis.
8.Opinion on informed consent in clinical medical research
Xun ZHANG ; Haiying WANG ; Qin ZOU
Chinese Journal of Medical Science Research Management 2008;21(2):73-75
By reviewing the practice of informed consent,the authors analyzed the elements,forms of informing and consent,main parts,contents,informing process,signing,and saving of the informed consent and put forward some suggestions which are useful for the medical scientific resesxchers and management personnel.
9.Clinical analysis on 624 elderly patients with acute kidney injury
Qin ZOU ; Xiangping LIAO ; Shenggen GUO
Chinese Journal of Geriatrics 2012;31(9):786-788
Objective To investigate the pathogens,clinical characteristic and therapeutic method of acute kidney injury(AKI) Methods The morbidity,composition of pathogeny,staging and prognosis of 624 cases with AKI recruited by our department from January 1999 to December 2009,to evaluate the impacts of possible predisposing factors.Results The mortality rate of AKI was 19.6%(122/624),The mortality in the staging of exhaustion,damage,risk were 37.8%,33.4% and 6.7%,respectively.Of the 624 patients there were 21 cases (3.4%) discharged due to exacerbation,29 cases (4.7%) maintained the status quo,and 452 cases (72.4%) cured or improved;Among 138 patients with blood purification there vere 116 cascs(84.1 %)cured or improved and 22 cases (90.9%) with long term blood purification cured or improved.The pathogenyof the non-elderly group (<60 years old)were original diseases and collapse,and the pathogeny of the elderly group (≥60 years old)were original diseases.Conclusions AKI is serious with high incidence and mortality in hospitalized patients.The efficacy of long-term blood purification is better than common treatment.Early prevention,early diagnosis and active intervention will help to increase survival rate of AKI aud improve prognosis.
10.Regulatory roles of microRNA in intestinal barrier dysfunction-associated diseases
Yongzhi YANG ; Yang ZOU ; Huanlong QIN
Chinese Journal of Clinical Nutrition 2012;20(1):33-38
MicroRNAs (miRNAs) are a group of small (about 22 nucleotides),endogenous,noncoding RNAs that direct mRNA degradation and translational inhibition post-transcriptionally by binding to complementary sequences in the 3' untranslated regions of specific target mRNAs.miRNAs play multiple important roles in the intestinal epithelium,influencing a number of intestinal disease processes.This review summarizes the regulatory roles of miRNA in intestinal epithelial differentiation,architecture,membrane permeability,immunological function,and more importantly,the intestinal mucosal barrier dysfunction-associated diseases.