Parents and family background cast important influence on children's attachment style. Studies have consistently showed positive relations between maternal sensitivity and infant attachment security. Warm and harmonious family was also found to be an important factor. On the contrary, parents' poor marital status and high level of stress in family would result in insecure attachment style in children.

Magnetic resonance imaging (MRI),a commonly used imaging technique,has been extensively investigated in lung cancer diagnosis and staging.Many studies have demonstrated that MRI can be used for the differential diagnosis of benign and malignant pulmonary nodules and for the screening of lung cancer; it also has important value in TNM staging of non-small cell lung cancer (NSCLC),with equivalent sensitivity and specificity to 18F-fluorodeoxyglucose (18F-FDG) PET-CT,which suggests that MRI can be used as an alternative imaging modality in noninvasive diagnosis and staging of NSCLC.

The knowledge atlas for researches of invisible knowledge management was plotted after the key words and their relationship in papers on invisible knowledge published in the past 5 years were quantitatively and qualitatively analyzed by social network analysis, co-words cluster analysis, and impact factor analysis with the journal articles covered in CNKI, Wanfang, VIP Chinese Scientific and Technological Journals Databases as the data source.The hotspots and structure in researches of invisible knowledge management were then studied in order to provide reference for the innovative development and future research of invisible knowledge management.

Autistic Disorder ; epidemiology ; Child ; Child, Preschool ; Comorbidity ; trends ; Epilepsy ; epidemiology ; Female ; Humans ; Male

Animals ; Cytokines ; physiology ; Humans ; Immune System ; drug effects ; physiology ; Melatonin ; pharmacology ; Opioid Peptides ; physiology ; Receptors, Melatonin ; physiology ; Stress, Physiological ; immunology ; T-Lymphocytes ; drug effects ; physiology

Objective To investigate the quality control and standardization of HE and immunohistochemical stainings in tissues slice.Methods In accordance with the standardization of quality control,HE and immunohistochemial stainings in tissues slice were performed,and the results were blindly compared before and after the standardization.Results The excellent rates of HE and immunohistochemical stainings in tissues slice after standardization were 92.3％ and 91.1％ respectively,and higher than those before standardization 78.9％ and 74.9％(x2 =3.841,3.801,all P ＜ 0.05); Diagnosis rate of 100 cases with liver biopsy tissue after standardization 86.0％ was significantly higher than 73.0％ before standardization(x2 =3.741,P ＜ 0.05).Conclusion The quality of HE and immunohistochemical stainings in tissues slice enhanced after standardization.

Objective To investigate the changes of serum hs-CRP、ET、MMP-9 and NSE levels and the relationships with neurological function defect in acute cerebral infarction patients,and the influence of edaravone on it.Methods 100 patients with acute cerebral infarction were randomly divided into routine group and edaravone group,the routine group were given routine treatment,the edaravone group were added edaravone 30mg,twice a day,total of 14d;the serum levels of hs-CRP、ET、MMP-9 and NSE and the change of neural function defect were investigated before treatment and 14d after treatment.Results The serum levels of hs-CRP,ET,MMP-9 and NSE were in a positive correlation with the score of neurological function defect(P ＜ 0.05).The edaravone group serum levels of hs-CRP,ET,MMP-9 and NSE were lower than those of routine group in invasion after treatment(P ＜ 0.05).Score of NIHSS in the trial group was lower than that of routine group(P ＜ 0.05).Conclusion The serum levels of hs-CRP,ET,MMP-9 and NSE increase in the patients with acute cerebral infraction.Edaravone can reduce the serum hs-CRP,ET,MMP-9 and NSE levels and promote the recovery of neurological function in patients with acute cerebral infarction.

The development of science and technology dramatically promotes the application of minimally invasive technique in the field of gastrointestinal surgery.Today,almost all kinds of gastrointestinal operations can be accomplished through or with the assistance of a laparoscope.Compared to traditional open surgery,lapm'oscopic surgery,which is accomplished by experienced surgeons.can leads to a similar or even better surgical outcome.Although the endoscopic technique was firstly invented as a diagnostic method,its application has expanded to many different medical areas.Now,endoscopic gastrointestinal polypectomy is extensively applied in primary hospitals.Moreover,endoscopic mucosal resection and endoscopic submucosal dissection are also ca~ied out in many large medical centers in China.More and more patients are benefiting a lot from the minimally invasive technique.As the concept of minimally invasive technique is widely accepted,minimally invasive surgery will be a major aspect in the development of gastrointestinal surgery.As a contemporary gastrointestinal surgeon,it is imperative to handle the minimally invasive technique proficiently.

Objective To investigate the application of continuous renal replacement therapy in critically ill patients and clinical nursing measures.Methods 100 critically ill patients receiving continuous renal replacement therapy were chosen from October 2009 to June 2011 in our hospital and were given nursing intervention.The biochemical indicators before and after treatment were compared and analyzed.Results The biochemical indicators in patients improved significantly after continuous renal replacement therapy.There was significant difference.Conclusions Effective and comprehensive nursing for critically ill patients in continuous renal replacement therapy can improve the patients vital signs,improve the survival rate of them,and it should be carried out in clinic.

ObjectiveTo explore the current occurrence of upper gastrointestinal bleeding in elderly patients in our hospital and its possible risk factors and treatment program.MethodsAn observational prospective analysis of medical records of 758 consecutive patients was performed.Clinical presentation,etiology and treatment were evaluated.The follow-up ended on the dates of a first occurrence of UGIB,stopping co-therapy,death or 6 months after admitted in the group.Results426 male and 332 female were admitted in the group,UGIB occurred in 48 patients.PPI,H2RA,gastric mucosa protectant plus PPI,gastric mucosa protectant plus H2RA and control were prescribed in 108,240,70,102,238 patients respectively.There were statistics difference in each group compared with control in bleeding rate.ConclusionThe occurrence of UGIB associated with A + C co-therapy in elderly was 6.3％.Co-prescription with PPI and gastric mucosa protectant was associated with a lower risk.