Parents and family background cast important influence on children's attachment style. Studies have consistently showed positive relations between maternal sensitivity and infant attachment security. Warm and harmonious family was also found to be an important factor. On the contrary, parents' poor marital status and high level of stress in family would result in insecure attachment style in children.

Magnetic resonance imaging (MRI),a commonly used imaging technique,has been extensively investigated in lung cancer diagnosis and staging.Many studies have demonstrated that MRI can be used for the differential diagnosis of benign and malignant pulmonary nodules and for the screening of lung cancer; it also has important value in TNM staging of non-small cell lung cancer (NSCLC),with equivalent sensitivity and specificity to 18F-fluorodeoxyglucose (18F-FDG) PET-CT,which suggests that MRI can be used as an alternative imaging modality in noninvasive diagnosis and staging of NSCLC.

The knowledge atlas for researches of invisible knowledge management was plotted after the key words and their relationship in papers on invisible knowledge published in the past 5 years were quantitatively and qualitatively analyzed by social network analysis, co-words cluster analysis, and impact factor analysis with the journal articles covered in CNKI, Wanfang, VIP Chinese Scientific and Technological Journals Databases as the data source.The hotspots and structure in researches of invisible knowledge management were then studied in order to provide reference for the innovative development and future research of invisible knowledge management.

P-glycoprotein(P-gp),the product of multidrug resistance gene MDR1,plays a very significant role in the ADME processes(absorption,distribution,metabolism,excretion)and drug-drug interaction of drugs in human.The magnitude of resistance depends on the expression of MDR1 up-regulated by chemotherapy.DNA sequence differences ale associated with phenotypic variation by various mechanisms,single-nucleotide polymorphisms(SNPs)is the most common of them.Genetic polymorphisms of MDR1 are associated with alteration in P-gp expression and function in different ethnicities and subjects.

Objective To investigate the high frequency ultrasonic wave features of mucocele of the appendix,and to improve the diagnostic ability of the disease. Methods All 7 patients with mucocele of the appendix were confirmed by pathology and surgery. High frequency ultrasonic wave findings were analyzed retrospectively. Resuits The high frequency wltrasonic wave demonstrated a mass of low attenuation in the right lower quadrant in all 7 cases. The masses were either spherical( n = 2) or elongated ( n = 5) in shape. Two masses had mural calcification,and 4 had mural enhancement after contrast enhancement. The mueocele inside full liquid was a homogeneous cystic mass in 3 cases,cystic mass with internal septations in 1 case,and cystic mass with peripheral solid tissue in 1 case.Conclusion The high frequency ultrasonic wave scan is a useful method in differential diagnosis mucocele of the appendix.

Objective To obtain antibody mother by means of having have an inoculation the measles vaccine to our area,The measles antibody after the embryo passed on to infant is living 0～8 monthly age degree of the dripping level examines;to find out such antibody attenuation regular pattern, forecast such antibody disappearance time and to probe into fitly start dispenses with monthly age. Methods Adopts ELISA's means to ascertain by measuring in the serum measles IgG's antibody level. Results Killing to adjust 65 instances infant embryoes passes on that antibody the traceing observation discovers,Newborn baby's antibody is levd 83%,3 monthly age hour drops till 46.15%;6 monthly age hour drops till 10.77%;8 monthly age drops till 7.67%. 6 Monthly age queen's antibody level exceedingly lets drop, nearly unprotect action. Conclusion Illustrates the infant embryo passes on antibody sharply droping with the monthly age increase;6 Monthly age queen's easy infection rate is high to 93.22%; In the interest of the utmost safeguards infant to dispense with contracting by the measlas,may consider haves an inoculation currently in effecting 8 monthly age measles vaccine ahead of time till is born 5-6 monthly age.

COX-2 and tumor are closely related.Pre-clinical studies have shown that the selective COX-2 inhibitor can strengthen the tumor radiation sensitivity function and chemotherapy medicine anti-tumor activeness,selective COX-2 inhibitor may provide new method and way for tumor prevention and treatment.

Objective:To understand the effect and significance of rehabilitation nursing of the patients with total hip replacement. Method:In view of the rehabilitation nursing procedure, functional training before and after the operation were performed in 34 cases with total hip replacement. Result:21 cases made completely recovery; 9 cases complete independent living ;3 cases almost independent living; l case partial dependent, and no complications. Conclusion: Scientific rehabilitation nursing plan can decrease the incidence rate of complications after the operation and promotes functional recover to patients with total hip replacement.

To help pharmaceutical companies absorb lessons from the Ban on PPA, the article analyses the behavior of SinoUS Smith Kline & French, which led to great loss after the Ban of an PPA by SDA of China. It points out that the Ban of PPA did not come unexpectedly. Before the Ban many clinical reports had been released and the authorities of some countries had already introduced ban on PPA or issued warnings on the possible danger of PPA. If the company in question had taken timely measures to keep track of the information, the loss could have been minimized, It is concluded that the pharmaceutical companies should step up their effort for the monitoring and following-up of their products after introduction of their durgs to markets and attach importance to the study of pharmacoepidemioloy. Pharmaceutical companies should put emphasis on the collection of information.

ObjectiveTo explore the current occurrence of upper gastrointestinal bleeding in elderly patients in our hospital and its possible risk factors and treatment program.MethodsAn observational prospective analysis of medical records of 758 consecutive patients was performed.Clinical presentation,etiology and treatment were evaluated.The follow-up ended on the dates of a first occurrence of UGIB,stopping co-therapy,death or 6 months after admitted in the group.Results426 male and 332 female were admitted in the group,UGIB occurred in 48 patients.PPI,H2RA,gastric mucosa protectant plus PPI,gastric mucosa protectant plus H2RA and control were prescribed in 108,240,70,102,238 patients respectively.There were statistics difference in each group compared with control in bleeding rate.ConclusionThe occurrence of UGIB associated with A + C co-therapy in elderly was 6.3％.Co-prescription with PPI and gastric mucosa protectant was associated with a lower risk.