目的探讨实施社保医疗后肺部感染患者的治疗效果与费用。方法随机选择肺部感染的住院患者60例(社保组30例,非社保组30例),社保组根据社保文件精神对患者进行检查治疗,非社保组仍按以往治疗方案并结合患者意愿进行检查治疗,分析两组的疗效与费用。结果社保组的肺部感染住院患者总的直接医疗费用平均为(1540.73±991.43)元,非社保组为 (2232.02±844.98)元;总医疗费用社保组平均为(1716.65±1028.33)元,非社保组为(2653.89±966.39)元;住院天数社保组平均为(11.8±6.42)天,非社保组为(15.3±4.71)天 ,社保组总的医疗费用显著低于对照组(P<0.001),但疗效无显著性差异。结论实施社保医疗可在有效降低肺部感染患者总的医疗费用的同时,保证疗效,真正把有限的医疗资源用在需要的患者身上。

OBJECTIVE:To analyse the advantages and disvantages of split tablets given to in-patients.METHODS:We collected13kinds of oral tablets(10tablets each kind and260pieces of the split tablet altogether),which were often splitted by pharmaceutists.We tested and analysed the weight variation of the split tablet on the basis of the dosage consistency metioned in the USP which is applied to the whole tablet.RESULTS:None of the13kinds of prescription drug passed the consistent testing after splitting.There was some relationship between the effect of the split tablet and its shape.It was relatively easy to break off the tablet with nick in half.The loss of dosage inevitably occurred during the process of splitting the tablet.CONCLUSION:Breaking off the tablet in half led to high ratio of weight variation.The modus operandi of splitting the tablet in half for saving expenses can only be applied to those drugs with low toxicities and relatively flat dose-effect curve.In the case of those drugs which bear high toxicities and steep dose-effect curve,carefulness should always be taken when applying such method.

The paper introduces the ideas of designing hospital information system, including comprehensive cabling, network cover-age, ward calling system, ward monitoring system, queuing management, media teaching, multi -function hall, digital meeting and se-curity system, which would provide reference for the designing and implementation of hospital information system.

To identify the expression of the molecule recognized by Pf18-3 mAb (Pf18-3 molecule) on various cells. Meth-ods: The expression of pr18-3 molecule was assayed by flow cytometry and confocal laser scanning microscope . Result: The molecule recog-nized by Pf18-3 mAb expressed on TSC and other stromal cells. Whereas, fresh thymocytes were Pf18-3 negative. Interestingly, the expressionof Pf18-3 molecule was gradually up-regulated on thymocytes after activation by ConA. This molecule mainly expressed on CD4+ CD8+ andCD4+ CD8- cells. Under confocal laser scanning microscope, the staining of fluorescence showed as ring around the cell, it changed grsduallystronger and thicker with activation. Conclusion: This study indicated that the Pf18-3 molecule was co-expressive molecule of MTSC and acti-vated tlymocytes,it was concemed closely about the activation of CD4+ C D8+ and CD4+ CD8- cells.

Objectives: To research the effects of recombinant human growth hormone on hypoproteinemia after severe head injury. Methods: Thirty six patients with hypoproteinemia after severe head injury were randomized into study group and control group. In study group, the rhGH was administered subcutaneously in the dose of 8 U every day for 7～10 days. Serum albumin, prealbumin and transferin were determined in 5 days and 10 days after giving rhGH. Results: The serum albumin, prealbumin and transferin were increased obviously in study group. Conclusions: rhGH can effectively correct hypoproteinemia after severe head injury.

本文报告52例Ⅰ～Ⅱ期高血压病患者在常规治疗的同时，采用饮食、心理、教育、运动、调息等康复措施进行系统康复医疗。出院后长期接受康复指导，每1～3个月于专科门诊诊查一次，每年系统复查1～2次。同期与25例条件相同单纯采用常规治疗的高血压病患者作对照。至今5～7年。结果显示：康复医疗组患者疗效明显优于对照组。

Objective To establish the triplex Taqman probes real-time RT-PCR method for simultaneously detecting of EV71,CA16 and EV.Methods Retrospective study.Specific primers and probes were designed based on conserved regions of EV71,CA16 and EV.The sensitivity,specificity and reproducibility were assessed by the optimized reaction system.A total of 176 throat swabs as the experimental group were collected from children with suspected hand foot mouth disease (HFMD),who admitted from April 2012 to July 2012 in Nanjing Children's Hospital affiliated to Nanjing Medical University.During this time,10 cases of healthy children,10 cases of outpatients with flu-like symptoms and 90 cases of inpatients in pneumology department of our hospital were recruited as control group,whose throat swabs were also collected.All of 286 samples were tested by the triplex Taqman probes real-time RT-PCR for simultaneously detecting EV71,CA16 and EV.SPSS13.0 was used to analyze the results.Results The sensitivities of the triplex Taqman probes real-time RT-PCR was 1.0 × 103 copies per milliliter for EV71,CA16 and EV.It showed 100％ specificity for 9 enterovirus and 3 non-enterovirus.Analysis with 1.0 × 103-1.0 × 105 copies per milliliter constructed plasmids demonstrated high reproducibility with coefficient of variation of 0.44％-1.04％ for EV71,0.38％-0.73％ for CA16,and 0.46％-0.90％ for EV.More over 176 samples collected from children with suspected HFMD were detected by triplex Taqman probes real-time RTPCR and real-time RT-PCR.The results showed 97.2％ (171/176)agreement and 0.94 Kappa value with high concordance.Conclusions The triplex Taqman probes real-time RT-PCR detecting EV71,CA16 and EV simultaneously has been established successfully.The assay,with high sensitivity and specificity,provide good basis for the rapid clinical diagnosis of EV71,CA16 and EV and open up broad prospects for clinical and relevant researches.

ObjectiveTo investigate the prognostic factors of non-small cell lung cancer (NSCLC) after resection.MethodsClinical data of 131 NSCLC patients who underwent resection were reviewed and divided into chemotherapy group(86 cases) and non-chemotherapy group(45 cases) according to the treatment method.Survival rate was calculated by Kaplan-Meier method.The prognosis was analyzed by Cox proportional hazards model.ResultsThe median survival time (MST) of squamous cell carcinoma (76 cases),bronchial alveolar cell carcinoma( 8 cases),adenocarcinoma( 35 cases ),adenosquamous carcinoma (12 cases) was 60,54,34,24 months respectively (P＜0.05).For the patients of stage Ⅰ B,the MST of chemotherapy group and non-chemotherapy group was 75 and 76 months respectively(P ＞ 0.05 ).Multivariate analysis showed that tumor size,T stage,N stage,chemotherapy were independent prognostic factors (P =0.080,0.002,0.000,0.029).Conclusions Squamous cell carcinoma and bronchial alveolar cell carcinoma have better prognosis than adenocarcinoma,adenosquamous carcinoma.For the patients of stage Ⅰ B,the survival time can't be prolonged through platinum-based chemotherapy.Tumor size,T stage,N stage,chemotherapy are independent prognostic factors.

Acute obstructive suppurative cholangitis (AOSC) is one of the most serious acute abdomen.The incidence of abdominal infection is significantly improved when patients were complicated with AOSC and diabetes mellitus,and then bile leakage,intestinal fistula and even death were induced by abdominal infection.The management of abdominal infection is very important for the prognosis of patients.One patient with AOSC and diabetes mellitus was admitted to the No.425 Hospital of PLA from May to July in 2013.Recurrent abdominal infection and abscess occurred after the operation due to his family members' refusal of surgery at early period and lax control of blood glucose before and after surgery,and then bile leakage and intestinal fistula were induced.The patient underwent operation for 3 times,and was cured after receiving fasting,gastrointestinal decompression,parental nutrition,somatostatin administration and antibiotic treatment.