1.Treatment of 135 patients with malignant astrocytoma
Yu LI ; Qihe TIAN ; Fentong WU
Chinese Journal of Radiation Oncology 1992;0(01):-
Purpose: To analyze the treatment effects by radiotherapy alone and radiotherapy plus chemotherapy of carotid artery intubation after operation for malignant astrocytoma. Materials and Methods: 135 patients with malignant astrocytoma were treated from August, 1987 to November, 1992. Patients were divided into two groups after operation: 71 patients received radiotherapy alone and 64 patients,combination therapy of chemotherapy (BCNU) plus radiotherapy. All patients received DT 55~70Gy. In combination therapy group, BCNU(250mg) was given daily by carotid artery intubation for 4~15 days.Radiotherapy was given 10~15 days after chemotherapy, then followed by 1~3 intubation. Results: The median survival were 17.5 months in radiotherapy alone group and 31.9 months in combination one.Patients with glioblastoma gave the better results with the 2-,3-,and 5- year survivals of 70%, 36% and 15%, respectively. Conclusion: Chemotherapy (BCNU) of intubation plus radiotherapy is preferable in treating malignant astrocytoma after operation.
2.Effect of variable hip abduction orthosis on children spastic cerebral palsy
Wei-hong WU ; Xiao-ping YUN ; Xue-yan HU ; Qihe CUI
Chinese Journal of Rehabilitation Theory and Practice 2004;10(9):547-548
ObjectiveTo explore the effect of variable hip abduction orthosis on children spastic cerebral palsy.Methods5 children with spastic diplegia cerebral palsy had used variable hip abduction orthosis to correct scissors gait which remained after rehabilitation. The stepping of 5 children was assessed with a gait analysis system base on digital video and image processing which could provide distance rate between knees and hips(K/I) in gait phase. One year Follow up was carried out.ResultsThere was significant difference on K/I before and after using variable hip abduction orthorsis (P<0.05).ConclusionThe variable hip abduction orthorsis can inhibit adductor muscles convulsion, improve model kinesis of scissors gait and stabilize stepping.
3.Research on the Clinical Usage of Orthosis
Yingyuan HU ; Huisan ZHAO ; Qihe CUI ; Jifeng ZHAO ; Ming YANG ; Yanchun LI ; Weihong WU ; Huabao LU
Chinese Journal of Rehabilitation Theory and Practice 1999;5(2):66-68
This research focused on the rehabilitation effect of orthosis for cerebral palsy(CP) children.46 CP children with physical dysfunction used the orthosis as an auxiliary therapy.The gait analysis,equilibrium,and comprehensive ADL measurement had been administrated pretherapy and post-therapy.The results show that 94.25% of CP children had improved their functions.The conclusions of this study indicated that it is important to use orthosis as an auxiliary therapy for CP children.Some important items of therapy had been discussed and the experiences of making plastic AFO had been introduced.
4.Clinical observation of methimazole combined with Selenious in the treatment of hyperthyroidism
Shuoliang LI ; Xiujuan FENG ; Qihe WU ; Huaping HE ; Meiyan HE ; Ruizhu TAN ; Hongju LEI
Chinese Journal of Primary Medicine and Pharmacy 2018;25(6):692-695
Objective To assess the efficacy and safety of methimazole combined with selenium therapy in the treatment of hyperthyroidism .Methods 130 cases with hyperthyroidism were selected , and according to the digital table they were randomly divided into methimazole plus selenium treatment group ( ATD +Se group ) and methimazole treatment group(ATD group),65 cases in each group.The patients were followed up for 3 months.The thyroid function index and thyroid antibody index were observed before and after treatment .The adverse reactions were observed,too.Results After treatment,the serum levels of FT3,FT4,TSH in the ATD +Se group were (3.32 ± 0.53)pg/mL,(1.02 ±0.17)ng/dL,(2.72 ±0.32)mIU/L,respectively,which in the ATD group were (4.82 ± 0.75)pg/mL,(2.41 ±0.32)ng/dL,(2.72 ±0.32)mIU/L,respectively.The change ranges of the ATD +Se group were better than those of the ATD group ,the differences were statistically significant (t=4.591,3.814,3.567,all P<0.05).The TPOAb,TGAb,TRAb in the ATD+Se group were (120.3 ±23.1) IU/mL,(123.3 ±26.5) IU/mL, (1.72 ±0.89)IU/mL,respectively,which in the ATD group were (132.8 ±21.1)IU/mL,(134.8 ±21.3)IU/mL, (3.68 ±1.06)IU/mL,respectively.The changes of the ATD+Se group were more significant than those of the ATD group,the differences were statistically significant (t=4.291,3.514,3.767,all P<0.05 ).The total effective rate of the ATD+Se group was higher than that of the ATD group (90.77%vs.76.92%χ2 =13.147,P<0.05 ).The incidence rate of adverse reactions in the ATD +Se group was lower than that in the ATD group (12.31%vs.27.69%χ2 =18.685,P<0.05 ).Conclusion The results suggest that methimazole combined with selenium treatment is effective and safe for hyperthyroidism .