Objective To establish the quality standard of Shilong Qingxue Effervescent Granules. Method Rhizoma curcuma, flos sophorae, cornus officinalis and gamdir vine in Shilong Qingxue Effervescent Granules were identified by TLC. The content of gastrodin in Shilong Qingxue Effervescent Granules was determined by HPLC. Results The TLC spots were highly clear without the interference of negative samples and were reproductive. A good linear for gastrodin was in the range of 14～70 ?g/mL (r=0.999 9). The average recovery was 97.33% (RSD=0.63%). Conclusion This method is simple, rapid and accurate, and can be used for the quality control of Shilong Qingxue Effervescent Granules.

OBJECTIVE: To establish the quality standard of Liuweiluhui ointment. METHODS:Phizoma Coptidis,Rhizoma Et Radix Polygoni Cuspidati and Aloe in Liuweiluhui ointment were identified qualitatively by TLC. The content of Aloe-emodin in Liuweiluhui ointment was determined by HPLC. RESULTS: The TLC spots were clear and specific yet without the interference of negative samples. The linear range of Aloe-emodin was 1～20 ?g?mL-1(r=0.999 7). The average recovery was 95.94%(RSD=1.1%,n=6). CONCLUSION: The established standard is suitable for the quality control of Liuweiluhui ointment.

OBJECTIVE:To establish the quality standard of Compound Yiganling dropping pills.METHODS:Fructus Silybi and Fructus Schisandrae Chinensis were identified by TLC.The content of Silybin was determined by HPLC.RESULTS:The qualitative identification was of high resolution and free of interference of negative substance.The linear ranges of Silybin was 0.09～0.54 mg?mL-1,and the average recovery was 97.38%(RSD=1.19%,n=6).CONCLUSION:The method can be used for the quality control of Compound Yiganling dropping pills.

Traumatic cerebrospinal fluid leakage commonly presents in traumatic brain injury patients, and it may lead to complications such as meningitis, ventriculitis, brain abscess, subdural hematoma or tension pneumocephalus. When misdiagnosed or inappropriately treated, traumatic cerebrospinal fluid leakage may result in severe complications and may be life-threatening. Some traumatic cerebrospinal fluid leakage has concealed manifestations and is prone to misdiagnosis. Due to different sites and mechanisms of trauma and degree of cerebrospinal fluid leak, treatments for traumatic cerebrospinal fluid leakage varies greatly. Hence, the Craniocerebral Trauma Professional Group of Neurosurgery Branch of Chinese Medical Association and the Neurological Injury Professional Group of Trauma Branch of Chinese Medical Association organized relevant experts to formulate the " Chinese expert consensus on the diagnosis and treatment of traumatic cerebrospinal fluid leakage in adults ( version 2023)" based on existing clinical evidence and experience. The consensus consisted of 16 recommendations, covering the leakage diagnosis, localization, treatments, and intracranial infection prevention, so as to standardize the diagnosis and treatment of traumatic cerebrospinal fluid leakage and improve the overall prognosis of the patients.

The condition of patients with severe traumatic brain injury (sTBI) complicated by corona virus 2019 disease (COVID-19) is complex. sTBI can significantly increase the probability of COVID-19 developing into severe or critical stage, while COVID-19 can also increase the surgical risk of sTBI and the severity of postoperative lung lesions. There are many contradictions in the treatment process, which brings difficulties to the clinical treatment of such patients. Up to now, there are few clinical studies and therapeutic norms relevant to sTBI complicated by COVID-19. In order to standardize the clinical treatment of such patients, Critical Care Medicine Branch of China International Exchange and Promotive Association for Medical and Healthcare and Editorial Board of Chinese Journal of Trauma organized relevant experts to formulate the Chinese expert consensus on clinical treatment of adult patients with severe traumatic brain injury complicated by corona virus infection 2019 ( version 2023) based on the joint prevention and control mechanism scheme of the State Council and domestic and foreign literatures on sTBI and COVID-19 in the past 3 years of the international epidemic. Fifteen recommendations focused on emergency treatment, emergency surgery and comprehensive management were put forward to provide a guidance for the diagnosis and treatment of sTBI complicated by COVID-19.