Objective To investigate the effectiveness of transtheoretical model of behavior change in the intervention of childhood obesity. Methods Randomized sampling method was used to select experiment schools and control schools for physical examination from October 2012 to June 2014. The overweight and obesity students of the experiment schools were intervened with the transtheoretical model of behavior change. The authors evaluated the obesity students′ knowledge about the intervention of obesity, healthy behavior methods compliance, and weight control qualified rate. Results Before the intervention, the obesity rate, BMI of overweight students, skinfold thickness, blood glucose and blood lipid had no significant differences between the two groups (P>0. 05). After the intervention, the BMI and skinfold thickness in the experiment group were (27. 7 ± 3. 6) kg/m2 and (21. 7 ± 4. 3)mm, which were significantly better than those in the control group (t=3. 674, 4. 029, respectively;P<0. 05). The blood glucose, total cholesterol, triglyceride,high and low density lipoprotein in the experiment group were(5. 17 ± 0. 8), (3. 47 ± 0. 6), (0. 73 ± 0. 3), (1. 14 ± 0. 1) and (1. 53 ± 0. 2) respectively, which were significantly better than those in the control group ( t=3. 437, 4. 257, 3. 478, 2. 206,3. 759, respectively;P <0. 05). The knowledge of obesity, healthy behavior adherence and weight control rate in the experiment group were significantly better than those in the control group (P<0. 05). Conclusions The application of tanstheoretical model of behavior change for nursing intervention and prevention has a prosperous future for getting the overweight and obesity student to have more knowledge about obesity, enhance the healthy behavior methods compliance, and increase the rate of weight qualified.

Objective To evaluate the efficacy and safety of Elvitegravir, Cobicistat, Emtricitabine and Tenofovir Alafenamide Fumarate Tablets in initial treatment of acquired immune deficiency syndrome (AIDS) patients. Methods A total of 80 treatment-naive AIDS patients were selected as research subjects and randomly divided into control group and observation group, with 40 patients in each group. The control group was treated with free antiviral drugs (tenofovir + lamivudine + efavirenz), while the observation group was treated with Elvitegravir, Cobicistat, Emtricitabine and Tenofovir Alafenamide Fumarate Tablets. The CD4⁺ count, human immunodeficiency virus (HIV) viral load, and biochemical indicators were compared between the two groups before treatment and at 3, 6, 9, and 12 months after treatment. The adherence, adverse reactions, and quality of life were also compared between the two groups. Results During the treatment, six patients in the observation group and 9 patients in the control group had no compliance. With the extension of treatment time, the CD4⁺ level in both groups gradually increased, and the HIV viral load gradually decreased (P < 0.05). After 3, 6, 9, and 12 months of treatment, the CD4⁺ levels in the observation group were higher than those in the control group, and the HIV viral loads were lower than those in the control group (P < 0.05). With the extension of treatment time, the levels of alanine aminotransferase, aspartate aminotransferase, urea, creatinine, and uric acid in the control group gradually increased, and the random blood glucose levels after 3, 6, 9, and 12 months of treatment in the control group were higher than those before treatment (P < 0.05). After 3, 6, 9, and 12 months of treatment, the levels of alanine aminotransferase, aspartate aminotransferase, urea, creatinine, uric acid, and random blood glucose in the observation group were lower than those in the control group (P < 0.05). The incidence of adverse reactions in the observation group was 2.94% (1/34), which was lower than 90.00% (36/40) in the control group (corrected χ²=55.718, P < 0.001). With the extension of treatment time, the scores of various dimensions of quality of life in both groups gradually increased, and the scores of various dimensions of quality of life after treatment in the observation group were higher than those in the control group (P < 0.05). Conclusion Compared with the free antiviral drug regimen, Elvitegravir, Cobicistat, Emtricitabine and Tenofovir Alafenamide Fumarate Tablets shows better efficacy in the treatment of AIDS-naive patients, which can significantly increase the CD4⁺ level, and reduce the HIV viral load. Besides, it has high safety, and can significantly improve their quality of life.

Objective To estimate the curative effect of non-gastrointestinal decompression in laproscopic colorectal surgery. Methods By using the single-blind-random test and prospective study, 55 patients were divided into two groups, experimental group and matched group. The difference of operating time, gastrointestinal function recovery time, adverse effect, complication, average length of hospital stay between two groups were observed and evaluated. Results The difference of operating time, gastrointestinal function recovery time, adverse effect, complication, average length of hospital stay between two groups were not statistically significant(P>0.05). The incidence rate of sore throat and cough and expectoration difficulty after operation was significantly lower in the experimental group (the rate was respectively 16.0% vs 77.7% and 8.0% vs 50.0, P<0.05). However, The incidence rate of nausea and vomiting, abdom-inal distension was not statistically significant(P>0.05). Conclusion In the perioperative period of laproscopic colorectal surgery, non-gastrointestinal decompression appears to be security and feasible.