Objective:To evaluate the reliability and validity of Chinese version of Ureteral Stent-Related Symptom Questionnaire (USSQ) so as to provide a scientific tool for the symptom assessment of patients with indwelling ureteral stents.Methods:Following the translation principle of Brislin, the cultural adjustment of the questionnaire was completed according to the process of literal translation of the scale, back translation, expert committee discussion and pre-experiment, and the Chinese version of USSQ was formed. Inpatients with ureteral stents in the Urology Departments of 3 ClassⅢ Grade A hospitals in Urumqi from April 2018 to February 2019 were selected as research objects, and 485 questionnaires were collected by analyzing and testing the items and reliability and validity of the questionnaire.Results:Finally, 462 valid questionnaires were collected. The analysis results of the project suggested that the two items of S1 and S2 in the Chinese version of USSQ in the field of sexual life could be deleted ( P>0.05) , however, considering the rationality of the structure of the questionnaire, S1 should be retained. Cronbach's α coefficient of the questionnaire was 0.923, Cronbach's α coefficient of the six dimensions of urinary symptoms, physical pain, total health status, work performance, sexual life and additional problems was 0.703 to 0.918, retest reliability was 0.885, retest correlation coefficient of the six dimensions was 0.338 to 0.849 ( P<0.05) , and half reliability was 0.628. The content validity of the questionnaire was 0.887. Through exploratory factor analysis, the cumulative variance contribution rate of the nine principal factors was 68.995%. In the correlation analysis, except for the correlation coefficients in the field of sexual life and other fields were from 0.014 to 0.101 ( P>0.05) , the correlation coefficients in other dimensions were from 0.406 to 0.629 ( P<0.01) . The test results of criterion validity showed that the correlation coefficients of each dimension of the questionnaire with International Prostate Symptom Score (IPSS) , Incontinence Quality of Life Scale (I-QOL) and The 12-Item Short Form Health Survey (SF-12) were from 0.35 to 0.49 ( P<0.01) . Conclusions:In addition to the field of sexual life, the Chinese version of USSQ has good reliability and validity in the evaluation of symptoms in other fields, which can provide a basis for the investigation and improvement of related symptoms in patients with indwelling ureteral stents in China.