Objective:To analyze the predictive effect of tumor deposit(TD) on the prognosis of yp-stage Ⅲ rectal cancer patients, and its effect on postoperative adjuvant chemotherapy benefit.Methods:Clinical data of 338 ypⅢ stage rectal cancer patients who received multidisciplinary treatment in Union Medical College Affiliated Hospital of Fujian Medical University from 2007 to 2017 were retrospectively analyzed. All patients were divided into the TD(-) group( n=301) and TD(+ ) group( n=37). Survival analysis was conducted by Kaplan- Meier method, log-rank test and univariate prognostic analysis. Multivariate prognostic analysis was performed by Cox’s regression model. Results:The 5-year overall survival(OS), progress-free survival(PFS), and distant metastasis-free survival(DMFS) in the TD(-) group were significantly higher than those in the TD(+ ) group(59.3% vs. 42.0%, P=0.001, 79.1% vs. 55.0%, P<0.001, 55.6% vs. 38.0%, P<0.001), whereas no significant difference was observed in local recurrence-free survival(LRFS) between two groups(96.7% vs. 85.5%, P=0.679). Univariate prognostic analysis revealed that the number of TD was not correlated with the prognosis of patients( P=0.923), and postoperative adjuvant chemotherapy exerted no significant effect on the prognosis of patients in two groups( P=0.103). In multivariate analysis, TD was associated with worse OS( HR=2.343, 95% CI: 1.257-4.363, P=0.007). Conclusions:For patients with ypⅢ stage rectal cancer undergoing multidisciplinary treatment, the prognosis of patients with TD is even worse. TD is an independent predictor for survival. No benefit can be obtained from postoperative adjuvant chemotherapy regardless of the presence or absence of TD.

Objective To explore the effect of bellybutton exposure on premature navel nursing effect.Method Three hundred and ninety-three premature infants were randomly divided into experiment group(n=195)and control group(198). Bellybutton fasciation and bellybutton exposure were used in the control group and the experiment group respectively. The two groups were compared in terms of umbilical shedding,time of umbilical healing,umbilical swelling,bleeding and breathing.Result The umbilical healing time in the experiment group was significantly shorter than that of the control group(P<0.05). The incidences of omphalitis,umbilical swelling and bleeding, changed breathing in the experiment group were significantly lower than those of the control group(all P<0.05).Conclusion The bellybutton exposure is effective in promoting the umbilical shedding in premature infants and reducing the incidence rate of premature navel infection.

Objective To explore the effects of Kegel exercise combined with acupoint therapy on bladder function recovery in patients after the surgery of cervical carcinoma. Methods A total of 55 patients with cervical cancer who received laparoscopic radical hysterectomy, bilateral salpingooophorectomy and pelvic lymphadenectomy at Wuxi Maternity and Child Health Hospital from January 2014 to February 2016. Those patients were divided into control group (n=22, routine indwelling catheter nursing) and observation group (n=33, routine indwelling catheter nursing + Kegel exercise combined with acupoint therapy) according to admission time. The success rate of autonomous urination for the first time after removing catheter, the rate of failure to pull out the catheter,the rate with catheter at discharge and the time of indwelling catheter was compared between two groups. Results There were 13 patients with smoothly autonomous urination after removing catheter for the first time and 9 patients with catheter returning home in control group, while there were 31 patients with smoothly autonomous urination after removing catheter for the first time and one patients with catheter returning home in observation group with significant differences between two groups (χ2=10.02, 12.73; P<0.05). The average time of indwelling catheter was (452.00±246.54) h in observation group and (253.56±86.02) h in control group with a significant difference (t=2.63, P<0.05). Conclusions The Kegel exercise combined with acupoint therapy can obviously improve the bladder function recovery in patients after the surgery of cervical carcinoma.