Objective To investigate the relation of resistant index and function of transposited ovaries following radical hysterectomy in young women with early stage of cervical cancer.Methods A total of 22 young women(aged from 26 to 40 years old)with early stage of cervical cancer(FIGO Ⅰ a or Ⅱ a)were studied from Aug.1997 to Sep.2004 in the Affiliated Hospital of Inner Mongolia Medical Collage.Ovarian transposition was performed at the time of radical hysterectomy and pelvic lymphadenectomy in 12 cases who received postoperative radiotherapy;the rest 10 cases did not receive postoperative radiotherapy.Ovarian function was evaluated by serum FSH,LH,E_2 and B-ultrasonography in all of the cases.Results There was a statistically significant difference between the radiotherapy group and the non-radiotherapy group in serum E_2,FSH,LH levels and RI at the 24th month postoperatively.RI had a negative correlation with E_2 and positive correlation with FSH.Conclusion Ovarian transplantation can preserve the endocrine function of ovary for young women with cervical cancer.RI has a negative correlation with E_2 and positive correlation with FSH.RI is the important index of supervising ovarian function.Postoperative radiotherapy can influence RI and ovarian function.

Objective To determine the levels of radiation-induced expressions of HIF-1α and Survivin in three human lymphoma cell lines with or without HIF-1a specific antagonist or HIF-1a siRNA transfection and to explore the possible mechanism of cell radioresistance.Methods Namalwa,Ramos,Raji cells were irradiated with X-rays with or without the combination of echinomycin (EC),a HIF-1α specific inhibitor,or transfection of HIF-1α siRNA.Then the expression levels of HIF-1α and Survivin proteins and mRNAs were determined by Western blot and real-time PCR,respectively.Results After irradiation,the expression level of HIF-1α protein was up-regulated at 10-20 h followed by up-regulation of survivin protein at 24 h (t =7.53-31.31,P ＜ 0.01 ) in three lymphoma cell lines.Radiation-induced up-expression of survivin protein was significantly reduced by either HIF-1α inhibition or EC treatment (t =7.21-32.81,P ＜0.01 ).However,radiation failed to induce up-erpression of survivin at both mRNA and protein levels after transfection with HIF-1α siRNA.Conclusion HIF-1α-Survivin pathway is activated in human lymphoma cells after radiation,which might be involved in the cell radioresistance.

Approaching an advantage in TCM and Chinese herbs, comparing the difference between them in many ways. TCM has macroscopic advantage and microcosmic disadvantage. Point out that only the theory of TCM be respected, the advantages of TCM can be kept.

Animals ; Humans ; Learning ; drug effects ; Memory ; drug effects ; Metals ; toxicity ; Nervous System ; drug effects

Adult ; Female ; Humans ; Phenotype ; Polycystic Ovary Syndrome ; diagnosis ; epidemiology ; ethnology ; genetics

Hematopoietic stem cell transplantation ( HSCT) technology has been widely used to cure some high-risk hematologic diseases and malignancies, with the rapid development of hematology and transplantation immunology, especially human leukocyte antigen matching technology. It might play an important role in biological therapy and gene therapy.

OBJECTIVE To discuss the prevention and countermeasures of occupational bloodborne exposure risks in health care workers.METHODS The data of the exposure materials,and the management measure were collected.RESULTS Totally 397 people were exposed to hematogenous exposure injury,of which 96 doctors people,and 301 nurses,but no one got infection disease.CONCLUSIONS Good management can prevent the injury caused by occupational exposure.

The most advanced semiconductor elements and the control pattern of photoelectric cou- pling in circuit design were adopted and the output of floating earthing was used.Consequently,the perfor- mance of the instrument has been greatly inproved.The output power is adjustable at your desire.The re is a digital display to denote the power and a buzz signal sounds to remind you that the instrument is running normally.Our instrument has the advantages of small in dimensions,light in weight,with stable perfor- mance,safety and high reliability.

Cervical cancer ranks second common cancer in women.More than(490 000) cases are diagnosed worldwide,resulting in 270 thousands more deaths in 2002.The effort to eliminate cervical cancer began over 50 years ago with the introduction of the Pap test.The next significant step in cervical cancer etiology came in the 1980s with the discovery of a link between human papillomaviruses(HPV) and cervical cancer.The success of HPV prophylactic vaccine development is the milestone of cervical cancer prevention of humankind.