1.Application of molecular pharmacognosy in research of Mongolian medicine.
Qianquan LI ; Lishe ZHOU ; Lanping GUO ; Minhui LI ; Na ZHANG ; Qingjun YUAN ; Yuan YUAN
China Journal of Chinese Materia Medica 2011;36(19):2615-2619
Molecular pharmacognosy has developed as a new borderline discipline. Using the method and technology of molecular pharmacognosy, a wide range of challenging problems were resolved, such as the identification of Mongolian medicinal raw materials, etiology of endangerment and protection of endangered Mongolian medicinal plants and animals, biosynthesis and bioregulation of active components in Mongolian medicinal plants, and characteristics and the molecular bases of Dao-di Herbs. So molecular pharmacognosy will provide the new methods and insights for modernization of Mongolian medicine.
Animals
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Drugs, Chinese Herbal
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analysis
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pharmacology
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Humans
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Medicine, Mongolian Traditional
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Mongolia
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Pharmacognosy
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Plants, Medicinal
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chemistry
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classification
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genetics
2.Hemolytic disease of fetus and newborn caused by anti-Di a: a case report
Yuanjun WU ; Yong YANG ; Yanli JI ; Chunyan MO ; Zhongying XIE ; Qianquan YUAN ; Jiajun ZENG ; Miaozhen WEN ; Shujie WU
Chinese Journal of Perinatal Medicine 2020;23(11):778-781
We report a case of a newborn baby who suffered from hemolytic disease of fetus and newborn (HDFN) caused by anti-Di a. The baby presented with worsening jaundice started at three hours after birth and was transferred to Dongguan Maternal and Child Health Care Hospital. The newborn's hemoglobin (Hb) was 82 and 76 g/L at five and nine hours after birth, and the total bilirubin (TBIL) was 243.2 and 309.8 μmol/L, respectively. Blood samples of the newborn and the parents were collected for HDFN immunohematology test twelve hours after birth. They showed that the newborn and the father's blood type was A and RhDCCee, while the mother was A and RhDCcee. Direct antiglobulin test (DAT) indicateda strong positive for the newborn and negative for the parents. The reaction of the reagent to red blood cells for antibody screening with the patient's plasma, red cells eluate, and the mother's plasma were all negative, but were positive with the father's red blood cells. The newborn was recovered after treating with phototherapy, intravenous immunoglobulins and urgent blood exchange (the exchanged blood was the same ABO and RhD blood type and cross-matched). The newborn's plasma and red cells eluate were collected before blood exchange, and the mother's plasma were used to assess the red blood cells reaction, and IgG anti-Di a was identified in each sample. Di a blood typing was positive for the newborn and the father, and negative for the mother. Therefore, the newborn was diagnosed as HDFN caused by anti-Di a.