? As an important part of rehabilitation exercise for patients with chronic obstructive pulmonary disease (COPD), upper limb functional exercise can effectively enhance the capacity of patients with upper limb movement, upper limb function and muscle strength, thus improving the symptoms of upper limb activities and improving the quality of life of patients. This article reviews the methods, intensity, duration, cycle, frequency and outcome evaluation index of upper limb functional exercise for COPD patients, in order to provide basis for choosing appropriate and effective upper limb exercise methods for COPD patients.

Colonoscopy is a gold standard for diagnosis of intestinal pathology. Abundant bowel preparation is the key to colonoscopy. Bowel preparation adherence directly affects the quality of bowel preparation. This paper reviewed the status of bowel preparation adherence of patients with colonoscopy and intervention so as to provide a reference for improving patients' bowel preparation adherence in future.

Exercise is an effective measure to improve expiratory dyspnea and delay lung function decline among the patients with chronic obstructive pulmonary disease(COPD). However, COPD patients have a low level of exercise compliance so far which is the major obstacle to carry out exercise. This paper reviewed the definition, evaluation criteria, research status, influencing factors of exercise compliance so as to provide a scientific reference for improving exercise compliance among COPD patients.

Objective : To explore the application of ZnxNi1－xS@ DOX nanostructures in combined photothermal- chemotherapy treatment of tumors，and to provide new ideas for the study of tumor treatment methods． Methods: The morphology and elementary composition of ZnxNi1－xS nanostructures were characterized by scanning emission e- lectron microscopy and other methods．The photothermal properties of ZnxNi1－xS nanostructures were explored by infrared thermal camera．The release of DOX under different temperature and pH was investigated by fluorescence spectrophotometer．The biosafety of ZnxNi1－xS nanostructures and the in vitro antitumor properties of ZnxNi1－xS@ DOX nanostructures were investigated by MTT assay. Results : The as-prepared ZnxNi1－xS nanostructure had good dispersion and uniform size．The ZnxNi1－xS nanostructures had good photothermal effect．The drug release behavior showed temperature and pH responsiveness．The MTT assay showed that ZnxNi1－xS nanostructures were nontoxic to normal cells．ZnxNi1－xS@ DOX nanostructures could significantly inhibit the growth of tumor cells under near-infra- red illumination． Conclusion The as-prepared ZnxNi1－xS nanostructure has good biocompatibility，on the basis of which the ZnxNi1－xS@ DOX nanostructures achieve good antitumor performance，which can be used for combined photothermal-chemotherapy treatment of tumors.