Objective:To understand the psychological experiences of adolescents with comorbid depression and anxiety disorders who have completed Williams life skills training (WLST) .Methods:This is a qualitative study. A total of 16 adolescents with comorbid depression and anxiety disorders who were treated at Hangzhou Seventh People's Hospital between March 2021 and January 2022 and completed the WLST during their hospitalization were selected by purposive sampling. Semi-structured interviews were conducted to gather and subsequently analyze interview data, leading to the extraction of main themes.Results:The psychological experiences of adolescents with comorbid depression and anxiety disorders after completing WLST included correctly recognizing and effectively addressing social phobia, strengthening psychological adjustment capabilities and enhancing self-efficacy, discovering a sense of belonging within a group.Conclusions:WLST can change depression and anxiety conditions, alleviate the fear of social interactions, enhance self-regulation efficacy, provide a sense of belonging within a team, maintain good mental and physical health, and improve the quality of life in adolescents with comorbid depression and anxiety disorders.