Objective To standardize the modeling and evaluation of type 2 diabetic gastric mucosal injury rat model of spleen deficiency. Methods Male SD rats were randomly divided into normal group and model group, type 2 diabetic rat model with gastric mucosal injury was established by the injection of small-dose streptozotocin (STZ) combined with feeding of high fat and sugar forage and gastric gavage of 30% ethanol solution. After the modeling, we examined the levels of fasting blood glucose ( FBG) , fasting insulin ( FINS) , superoxide dismutase (SOD), malondialdehyde (MDA) and nitric oxide (NO) in the rat serum, and gastric and pancreatic tissue pathology was evaluated after HE staining. Modern medical evaluation method was used for the statistics of information collected by four diagnostic methods of traditional Chinese medicine ( TCM) , and for the identification of properties and evolution of TCM syndromes. Results Type 2 diabetic gastric mucosal injury rat model had been established in 75% of the rats. And 10-16 weeks after the modeling, the model rats had the syndrome of spleen deficiency, showing as persistent emaciation, decreased grasping force, weak activities in open field test, pale tongue nature, decreased r value of the claw and tail, increased defecation frequency, softening of loose stool. Of all the model rats, 78% had the features of diabetes, one indicator of qi deficiency syndrome, and one or more specialized spleen-related indicators. Conclusion These results suggest that type 2 diabetic gastric mucosal injury rat model can be successfully induced by the injection of small -dose streptozotocin ( STZ) combined with feeding of high fat and sugar forage and gastric gavage of 30% ethanol solution, and the time window of spleen deficiency for type 2 diabetic gastric mucosal injury rat model is 10-16 weeks after the modeling.

Objective To provide reference basis for HIV and syphilis prevention and control work by surveying the in-fectious status of HIV and syphilis of the Cangnan County migrant workers. Methods An anonymous questionnaire survey was conducted on the migrant workers over the age of 18 , and their serum samples were collected , and tested for syphilis and HIV antibody. Results One case with positive HIV antibody was detected , and the infection rate of syphilis was 1.38%;Syphilis infection rates in different sectors of migrant workers had significant difference (χ2=7.06, P<0.05);The cognitions of the transmitted way on HIV and syphilis in different sectors of migrant workers had significant differences (χ2=125.10,P<0.01). Conclusion The risk of HIV and syphilis infection exists in Cangnan County migrant workers, prevention work and health education should be worthy of attention.