The compositions and contents of fatty acids in the meat and viscera in Chlamys ferreri near Yantai seacoast, Shandong Province were studied in detail. The result showed that the contents of the unsaturated fatty acids in the meat and wastes were 65. 0% and 66. 2%, respectively. Moreover, the contents of the polyunsaturated fatty acids and EPA+DHA were 55. 1% and 37. 5% in the meat, respectively. The contents in the viscera were 48. 8% and 22. 2%, respectively.

Many controversies and unanswered questions surround AIS(adolescent idiopathic scoliosis),the most difficult one is the absence of information about its aetiopathogenesis.Although bracing has been regarded as the standard of care for patients at a high risk of progression,it has never been subjected to rigorous assessment of either its efficacy or effectiveness.With respect to surgical management,although technology has greatly increased the safety with which we can correct spinal deformity and preserve spinal balance,long-term results of these changing methods of management are absent.Surgery can reduce deformity and prevent further progression;thereby decreasing the risk of future cardiopulmonary compromise,but its role in the prevention of other negative long-term effects of scoliosis is not clear.In this paper we discuss present notions about aetiopathogenesis,natural history,non-operative treatment,and surgery.

Objective To observe the effects of repetitive transcranial magnetic stimulation (rTMS) on cognitive function in rats with chronic cerebral hypoperfusion.Methods The animal model of chronic cerebral hypoperfusion was established in 30 Sprague-Dawley rats by surgically induced bilateral common caroid artery stenosis,who were then divided into a control group and a treatment group.The rats in the treatment group were administered with 20 Hz rTMS 4 weeks postoperation for 7days.Another 10 rat subject to sham operation served as blank controls.The cognitive function was assessed by Morris water maze (MWM) at the time points of 2nd,3rd,4th and 5th days after ending of the 4 weeks of tretment.The morphologic changes of hippocampus neurons were observed with HE staining.The apoptosis was examined by TUNEL,the expression of Bcl-2 or Bax protein was determined using immnunohistochemistry assay.Results At all the time points the MWM escape latency in the rTMS group was shorter than that in the control group (P ＜ 0.01).The percentage of crossing the corresponding platform during the same time period in platform quadrant in the rTMS group was significant higher than that in the control group (P ＜ 0.01).Compared with the control group,the treatment group demonstrated significantly decreased percentage of neuronal apoptosis (P ＜0.05),as well as increased expression of Bcl-2 protein (P ＜0.01) and reduced expression of Bax protein (P ＜ 0.01).Conclusion rTMS can improve the cognitive dysfunction in rats caused by chronic cerebral hypoperfusion,probably through inhibiting neuronal apoptosis in hippocampus region.

Objective:The present study discussed the clinical diagnosis and treatment of pancreatic body and tail carcinoma. Methods:The data of 52 patients with pancreatic body and tail carcinoma treated in Tianjin Medical University Cancer Institute and Hospital from January 2008 to December 2012 were reviewed retrospectively. The data included historical materials of perioperative examination and therapy. The data of 49 cases were reviewed retrospectively, and the median survival was calculated by the Kaplan-Meier method. The effects of the clinicopathologic parameters on the prognosis of patients with pancreatic body and tail carcinoma were examined by the log rank test. Results:Thirty-eight patients underwent exploratory surgery among which 24 had surgical resection, and the standard procedure was distal pancreatectomy plus splenectomy. The tumor staging was stage I in five patients (13.16%), stage II in nineteen patients (50%), stage III in five patients (13.16%), and stage IV in nine patients (23.67%). The median survival time was 18.0 ± 1.23 months for patients who received radical resection and 10.0 ± 2.71 months for patients who underwent nonspecific treatment or palliative therapy. The radical resection was associated with a longer survival period than the nonspecific treatment or palliative therapy (P<0.01). Conclusion:Early diagnosis is the key to achieving long-term survival. The radical resection plays an important role in improving the surgical treatment.

Neurofeedback as a behavior therapy measurement for ADHD has gained increasing attention in recent years.Based on researches have been published of neurofeedback in ADHD in nearly 5 years,the researches development of neurofeedback are reviewed.The data showed that TBR,SMR and SCP neurofeedback are clinically effective treatment for ADHD.Future controlled clinical trials should focus on such known protocols for specific research,and be designed in line with learning theory.

Objective:To assess the analgesic effects and side effects of buprenorphine sublingual tablet in dental treatment.Methods:500 cases for dental treatment were selected.Before management of teeth,all the patients took 0.2 mg of buprenorphine sublingual tablet.The VAS score,Kuttner face score and side effects after dental treatment were recorded.Results:The VAS scores of the patients underwent preventive,operative and prosthetic treatments were 3.99?2.34,2.72?1.67 and 2.78?1.55,the Kuttner scores of those 1.98?1.23,2.66?1.04 and 2.03?0.93,respectively.Side effect was not observed in all the patients.Conclusion:Buprenorphine sublingual tablet can relieve the pain in dental treatment.

Bladder pain syndrome (BPS) is a chronic disease characterized by urinary symptoms and pain in or around the bladder with uncertain reasons. The incidence of BPS is higher in the female and people in American and Europen countries. The BPS patients' quality of life has been damaged and a new disabled group has been formed. The pathogeneses of BPS include pathogens inducing inflammation, chronic ischemia and ischemia-reperfusion injury producing degeneration in bladder, lower urinary epithelium dysfunction, apoptosis in bladder tissue, epigenetic reprogramming, abnormal intracellular signaling pathway, pain regulating dysfunctioning, and autophagy inhibit-ed. There is no identified diagnosis for BPS. Cystoscopy, urodynamia, and biomarks in blood or urine are helpful in diagnosis. Diet, psycho-logical intervention, oral medicine, intravesical therapy, nerve blocking and nerve stimulation, and surgeries have been used for it, but the ef-ficacy remains unsatisfied.

Objective To discuss the relationships between expression levels of CD147 and vascular endothelial growth factor C (VEGF-C) in lung squamous cell carcinoma and adenocarcinoma and the clinicopathological features.Methods The expression of CD147 and VEGF-C in 57 lung cancer tissues was detected by immunohistochemical method.Results The positive expression rates of CD147 and VEGF-C in 57 lung cancer tissues were 63.16 ％ (36/57),66.67 ％ (38/57) respectively.The expression of CD147 and VEGF-C in lung squamous cell carcinoma and adenocarcinoma had no statistical difference (both P ＞ 0.05).The expression of CD147 and VEGF-C in lung squarnous cell carcinoma and adenocarcinoma had relationship with lymph node metastasis and tumor TNM stage (all P ＜ 0.05),however they had not correlation with the patient' s age,sex,smoking and tumor cell differentiation extent irrelevant (all P ＞ 0.05).The expression of CD147 was related positively with VEGF-C (P ＜ 0.01).Conclusions CD147 and VEGF-C play important roles in the progression and metastasis of lung squamous cell carcinoma and adenocarcinoma,which may have a synergistic effect.The joint detection of CD147 and VEGF-C can be used as a useful prognostic indicator in patients with lung cancer.

Zebrafish has been widely used as an important model system in research fields of genetic and develop -mental biology over the past 20 years.Similar to the mammalians and other vertebrate animals , zebrafish also has various tissue barriers.In recent years, more and more important progress of tissue barrier studies have been achieved using ze -brafish as in vivo model, such as blood-brain barrier.These findings contribute to the understanding of the mechanisms of diseases caused by the disorders of physiological barriers .It also helps with the modulation of the permeability of tissue bar-riers for drug delivery .This review summaries recent progress of zebrafish applications in the study of tissue barriers , such as blood-brain barrier, blood-retina barrier, epidermal barrier, etc.

BACKGROUND:Evaluation of the newly formed bone at the distraction site by the imaging technologies is the cornerstone for terminating the limb lengthening successfuly.In the early stages of the distraction, the X-ray cannot detect any evidence of new bone formation within the distraction sites, whereas ultrasound can acquire wealth information about new bone and surrounding soft tissues. OBJECTIVE: To explore the application value of Doppler ultrasound in the evaluation of limb lengthening in order to promote its clinical application. METHODS: A computer-based search was performed on the CNKI database and PubMed database for articles related to ultrasound in the evaluation of limb lengthening published from January 1989to October 2014. The keywords of distraction osteogenesis, ultrasonography, external fixation, fracture healing in English and Chinese were used to search the articles by title and abstract. Finaly, a total of 24 articles were included to review. RESULTS AND CONCLUSION: Ultrasound is an effective method to evaluate the limb lengthening in early stage. It can not only detect the formation and maturation of the new calus, but also can evaluate the forming speed and the quality of the new cals. Moreover, ultrasound can be used to evaluate the situation of the soft tissue near the distraction site. Complications associated with the limb lengthening can be observed timely by the ultrasound. Ultrasound is of great significance in the evaluation of distraction osteogenesis.