Objective To discuss the influence of Ginkgo biloba extract on platelet aggregation of the patients with acute cerebral infarction.Methods 102 patients with acute cerebral infarction were selected and randomly divided into the control group and the observation group,each group had 51cases.The patients of the control group were given the conventional drug therapy,while the observation group were given the Ginkgo biloba extract treatment on the basis of the treatment of the control group.Results The platelet aggregation of the two groups after treatment made significant difference compared with that before treatment(P ＜ 0.05).The platelet aggregation caused by ADP was (65.1 ± 8.1) ％ and was obviously lower than that of the control group (t =5.732,P ＜ 0.05).The platelet aggregation caused by AA was (30.1 ± 5.2) ％ and was obviously lower than that of the control group (t =6.897,P ＜0.05).The platelet aggregation caused by PAF was (42.1 ± 6.3) ％ and was obviously lower than that of the control group (t =6.013,P ＜ 0.05).The neurological function of the two groups after treatment made significant difference compared with that before treatment (P ＜ 0.05).The socres of the observation groupafter treatment was (5.98 ±1.09),which was obviously lower than that of the control group (t =5.469,P ＜ 0.05).Conclusion Ginkgo biloba extract could significantly reduce the platelet aggregation of the patients with acute cerebral infarction and deserved promotion.

Objective To study the effects of β-aescine sodium plus oxiracetam on plasma homocysteine (Hcy) and monocyte chemotactic factor(MCP-1) protein in patients with acute cerebral infarction.Methods 117 patients with acute cerebral infarction were randomly divided into the two groups,the observation group (n =60 cases) and the control group (n =57 cases).The patients in the control group were treated with the conventional treatment,while the patients in the observation group were treated with joint treatment ofβ-aescine sodium plus oxiracetam.They were treated for 14 days.Plasma Hcy and MCP-1 were detected.Results The total efficicies were 95.0％ in the observation group and 84.5％ in the control group.There was a significant difference between two groups (x2 =5.801,P ＜0.05).Plasma Hcy and MCP-1 were decreased after treatment (t =9.551,4.296,2.001,21.070,P ＜ 0.05,P ＜0.01).Plasma Hcy and MCP-1 in the observation group were lower than these in the control group (t =4.997,25.276,all P ＜ 0.05).Conclusion β-aescine sodium plus oxiracetam can decrease plasma Hcy and MCP-1 in patients with acute cerebral infarction.

Against the widely and popular cognition in TCM circle which lumped together“blood”in TCM with blood of western medicine,the polyphyly and multiplayer natures of the essence of conception of“blood”in TCM are discussed.And the conception “blood picture”of blood in TCM is put forward based on the invented characteristics of establishment of TCM theories and with reference to point of view of relevant adaptation of the human body to national environment in the viscera state theory.

[Objective]To explore the clinical outcome and advantages of surgical treatment of thoracolumbar fracture without neurological defect.[Method]From July 2003 to July 2006,23 cases of AO type A or type B thoracolumbar fracture without neurological defect were treated operatively. The anterior height of vertebral body lost more than 40% before operation,and 70% of the patients had an intracanal fragment.Transpedicular screw reduction and fixation were performed and bone fusion with inter transverse process and interlaminar bone graft were performed.[Result]The anterior height of vertebral body and the intervertebral body angle improved significantly after operation. And the rate of spinal stenosis decreased from 38% before operation to 12% 3 months after operation. 81% achieved bone fusion 1 year after operation.[Conclusion]The surgical treatment of thoracolumbar fracture without neurological deficit has the advantages of restoration of vertebral body height effectively,correction the deformity,restoration of the spinal volume and prevention the progressive of neurological deficit.In order to achieve long-term stability,bone fusion should be performed at the some time.

Objective:To discuss the application of lean management of medical consumables in stomatological hospital and evaluate the operation effect.Methods: Based on the lean management of medical consumables of School of Stomatology, China Medical University, the medical consumables are composed of high valuable and common consumables. Traceable and sub-base management are carried out for all the medical consumables.Results: Lean management runs well and improves the scientificity and precision of hospital management.Conclusion: The operation costs are reduced and management benefit is increased.

Objective To compare the effectiveness and safety of endoscopic polycyclic mucosal resection(EMBM)and endo-scopic submucosal dissection(ESD)in the treatment of esophageal intraepithelial neoplasia.Methods 85 cases of esophageal intra-epithelial neoplasia patients,including 45 cases treated by EMBM and 40 cases treated by ESD.To compare the efficacy,complica-tions,operation time,and medical fees of the two treatment methods by analysis of relevant clinical data.Results Once resection rate of the EMBM treatment group was 97.8%(44/45),and 95.0%(38/40)for the ESD treatment group,there is no significant difference between the two groups(P>0.05);Endoscopy of both treated patients in the postoperative 1,3,6,and 12 months showed no recurrence;The complications incidence of bleeding and perforation of the EMBM treated group(8.89%,0)was significantly lower than that of the ESD treated group(35.00%,15.00%),P<0.05;The average operation time of the EMBM treated group [(26.5±14.2)min]was significantly lower than that of the ESD treated group[(65.2±26.1)min],P<0.05;The total cost of hospitalization of the ESD treated group(18 000 yuan)was significantly higher than the EMBM treated group(8 500 yuan),P<0.05.Conclusion Compared with ESD,EMBM has an easier operation,less complications and patient consuming,and it is suitable for application in primary hospitals.

Toll-like receptor( TLR )is a newly discovered important innate immune receptor and signal transduction transmembrane receptor.By the TLR in the surface of immune cells,body can recognize conserved pathogen-associated molecular patterns,to stimulate the production of cytokine,increased costimulatory molecule expression of antigen-presenting cell,activating T cells,establishing a closely-linked bridge between the innate immunity and acquired immunity.TLR9 is a member of Toll-like receptor family,mainly identify viral or bacterial DNA containing unmethylated CpG dinucleotides.Studies have showed that TLR9 is in the immune system's recognition of EB virus,and it plays an important role in the infection and transformation of the EB virus.This paper reviews the studies of the interaction of TLR9 with EB virus.

Aged ; Angiofibroma ; metabolism ; pathology ; Desmin ; metabolism ; Diagnosis, Differential ; Female ; Humans ; Inflammation ; Leiomyosarcoma ; pathology ; Neoplasms, Muscle Tissue ; metabolism ; pathology ; Vimentin ; metabolism ; Vulvar Neoplasms ; metabolism ; pathology

Objective To study the genetic diversity of ITS sequences of Radix et Rhizoma Salviae Miltiorrhizae (RRSM) and plants of Salvia L. and analyze the utility of ITS sequences in molecular authentication of RRSM and phylogenetic of plants of Salvia L. Methods The ITS gene fragment was amplified using a pair of primers. The PCR products were purified and sequenced by the methods of Sanger dideoxy. Results The DNA sequence of 222-224 bp ITS1, 220-223 bp ITS2 gene fragments and 5.8S rDNA were obtained from 13 samples of Salvia L. The interspecific substitution varied from 0% to 12.16% at ITS1 and 0.5% to 13.51% at ITS2. The intraspecific substitution of RRSM is 0% to 0.9% at ITS1 and 0% to 0.5% at ITS2. The substitution between group of Salvia L. and outgroup varied from 16.07% to 20.27% at ITS1 and 15.91% to 20.27% at ITS2. The phylogenetic tree based on ITS1 and ITS2 data was set up. Conclusion The ITS1 and ITS2 gene fragments are highly conservative at intraspecific level in RRSM, while they are less conservative at interspecific level in Salvia L. They are least conservative between group of Salvia L. and outgroup. Hence, the sequence of this fragment is a good molecular marker for authentication of RRSM and can be used for further study on the phylogenesis for plants of Salvia L.