Objective To explore the cause of anastomotie fistula after esophagus cancer and cardiac cancer operation and its prevention and treatment.Methods After excising the tumors,the esophagogastrostomy was performed in 60 cases,in which the cervical anastomose in 48 cases and intrathoracic anastomose was adopted in 12 cases.We retrospectively analyzed its prevention and treatment. Results Caevial anastomose in 48 cases,4 patients with anastomotic fistula in the died,while none of 12 cases in the cervical anastomose died. Conclusions Careful procedure and improving the anastomotic methods are the key factors to reduse the anastomotic fistula,the accurate control of infection and full nutritive support are the effective methods to decrease the mortality rate of this disease.

Objective 　To evaluate curative effect of Quhuang Tieji on hypercholesterolemia of newborn. Method　120 newborn with hypercholesterolemia were randomly divided into treatment group and control group,two group all accepted routine treatment,but the former group was treated with Quhuang Tieji at the same time.NANA and BAER were measured before and after treatment in two group.Results 　The scores of NBNA,latency of V wave,Ⅲ-V wave internal were significantly different between treatment group and control group after treatment.Conclusion　Quhuang Tieji can improve the scores of NBNA and latency of BAER , it had well curative effect to hyperbilirubinemia of newborn.

BACKGROUND:Previous studies with regard to male track short-distance cyclists are concentrated on the descriptive and comparison studies of morphological characteristics of athletes Up to now,few studies report the relationships between morphological characteristics and sports performance in men 1-km cyclists.OBJECTIVE:To explore an effective morphological index for evaluating physical stamina level of men cyclists in 1-km time trials,and to establish morphological models and evaluation standards for men cyclists in 1-km time trials in China.METHODS:Totally 17 men who had prepared for the 1-km cycling time trials of the fifth cycling city sport meeting in Taiyuan were examined.With the methods of step by step regression,gray correlation,measurement and evaluation theory,the morphological characteristics of these excellent cyclists were explored,and utilized in establishing morphological models,single-grading table and the ranking evaluation criteria.RESULTS AND CONCLUSION:The typical indexes of excellent 1-km men cyclists were body height and fat-free body weight.The morphological characteristics of these excellent cyclists were as follow:tall,long leg and Achilles tendon;high foot arch;heavy body weight and fat-free body weight;as well as thick thigh The present study established the evaluation model of the morphological characteristics and evaluation standards for 1-km men cyclists

Gangliosides are sialic acid-containing glycosphingolipids and abundant in the brain. Some studies showed that glycosphingolipids not only could improve the differentiation of neurons, neurite outgrowth and synaptogenesis, but also could modulate neuronal plasticity and improve neurological function after cerebral damage. GM1 was so far most widely studied glycosphingolipids. It is believed that the regulatory functions for calcium homeostasis and the interaction between GM1 and neurotrophins are essential in the mechanisms underlying its neuroprotection. In addition, GM1 has also anti-excitotoxicity, anti-oxidation and vasodilation properties. Various forms of chronic neurodegenerative diseases and hypoxia/ischemic encepha-lopathy are characterized by progressive loss and apoptosis of neurons, the neuroprotective and neruotrophic effects of GM1 could play pivotal role in the treatment of these diseases. Nowadays, GM1 was widely used for the treatment of Parkinson's disease, stroke, hypoxia-ischemic encephalopathy, craniocerebral trauma, spinal cord injury and peripheral neuropathy. Further researches for the mechanisms of GM1 will provide new strategies for the treatment of central nervous system diseases.

Objective To discuss the application of improved agarose electrophoresis for detecting bone alkaline phosphatase(BALP) isoenzymes in the diagnosis of metastasis in prostate carcinoma(PCa).Methods Serum ALP isoenzymes in 50 persons undergoing physical examination and 163 cases of PCa were detected by the improved agarose electrophoresis after treating serum by neuraminidase.Results (1)The resolution of liver and bone ALP by the common agarose gel electrophoresis was lower,and which was increased by the modified agarose electrophoresis.(2)Total ALP and BALP in the PCa group were higher than those in the control group;total ALP and BALP activity in the PCa bone metastasis group were higher than those in the control group and non-metastasis group(P<0.05),there were no statistical difference in BALP and total ALP between the non-bone metastasis group and control group(P>0.05).BALP and total ALP in bone metastasis of prostate carcinoma were higher than no bone metastasis.Conclusion Bone ALP has a certain correlation with PCa bone metastasis,also between bone ALP and bone metastasis of carcinoma.After treating serum by neuraminidase,adopting the improved agarose gel electrophoresis for separating ALP isozymes contributes to the clinical auxiliary diagnosis of PCa bone metastasis.

BACKGROUND:The incidence of posterior cruciate ligament injury combined with other knee ligament injuries is relatively high, but studies on the internal dynamic stress change of these ligaments are stil rare. OBJECTIVE:To simulate three-dimensional finite element model of the normal human knee and the complete posterior cruciate ligament rupture (III injury), calculate and analyze the stress distribution and changes of the medial collateral ligament, the lateral collateral ligament and the anterior cruciate ligament in the normal knee model and the complete posterior cruciate ligament rupture model. METHODS:We collected CT and MRI images of the healthy male right knee, and established three-dimensional finite element model of the normal human knee by using E-feature Biomedical Modeler, and ANSYS software. The simulation of a flexion moment at 0°, 30°, 60°, varus/valgus and internal/external rotation torque was applied on the established three-dimensional finite element model of the normal knee. The stress of posterior cruciate ligament, lateral collateral ligament, anterior cruciate ligament and medial col ateral ligament was analyzed. During simulation of complete posterior cruciate ligament rupture, the stress of lateral coll ateral ligament, anterior cruciate ligament and medial col ateral ligament was analyzed. RESULTS AND CONCLUSION:Three-dimensional finite element biomechanical analysis data revealed that after posterior cruciate ligament rupture, the stress of lateral coll ateral ligament during inversion and external rotation of the knee joint obviously increased, but the stress of anterior cruciate ligament and medial collateral ligament slightly altered. These findings suggested that posterior cruciate ligament rupture may cause secondary injury to other ligaments of the knee joint, and further support the importance of the dynamic stability of the knee joint.

Hp phenotypes were determined by polyacrylamide disc-electrophoresis in sera from 555 individuals of Han population in Kunming. HP phenotype frequencies were simillar to that of Shanghia, Quandong Han Population and the other six phenotypes (1-p,2-1F, F K etc) could be detected in Kuming population by the same method.

[Objective]To explore the clinical outcome and advantages of surgical treatment of thoracolumbar fracture without neurological defect.[Method]From July 2003 to July 2006,23 cases of AO type A or type B thoracolumbar fracture without neurological defect were treated operatively. The anterior height of vertebral body lost more than 40% before operation,and 70% of the patients had an intracanal fragment.Transpedicular screw reduction and fixation were performed and bone fusion with inter transverse process and interlaminar bone graft were performed.[Result]The anterior height of vertebral body and the intervertebral body angle improved significantly after operation. And the rate of spinal stenosis decreased from 38% before operation to 12% 3 months after operation. 81% achieved bone fusion 1 year after operation.[Conclusion]The surgical treatment of thoracolumbar fracture without neurological deficit has the advantages of restoration of vertebral body height effectively,correction the deformity,restoration of the spinal volume and prevention the progressive of neurological deficit.In order to achieve long-term stability,bone fusion should be performed at the some time.

Objective To investigate the effects of mesalazine combined with Xianglian pills on cytokines and immunocytes in ulcerative colitis. Methods A total of 86 patients with ulcerative colitis from our hospital were collected and randomly divided into experimental group and control group with 43 cases in each group.Patients in the control group were treated by mesalazine, patients in the experimental group were treated by mesalazine combined with Xianglian pills treatment.The cytokines and immunocytes levels and efficacy between two groups were compared.Results After treatment, the clinical effective rate of the control group 69.77% was lower than the experimental group 88.37%, with statistical significance ( P <0.05 );compared with the control group, the TNF-αlevel of the experimental group was lower than the control group, IL-2, IL-4 and IL-10 levels were higher than the control group;the serum TFF1 and TFF3 levels were higher than the control group;CD3 +, CD4 +/CD8 +and NK cells levels were higher than the control group, the level of CD8 +was lower than the control group, with statistical significance ( P<0.05 ) .Conclusion Mesalazine combined with Xianglian pills in the treatment of patients with ulcerative colitis could reduce the inflammatory reactions and improve the clinical efficacy, with lower adverse reactions.

Due to historical reasons, public medical institutions are legion in medical resources-intensive big and medium-sized cities. With the deepening of reform in urban medical and health systems and social undertakings and the transformation of government functions in public health management, the disadvantages of having an excessive number of public medical institutions have become increasingly evident, for it can lead to heavy financial burdens for the government and insufficient medical market competition and vitality. The paper discusses reform in the property right system of public medical institutions in resources-intensive cities from three aspeets, viz. the necessity of reform the major problems to be dealt with, and the basic framework of the reform. It also gives a detailed account of the position and role of the government in this reform.