3.Clinical distribution and drug resistance analysis of stenotrophomonas maltophilia
Chinese Journal of Primary Medicine and Pharmacy 2015;(15):2356-2357
Objective To investigate the clinical distribution and drug resistance of stenotrophomonas maltophilia and to provide reference for the clinical application of drugs and to control the nosocomial infection. Methods MicroScan autoSCAN4 and Kirby -Bauer (K -B)method were used to assess the bacteria and test the drug sensitivity.The data were analyzed with software WHONET5.6.Results The isolation rate was the highest in respiratory specimens.There was a highest isolation rate of 90.2%.Drug sensitive test showed that stenotrophomonas maltophilia was most sensitive to minocyline,and the resistance rate was 3.6%.The resistance rates of trimethoprim -sulfamethoxazole,levofloxacin and cefoperazone -sulbactam were12.2%,13.4% and 26.8%.Conclusion Drug resistance monitoring of stenotrophomonas maltophilia should be enhanced.Treatment based on drug susceptibility test should be adapted as soon as possible.
4.Thymoma with pure red cell aplasia
Journal of Chongqing Medical University 2003;0(05):-
Objective:To explore the diagnosis and treatment of thymoma with pure red cell aplasia(PRCA).Methods: From May 1999 to March 2006,the cases of thymoma with PRCA were treated.The clinical data was analysed and the Chinese literature was reviewed.Results:The cases of thymoma with PRCA accounted for 4.2%(3/70)of total thymoma treated in the same period,2 cases underwent thymomectomy.No recurrences of thymoma or PRCA was found in 1 case 3 years and 1 case 6 months after operation.There was no effect on 1 case undergoing surgical exploration only.Conclusion: Thymoectomy is the first choice for thymoma with PRCA.The long term effects should be further followed up.
5.Experimental study of inhibited cardiomyocyte apoptosis and improved cardiac function by simvastatin after myocardial infarction
Journal of Chongqing Medical University 1986;0(04):-
Objective:To investigate the effect of simvastatin on cardiomyocyte apoptosis and cardiac dysfuction after myocardial infarction.Method:Simvastatin was administrated to the rats with myocardial infarction which was modeled by left anterior descending coronary artery ligation. After 7days, the apoptotic myocyte cells were quantified by TUNEL staining;left ventricular function index was measured by echocardiography and the level of serum lipid was measured by biochemical method.Results:Compared with infarction group, apoptotic myocyte cells in simvastatin group significantly decreased in infarction zone,border zone and non-infarction zone(P0.05).Conclusion:Simvastatin inhibits cardiomyocyte apoptosis and improves cardiac function after myocardial infarction.
6.Effect of smoking on semen quality,serum testosterone and level of L-carnitine in seminal plasma
Journal of Chongqing Medical University 2003;0(06):-
Objective:To study the effect of smoking on the semen quality,the level of serum testosterone and L-carnitine in seminal plasma.Methods:90 men,who had the history of pregnancy individual,were divided into three groups.Semen parameters(volume,sperm density,viability,motility),serum testosterone and L-carnitine were examined.Results:There are significant difference between A and C group about sperm density and the percentage of progressive motile spermatozoa,and between B and C group about motility,and between A and C about serum testosterone,and between A and B about the level of L-carnitine,especilly between A and C group(P
7.Clinical analysis of 86 patients with acute disseminated encephalomyelitis
Journal of Chongqing Medical University 2007;0(08):-
Objective:To elucidate the clinical features of acute disseminated encephalomyelitis,as well as its diagnosis and treatment.Methods:The general clinical manifestations,lesion locations,the results of cardinal ancillary investigations,and treatment as well as prognosis of 86 ADEM patients were comprehensively analyzed.Results:ADEM mainly occurred in children,young and middle-aged people.Their onsets were relatively acute.The upper respiratory tract infection and vaccination,measles,german measles,chickenpox,mumps,scarlet fever were the main predisposing factors.The immunoglobin in CSF increased.Spinal cord,cerebellum,cerebral medullary substance and brain stem were often involved.Imaging investigations,electrophysiology and immunology were helpful for diagnosis.The administration of glucocorticoid was effective.Conclusion:In addition to clinical features,neuroelectrophysiology,CSF immunology and imaging investigations altogether greatly aid clinical definite diagnosis.It is important to treat the patients in time and properly for the better prognosis.
8.Closure of atrial septal defect with occluder by minimally invasive operation
Journal of Chongqing Medical University 2007;0(10):-
Objective:To Summarize the experience of atrail septal defecf (ASD) closure with occluder by minimally invasive operation. Methods:Six patients with ASD were treated by microcnvasive method to close ASD with special occluder device. The age of patients was 27 to 57 years. The diameter of ASD was 22 to 40mm. All patients were anaesthetized and a 2-3cm long incision was made in the 4th intercostal space of right side of sternum. All the cases were treated with special occluder device under the echocardiography guidance. Results:ASDs of 5 cases were successfully occluded. No Complications happened. They were discharged from the hospital 3 to 5 days after the operation. After 3 to 15 months tracing,no risidual shunt was found,heart size and function were improved. Conelusion:The minimally invasive operation to close ASD with special occluder device is safe and efficient. The Long-term follow-up remains to be studied. [
9.Current status and coming future of pediatic interventional radiology in China
Journal of Interventional Radiology 2006;0(11):-
As an important branch of interventional radiology and pediatric radiology, pediatric interventional radiology has been widely accepted by both clinicians and patients' parents due to its marked efficacy and less invasiveness, but its prevalence is still yet to be recommended. This paper overviews the current status of pedatric interventional radiology in our country, its specificity during the clinical management, and existing problems to be solved.
10.Detection and Identification of Tilletia controversa K?hn by Real-time fluorescent PCR
Microbiology 1992;0(06):-
By analysing the ribosome gene(rDNA) sequences in externally transcribed spacer(ETS) of wheat T.controversa(TCK) and its similar spacies T.caries(TCT)and T.foetida(TFL).The special sequences of TCK's ETS have been found,.And designed Taqman probe according to the special sequences,TCK has been successfully detected by using Real-time Fluorescent PCR.