1.Indications and related problems of phototherapy intervention for neonatal iaundice
International Journal of Pediatrics 2012;39(1):26-29
Neonatal jaundice or hyperbilirubinemia is a common occurrence in newborns.Most cases of neonatal jaundice have a benign course.Hyperbilirubinemia can be best understood as a balance between the production and elimination of bilirubin,with a multitude of factors and conditions affecting each of these processes.When an imbalance results because of an increase in circulating bilirubin ( or the bilirubin load)to significantly high levels( severe hyperbilirubinemia),it may cause permanent neurologic sequelae( kernicterus),which is preventable if the hyperbilirubinemia is identified early and treated appropriately.Phototherapy for jaundice is a common treatment in neonatal medicine and is used to prevent the neurotoxic effects of bilirubin.Phototherapy for hyperbilirubinemia should be based primarily on total serum bilirubin levels of the infant's age in hours and other factors that affect the risk of bilirubin encephalopathy.
2.Discussions on delivery mode of medical consortia within the ongoing health reform
Chinese Journal of Hospital Administration 2013;(5):321-324
A review of the development milestones of medical consortia during the 20th century in China,probed into the practice and strategy of medical consortia delivery modes.Such modes are designed to build an integrated regional medical service resources and functions,create the delivery service chain to cater to primary medical service demands in urban and rural areas,and meet China's present conditions.Author of the paper proposed better supporting policies and measures based on improving the basic strategy of the medical consortium's delivery mode.
3.Observation on postoperative analgesia effect of sacral canal injection of dezocine before procedure for prolapse and hemorrhoids operation
Chinese Journal of Primary Medicine and Pharmacy 2011;18(11):1458-1459
Objective To observe postoperative analgesia effect of sacral canal injection of dezocine before procedure for prolapse and hemorrhoids operation.Methods A total of 160 patients with mixed hemorrhoid were divided into two groups:observation group(n=80)and control group(n=80).Dezocine 5 mg was injected in sacral canal before operation in observation group and same dose of saline was injected in control group.The postoperative analgesia effect,complication and general condition of patients were observed.Results Compared with the control group,significandy more slightless in pain were found in observation group.There was no effect on the wound healing time of patients.The rate of complication in observation group was lower.Conclusion The sacral canal injection of dezocine was a safe,simple and effective analgesic method.
4.Diagnostic value of MDCT in parotid gland basal cell adenoma
Chinese Journal of Primary Medicine and Pharmacy 2011;18(8):1036-1038
Objective To investigate MSCT findings of CT features of basal cell adenomas in the parotid gland, and improve its diagnostic value.Methods 12 cases plain and enhanced CT findings of basal cell adenomas in the parotid gland were retrospectively analyzed for their position, numbers, size, shape, edge, density and enhancement features,which were all verified pathologically after surgery.Results (1) There were 4 males and 8 females, of which 7 females were in the age of 50 ~59; (2) There were 14 lesions in 12 cases,11 cases were single and 1 case was unilateral multiple ( 3 lesions) ; (3) 12 lesions were situated in superficial lobe of the parotid gland, and 2 lesions were situated between superficial lobe and deep lobe of the parotid gland; (4) The maximum diameter of all lesions were <3cm,of which 5 lesions were < 1em,and 6 lesions were 1 ~2cm,and 3 lesions were >2cm; (5) The boundary of all lesions were clear;The edge of 13 lesions were smooth and 1lesion was aot smooth; (6) The density of 3 lesions were uniform, of which the diameter of 2 lesions were < 1 cm.There were 4 lesions showed a regular cystic zone in the center,and 7 lesions showed a irregular cystic zone in the center;The area of cystic zone were >50%in 5 lesions; (7)All of 14 lesions were enhanced obviously in enhanced CT scans.Increase of CT values were ≥40HU.Conclusion Single less lesions situated in superficial lobe of parotid gland, with clear boundary, smooth edge, cystic zone in the lesions, and enhanced obviously were the CT features of basal cell adenomas.Recognizing this CT features combined with the patients' gender and age could make for a definite diagnosis.
5.Clinical valne of MSCT in diagnosis of cystic masses of neck
Chinese Journal of Primary Medicine and Pharmacy 2011;18(10):1321-1322
Objective To investigate MSCT findings of cystic masses of the neck.Methods The clinical and CT imaging data of 36 cases with cystic neck lesions including 1ymphsdenopathy 9 cases,abscesses 3 cases,salivary lesions 2 cases,thyroid lesions 2 cases,thyroglossal duet cysts 9 cases,branchial cleft cysts 5 cases,cystic hygromas 3 cases,deimoidcyst 1 case laryngeal mucocele 1 case and nerve sheath tumors 1 case comfired by operation-pathology were analyzed.Results The cystic features of lesions could be showed on contrast-enhaced CT,cystic alteration in lymphadenopathy were due to necrosis and presented as the cystic wall enhanced and thickened salivary cystic lesions were variable congenital cystic masses usually appeared as a smooth,well-circum scribed mass,the cystis wall Was thin and nonenhanced unless inflammation was present and most of them localized at the specific anatommic compartments thyroglossal duct cysts were mainly in the anterior midline portion of the neck at the level of the hyoid bone.Second branchial cleft was commonly in the posteriormargin of the subm and ibular gland and lateral to the carotid space.Dermoid cyst presented in the floor of the mouth.Conclusion CT can provide essential infonnatiom in evaluating the nature and location of the cystic mass of neck.which is of significance for diagnosis and preoperative planning.
6.Incentive compatibility of medical workers as the inevitable choice for health reform to succeed
Chinese Journal of Hospital Administration 2013;29(11):840-843
Adherence to public welfare and mobilizing incentives are key to promoting the health reform,and making it a success as well.It is imperative to comprehensively and correctly comprehend the importance of mobilizing medical workers in ensuring the reform a success,based on the present practice of the health reform and by views of philosophy,economics,and management.These principles should be followed in the design and perfection of the reform mechanism.
7.Ganglioside GM1 and central nervous system diseases
International Journal of Cerebrovascular Diseases 2009;17(12):881-888
Gangliosides are sialic acid-containing glycosphingolipids and abundant in the brain. Some studies showed that glycosphingolipids not only could improve the differentiation of neurons, neurite outgrowth and synaptogenesis, but also could modulate neuronal plasticity and improve neurological function after cerebral damage. GM1 was so far most widely studied glycosphingolipids. It is believed that the regulatory functions for calcium homeostasis and the interaction between GM1 and neurotrophins are essential in the mechanisms underlying its neuroprotection. In addition, GM1 has also anti-excitotoxicity, anti-oxidation and vasodilation properties. Various forms of chronic neurodegenerative diseases and hypoxia/ischemic encepha-lopathy are characterized by progressive loss and apoptosis of neurons, the neuroprotective and neruotrophic effects of GM1 could play pivotal role in the treatment of these diseases. Nowadays, GM1 was widely used for the treatment of Parkinson's disease, stroke, hypoxia-ischemic encephalopathy, craniocerebral trauma, spinal cord injury and peripheral neuropathy. Further researches for the mechanisms of GM1 will provide new strategies for the treatment of central nervous system diseases.
8.Influence of lower myocardial infarct patients appeared Ⅲ atrio-ventricular block treatment with thrombolytic recanalization
Chinese Journal of Primary Medicine and Pharmacy 2009;16(5):802-803
Objective To investigate the influence of patients suffered from acute lower wall cardiac infarct appeared Ⅲ atrio-ventricular block tneatment with thrombolytic recanalization for the early recovery of sinus rhythm.Methods From October 01 till October 06, a total of 25 hospitalized patients in our hospital with acute lower cardiac infarct, chest pain persist over thirty minutes, but less than one hour, immediately treatment with urokinase thrombolytic therapy after hospitalization, among them 17 cases reinfusion therapy success ful and 8 cases failed. Divided into reinfusion therapy success group and failed group, observate thromholytic therapy 6 hours recanalization success and fail group the situation of sinus rhythm recovore. Results Among 17 cases recanalization success patients and 14 cases recover sinus rhythm within 6 hours ,and 8 case fail in recanalization 2 cases recover sinus rhythm in 6 hours(25%)compared these two groups statistical are meaningful ( P<0. 01 ). Conclusion Acute lower cardiac infarct patients with Ⅲ atrio-ventricular block must use thrombolytic therapy as soon as possible in order to let oclusive coronary artery recanalize, help to recover sinus rhythm as soon as possible and decrease mortality rate.
9.Anastomotic fistula of esophagus cancer and cardiac cancer
International Journal of Surgery 2008;35(3):162-164
Objective To explore the cause of anastomotie fistula after esophagus cancer and cardiac cancer operation and its prevention and treatment.Methods After excising the tumors,the esophagogastrostomy was performed in 60 cases,in which the cervical anastomose in 48 cases and intrathoracic anastomose was adopted in 12 cases.We retrospectively analyzed its prevention and treatment. Results Caevial anastomose in 48 cases,4 patients with anastomotic fistula in the died,while none of 12 cases in the cervical anastomose died. Conclusions Careful procedure and improving the anastomotic methods are the key factors to reduse the anastomotic fistula,the accurate control of infection and full nutritive support are the effective methods to decrease the mortality rate of this disease.
10.Calcium channels and calcium transport of placenta
International Journal of Pediatrics 2010;37(3):305-307
Calcium metabolism and the transepithelial Ca2+ active transport play important roles in many basic physiological processes,such as neurotransmission,excitation-contraction coupling, vesicular secretion. Placenta is a link between maternal and fetal,transiting all the nutritions from maternal to the fetus.The syncytionbophoblast express many sorts of calcium channels/transporters and exchangers, such as voltage-dependant Ca2+ channels, transient receptor potential channels, store-operated Ca2+ channels, calcium-binding proteins, plasma membrane Ca2+ -ATPases, Na + / Ca2+ exchanger, which exhibit specific distribution and physiological properties. Therefore, this review focuses on the tissue expression and functional properties of channels, transporters,and exchangers in syncytionboph-oblasts.