Congenital hydronephrosis is a common disease in children,causes and pathogenesis re-mains unclear.Hydronephrosis formation process is a slow and gradual development to the dynamic process of renal fibrosis.It involves a variety of cells,cytokines and ECM,more than aspects of interaction and mu-tual adjustment.The study found abroad that CTGF is closely related to the formation of congenital hydrone-phrosis.This article reviews the recent progress made CTGF relationship with congenital hydronephrosis formed on.

Objective To investigate the clinical characteristics and choices of management of neonatal testicular torsion (NTF).Methods Between January 2013 and December 2015,the clinical data of 7 cases of neonatal testicular torsion who were confirmed by surgery and pathological examination in the department of pediatric surgery of our hospital was retrospectively reviewed.Of the 7 NTTs (4 in right,2 in left and 1 in both sides),the median age and onset time of NNTs was 3 d (1-21 d) and 1 d (1-21 d),respectively.The presentation of NTTs included swelling of scrotum,scrotal mass and discoloration of scrotum.Features of ultrasonography included enlargement of testicular volume,echo heterogenicity or enhancement of testis,and decreased or disappeared testicular blood flow.Results All NTTs were performed by surgery and confirmed by pathological examination.In the operation,5 patients with extravaginal torsion (1 bilateral) and 2 with intravaginal torsion were detected.The degree of twisted testis was from 270° to 720°(average 438.8°) and resection rate for necrosis testis was 87.5％ (7/8).The median time of follow-up was 12 months (3-36 months),and none of testis underwent re-torsion and the findings of testicular ultrasonography was not abnormal.Conclusions The presentation of neonatal testicular torsion is non-specific.Once the scrotum shows discoloration,swelling,or enlargement of testis,testicular torsion is suspected.Urgent surgical exploration is recommended in order to make an effort to save the testis.

Coagulopathy after traumatic brain injury is a coagulation dysfunction caused by brain tissue injury, which is characterized by over activations of coagulation, fibrinolysis and anticoagulation. It is the result of the interaction of multiple factors and multiple links with complicated pathophysiology. This study reivewed the clinical features and evidence-based evidences of coagulopathy after traumatic brain injury in order to summarize and discuss the latest progress in the diagnosis and treatment of coagulopathy after traumatic brain injury.

Objective:To understand the influence factors of suicidal ideation among college students of military medical university and to provide reasonable suggestion for preventing suicide among college students.Methods:701 college students were investigated and multiple logistic regression was used to analyse the major influence factors for suicidal ideation Results:Multiple logistic regression analysis shows the major influence factors for suicidal ideation are score,depression,life events and social support.Conclusions:According to the influence factors of suicidal ideation,taking appropriate measures to prevent suicide among college students is an urgent task.

Objective To study the effect of heat treatment with sol-gel method on the surface of Ni-Cr alloy for PFM after Ti coating. Methods To establish the sol-gel method of Ti coating on the surface of Ni-Cr dental casting alloy for PFM(pre-treatment for the surface of Ni-Cr alloy,preparation of sol,coating,heat treatment) and to evaluate the color and fragmentation of 10 materials after heat treatment by ISO 10289. Results When kept at a higher condensation temperature and held for a longer time,the materials had less fragmentation.A higher agglutination temperature and a longer time made the materials look deep.When the condensation process was heat treated at(200 ℃) for 2 h and the agglutination process at 450 ℃ for 2 h,the thin film of Ti combined firmly with the surface of Ni-Cr alloy. Conclusion The procedure for heat treatment of Ti coating will affect the level of oxidation reaction on the surface of Ni-Cr alloy,and will change the level of combination between Ti and Ni-Cr alloy.

Objective To study the effect of Mutans Streptococcus(S.Mutans) on the corrosion resistance of Ni-Cr alloy. Methods S.Mutans were isolated in TSB,and then 10~(5)10~6 CFU/mL of bacterial population was reached.The self-corrosion electrical current density and the corrosion electrical current potential of Ni-Cr alloy were found from polarization curves under the condition with or without media plus S.Mutans.The surface of Ni-Cr alloy after bacterial corrosion was examined with X-ray photoelectron spectroscopy(XPS) to find out different element contents.(Results)From polarization curves,it could be found that the self-corrosion electrical current density and the corrosion electrical current potential of Ni-Cr alloy without S.Mutans were 53.5 ?A/cm~(2)and-62 mV,and those with S.Mutans were 75.7 ?A/cm~(2)and-220 mV.Examination of XPS showed that besides Ni and Cr,the element of chlorine(Cl),sulphur(S),calcium(Ca) could be found on the surface of Ni-Cr alloy after bacterial corrosion.(Conclusion Because of) the metabolism of S.Mutans,an oxide film could be destroyed and a biofilm be formed on the surface of Ni-Cr alloy.Bacterial corrosion could lower the corrosion resistance performance of Ni-Cr alloy.

Carcinoma, Adenoid Cystic ; Female ; Humans ; Laryngeal Neoplasms ; Middle Aged

Objective To investigate the effects of nutritional support on the hypermetabolism of patients with digestive tract fistula complicated with severe abdominal infection. Methods Twenty-nine patients with digestive tract fistula complicated with severe abdominal infection were administered parenteral nutrition (PN) for 4 to 8 days, and then followed by enteral nutrition (EN) or EN + PN. The body weight, serum albumin, transferrin, prealbumin, fibronectin were monitored before and on the 10th and 28th day after nutritional support. Results The levels of serum prealbumin and fibronectin were increased significantly on the 10th day after nutritional support (t = 3.72, 3.52, P <0.01). The body weight, the levels of serum albumin, transferrin, prealbumin and fibronectin were significantly higher than those before nutritional support (t=3.97, 6.57, 7.09, 3.51, 3.58, P<0.01). Conclusion Nutritional support is effective in alleviating hypermetabolism of patients with digestive tract fistula complicated with severe abdominal infection.

Objective To investigate the application and correlation of enterovirus 71(EV71)and Coxsackie virus A16(CA16)antibody screening in the hand,foot and mouth disease(HFMD).Methods The method of enzyme linked immunosorbent assay was used to test the serum antibody of EV71-IgM and CA16-IgM in 281 patients(142 male and 139 female)with HFMD.Results The positive rate of EV71-IgM antibody was 51.2％(144/281),the positive rate of CA16-IgM antibody was 32.0％(90/281).Seventeen patients(6.0％,17/281)had dual positive of EV71-IgM and CA 16-IgM antibody.The total detection rate was 77.2％(217/281).The positive rate of EV71-IgM and CA16-IgM antibody had significant difference(x2 =21.35,P ＜ 0.01).The positive rate of EV71-IgM and CA16-IgM antibody in male had significant difference compared with female[95.1％(135/142)vs.71.2％(99/139),P＜ 0.01].Conclusions At the beginning of the illness should use the joint detection of EV71-IgM and CA16-IgM antibody diagnose HFMD.It has significance in diagnosing and monitoring.

Objective To observe the safety and efficiency of two different ways of intravenous anesthesia combined with oropharyngeal airway ventilation in hysteroscope operation.Methods 40 ASA Ⅰ ～ Ⅱ patients undergoing hysteroscopy were randomly assigned into two groups,20 cases in each group.Patients in the group A,B,were administered respectively with sufentanil 0.1 μg/kg or dexmedetomidine 0.5μg/kg by micro-pump in at least 10 minutes before operation.The perioperative hemodynamic index was recorded.The different outcomes including total dose of propofol,hemodynamic changes,recovery time,postoperative uterine contraction pain and episodes of adverse actions were observed and compared.Results Compared with group A,heart rate (HR) and systolic blood pressure (SBP) were higher in group B (P ＜ 0.05).The recovery time in group A was longer than that in group B (P ＜0.05).But there were no statistical differences of the total dosage of propofol,the incidence of respiratory depression,and the incidence rate of drowsiness after operation betwween group A and group B (P ＞ 0.05).Conclusion There was safe and effective of two different ways of intravenous anesthesia combined with oropharyngeal airway ventilation in hysteroscope operation,but the dynamic index was more stable,and the recovery time was shorter in patients with lowdose dexmedetomidine.