1.Diagnostic value of MDCT in parotid gland basal cell adenoma
Chinese Journal of Primary Medicine and Pharmacy 2011;18(8):1036-1038
Objective To investigate MSCT findings of CT features of basal cell adenomas in the parotid gland, and improve its diagnostic value.Methods 12 cases plain and enhanced CT findings of basal cell adenomas in the parotid gland were retrospectively analyzed for their position, numbers, size, shape, edge, density and enhancement features,which were all verified pathologically after surgery.Results (1) There were 4 males and 8 females, of which 7 females were in the age of 50 ~59; (2) There were 14 lesions in 12 cases,11 cases were single and 1 case was unilateral multiple ( 3 lesions) ; (3) 12 lesions were situated in superficial lobe of the parotid gland, and 2 lesions were situated between superficial lobe and deep lobe of the parotid gland; (4) The maximum diameter of all lesions were <3cm,of which 5 lesions were < 1em,and 6 lesions were 1 ~2cm,and 3 lesions were >2cm; (5) The boundary of all lesions were clear;The edge of 13 lesions were smooth and 1lesion was aot smooth; (6) The density of 3 lesions were uniform, of which the diameter of 2 lesions were < 1 cm.There were 4 lesions showed a regular cystic zone in the center,and 7 lesions showed a irregular cystic zone in the center;The area of cystic zone were >50%in 5 lesions; (7)All of 14 lesions were enhanced obviously in enhanced CT scans.Increase of CT values were ≥40HU.Conclusion Single less lesions situated in superficial lobe of parotid gland, with clear boundary, smooth edge, cystic zone in the lesions, and enhanced obviously were the CT features of basal cell adenomas.Recognizing this CT features combined with the patients' gender and age could make for a definite diagnosis.
2.Clinical valne of MSCT in diagnosis of cystic masses of neck
Chinese Journal of Primary Medicine and Pharmacy 2011;18(10):1321-1322
Objective To investigate MSCT findings of cystic masses of the neck.Methods The clinical and CT imaging data of 36 cases with cystic neck lesions including 1ymphsdenopathy 9 cases,abscesses 3 cases,salivary lesions 2 cases,thyroid lesions 2 cases,thyroglossal duet cysts 9 cases,branchial cleft cysts 5 cases,cystic hygromas 3 cases,deimoidcyst 1 case laryngeal mucocele 1 case and nerve sheath tumors 1 case comfired by operation-pathology were analyzed.Results The cystic features of lesions could be showed on contrast-enhaced CT,cystic alteration in lymphadenopathy were due to necrosis and presented as the cystic wall enhanced and thickened salivary cystic lesions were variable congenital cystic masses usually appeared as a smooth,well-circum scribed mass,the cystis wall Was thin and nonenhanced unless inflammation was present and most of them localized at the specific anatommic compartments thyroglossal duct cysts were mainly in the anterior midline portion of the neck at the level of the hyoid bone.Second branchial cleft was commonly in the posteriormargin of the subm and ibular gland and lateral to the carotid space.Dermoid cyst presented in the floor of the mouth.Conclusion CT can provide essential infonnatiom in evaluating the nature and location of the cystic mass of neck.which is of significance for diagnosis and preoperative planning.
4.Clinical analysis of incomplete Beh et′s disease
Chinese Journal of Ocular Fundus Diseases 2003;0(06):-
Objective To investigate the clinical diagnosis and treatment of incomplete Beh et′s disease. Methods The clinical data of 52 patients (83 eyes ) with incomplete Beh et′s disease were retrospectively analysed. Visual acuity and results of examination of slit-lamp microscope, ocular fundus, and fundus fluorescein angiography (FFA) were observed and analysed. All of patients were treated by local cycloplegic, systemic treatment with glucocorticoid and cytoxan. The followed-up period was 1 year or more. Results Recurrent hypopyon or empyema of anterior chamber angle, and hyperaemia of optic papilla was found in 54 and 41 eyes, respectively. The results of FFA showed that abnormal changes were found in all of the eyes. There was vascular leakage and staining of optic papilla at the early and late stage in 83 eyes (100%), diffuse leakage of retinal capillary vessel in 83 eyes (100%), and leakage of affected branch of retinal vessel and staining of the vascular wall at the late stage in 71 eyes (85.54%).After the treatment, the disease recovered completely in 20 patients (26 eyes), recovered partly in 20 (33 eyes), and alleviated in 12 (24 eyes). No patients suffered from hypopyon or empyema of anterior chamber angle and hyperemia of optic papilla. None of the patients had oral ulcer, genital ulcer or arthritis until the last day of the follow-up. Conclusions Recurrent hypopyon, papillitis, and retinal vasculitis were the main clinical manifestations of incomplete Beh et′s disease. FFA redounds to the diagnosis of the disease and timely application of cycloplegic and systemic application of glucocorticoid and cytoxan may inhibit the aggravation of the disease effectively.
5.Influence of Meretrix Polysaccharides on Immune Functions in the Experimental Diabetic Rats
Journal of Zhejiang Chinese Medical University 2006;0(06):-
[Objective]To study the influence of meretrix polysaccharides on immune functions in the experimental diabetic rats.[Method]The experimental diabetic rats were yielded by streptozotocin(25mg/kg i.v)and fed with hyperotophic foods,then we used meretrix polysaccharides to treat the type Ⅱdiabetes rats and observed erythrocyte immune adherence function and T lymphocyte subsets in the experimental rats.[Results]The erythrocyte C3b receptor ratio(E-C3bRR)decreased 37.92% and the erythrocyte immune compound ratio(E-ICR)increased 64.36%,T lymphocyte subgroup(CD3、CD4、CD8)lowered 25.49%,26.54%,16.85% respectively.All of the above mentioned parameters in the model group were significantly different from that of the control group(P
6.Analysis of rDNA ITS sequences of Radix et Rhizoma Salviae Miltiorrhizae and plants of Salvia L.
Chinese Traditional and Herbal Drugs 1994;0(09):-
Objective To study the genetic diversity of ITS sequences of Radix et Rhizoma Salviae Miltiorrhizae (RRSM) and plants of Salvia L. and analyze the utility of ITS sequences in molecular authentication of RRSM and phylogenetic of plants of Salvia L. Methods The ITS gene fragment was amplified using a pair of primers. The PCR products were purified and sequenced by the methods of Sanger dideoxy. Results The DNA sequence of 222-224 bp ITS1, 220-223 bp ITS2 gene fragments and 5.8S rDNA were obtained from 13 samples of Salvia L. The interspecific substitution varied from 0% to 12.16% at ITS1 and 0.5% to 13.51% at ITS2. The intraspecific substitution of RRSM is 0% to 0.9% at ITS1 and 0% to 0.5% at ITS2. The substitution between group of Salvia L. and outgroup varied from 16.07% to 20.27% at ITS1 and 15.91% to 20.27% at ITS2. The phylogenetic tree based on ITS1 and ITS2 data was set up. Conclusion The ITS1 and ITS2 gene fragments are highly conservative at intraspecific level in RRSM, while they are less conservative at interspecific level in Salvia L. They are least conservative between group of Salvia L. and outgroup. Hence, the sequence of this fragment is a good molecular marker for authentication of RRSM and can be used for further study on the phylogenesis for plants of Salvia L.
7.Measurement of Perihematomal Cerebral Blood Flow in Intracerebral Hemorrhage
International Journal of Cerebrovascular Diseases 2006;0(11):-
Neuroimaging technology is the major means in the study of cerebral blood flow. This article reviews all kinds of neuroimaging technologies in identification of perihematomal penumbra in intracerebral hemorrhage,as well as the research status of perihematomal cerebral blood flow in intracerebral hemorrhage.
8.Clinical observation of trabeculectomy with mitomycin and interferon therapy on neovascular glaucoma
International Eye Science 2015;(1):146-148
?AlM:To understand the clinical effect of trabeculectomy with mitomycin and interferon therapy on neovascular glaucoma.? METHODS: Neovascular glaucoma patients in our hospital from January 2011 to January 2013 were sampled, from them, 57 cases ( 57 eyes ) were randomly divided into two groups, control group received routine trabeculectomy for treatment, the experimental group accepted combination therapy of trabeculectomy +mitomycin + interferon. The clinical efficacy of two groups were observed.?RESULTS:The total effective rate (96%) in experimental group was significantly better than that in the control group ( 76%) , and the visual acuity, filtering bleb and postoperative 1wk, 1a of intraocular pressure changes were better than those of the control group, there was a statistically significant difference (P<0. 05). The rate of complications in experimental group ( 10%) was slightly higher than that of the control group (7%), but there was no statistically significant difference (P>0. 05).? CONCLUSlON: Trabeculectomy combined mitomycin and interferon treatment of neovascular glaucoma has exact clinical effect, and is worthy of clinical popularization and application.
9. Effect of Salvia mildorrhiza extracts on formation of morphine physical dependence in mice and its possible mechanism
Chinese Traditional and Herbal Drugs 2011;42(3):535-537
Objective: To observe the action of Salvia miltiorrhiza extracts (SmE2, liposoluble constituents) on the formation of physical dependence induced by morphine in mice and the effects of SmE2 on the production of cyclic adenosine monophosphate (cAMP) and nitric oxide (NO) in brain of morphine-dependent mice. Methods: Morphine-dependent mice model was established by sc injection of morphine at a gradual increasing dosage. The effect of SmE2 on the withdrawal symptoms induced by Naloxone in morphine-dependent mice was observed. cAMP and NO content in brain were determined through radioimmunoassay and nitrate reductase, respectively. Results: SmE2 (80 mg/kg) could remarkably reduce the withdrawal symptoms in morphine-dependent mice. The cAMP concentration in brain showed no obvious change in morphine-dependent mice treated with SmE2, but NO content in brain could significantly be reduced. Conclusion: SmE2 has effect on relieving the withdrawal symptoms in morphine-dependent mice with down-regulation of NO content in brain as possible mechanism.
10.Research evolution and hotspots of electroencephalogram (EEG) biofeedback in attention-deficit/hyperactivity disorder
Qiang DING ; Wenhai ZHANG ; Qing WEI ; Qiang LIU ; Hong LI
Chinese Mental Health Journal 2017;31(5):418-424
Objective:To review the research hotspots and evolution of electroencephalogram (EEG) biofeedback in attention-deficit/hyperactivity disorder (ADHD) by knowledge mapping software.Methods:Based on web of science core collection database,we searched the literature with keywords (EEG biofeedback OR neurofeedback) AND (ADHD OR attention-deficit/hyperactivity disorder) in topic and time limit set before December 31,2015.319 literature were accepted,using the CiteSpace to depict the hot keywords,cited references and countries.Results:United States of America,Germany,Netherlands were top 3 countries in publishing papers of EEG biofeedback in ADHD.Based on burst of cited references,the research evolution of EEG biofeedback in ADHD could be divided into three stages.The hotspots of EEG biofeedback in ADHD were Slow Cortical Potentials protocol and double-blind placebo-controlled study.Conclusion:Future research should focus on the mechanism of EEG biofeedback and such known protocols for individualized treatment,or be designed along the lines of learning theory.