Anniversaries and Special Events ; Integrative Medicine ; Societies, Medical

OBJECTIVETo investigate the efficacy and action mechanisms of Compound Xuanju Capsule (CXC) in the treatment of type III and type IV prostatitis.

METHODSThis study included 88 cases of type III and 18 cases of type IV prostatitis, 14 with male infertility, 27 with ED, and 8 with increased PSA levels. In addition to prostate massage and psychotherapy, the patients were treated with CXC, 3 capsules once, tid, for 3 months. Then changes in relevant indexes were evaluated by the self-control method.

RESULTSThe NIH-CPSI scores of the patients with type III prostatitis were decreased by 47.59% (22.17 +/- 3.48 vs 1.62 +/- 2.53) after 1 month and by 74.61% (22.17 +/- 3.48 vs 5.63 +/- 3.14) after 3 months of CXC medication, with statistically significant differences from the baseline in both the total score and the scores on specific items (P < 0.05). The patients with infertility showed significantly improved sperm quality after treatment as compared with premedication (sperm cone: [12.52 +/- 3.16] x 10(6)/ml vs [28.32 +/- 8.36] x 10(6)/ml, grade a sperm: [10.12 +/- 4.56]% vs [26.06 +/- 10.18]%, grade a + b sperm: [29.89 +/- 8.86]% vs [53.26 +/- 11.29]%) (P < 0.05), and 8 of the patients' spouses got pregnant. Nineteen of the patients with ED were cured, with significant differences in the IIEF-5 score from pretreatment (10.41 +/- 3.65 vs 19.78 +/- 3.00) (P < 0.05). The PSA level was reduced to normal in all the 8 abnormal cases. The WBC count was remarkably decreased and even returned to normal in 19 cases with WBC count > 100/HP ative culture results.

CONCLUSIONCompound Xuanju Capsule is efficacious for type III and type IV prostatitis and those complicated by infertility, ED, PSA elevation, WBC increase, and negative culture results, with no obvious adverse events.

Capsules ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Infertility, Male ; drug therapy ; Male ; Phytotherapy ; Prostatitis ; drug therapy ; pathology ; Sperm Count ; Spermatozoa ; drug effects ; Treatment Outcome

China ; Health Promotion ; methods ; trends ; Humans ; Integrative Medicine ; methods ; trends ; Medicine, Chinese Traditional ; methods ; trends

Anniversaries and Special Events ; Humans ; Integrative Medicine ; methods ; Learning ; Medicine, Chinese Traditional ; methods ; Physicians

Biomedical Research ; Carcinoma, Hepatocellular ; virology ; Hepatitis B virus ; genetics ; physiology ; Humans ; Liver Neoplasms ; virology

Mild cognitive impairment(MCI)is a new concept put forward in recent years.It is a transtrional state between normal aging and dementia.Prospective studies have shown that the orbebility of the patients with MCI converted to dementia is significantly higher than the normal aged.population.The correct diagnosis of MCI contributes to screen the high-risk population of dementia.It will provide the possibility for preventing dementia and decreasing the morbidity of dementia.

The smooth conversion of scientific achievements in Chinese medicine to standards acts as a bridge in the industrialization process of scientific achievements. By combining scientific researches and standards development of Chinese medicine, this paper analyzed how to establish a mechanism for mutual supports of scientific research and standards development. Based on different categories of scientific achievements in Chinese medicine, this paper ex-plored models for converting fundamental achievements for public wealth and technical achievements for products in-to standards.

Objective To evaluate the capability of SSH/RAD MRH based on SENSE to show gastrointestinal tract anatomic structure,to provide normal anatomic base for gastrointestinal tract disease diagnosis with SSH/RAD MRH and to explore the new examination method for imaging diagnosis in gastrointestinal tract disease.Methods There were 30 healthy volunteers in total including 19 male cases,11 female cases,the age ranging from 20 to 50 with the mean age as 35 year old.All volunteers were asked to drink tap water about 1000-1500mL continuously at 60 minute before examination,to drink tap water 500mL at 20 minute before examination and receive injection of 654-2 10mg in muscle at 10min before examination.MRH were performed by Philips Gyroscan Intera 1.5T superconduct MRI scanner,using SENSE technique,phased-array coil and breath hold.SSH/RAD MRH was performed after the routine abdominal MR scan was done.Results SSH/RAD MRH was successfully performed on all volunteers at one time,and the examination achievement ratio was 100%.All images were evaluated by two senior doctors using blindness method.The ratio of the good-optimal quality images was 93% and the poor-quality images was 7%.Of all images,the stomach manifestation ratio was 65%,the stomach mucous clear manifestation ratio was 80%,the duodenum manifestation ratio was 80%,the jejunum manifestation ratio was 59%,the jejunum diameter was 2-2.5cm,the ileum manifestation ratio was 21%,the ileum diameter was 1.5-2.5cm and the small intestinal mucous clear manifestation ratio was 67%;the colon manifestation ratio was 10% and the colon mucous clear manifestation was 6%.Conclusion SSH/RAD MRH based on SENSE can clearly show the outline and mucous of the stomach,duodenum and jejunum,but can not clearly show the outline and mucous of ileum and colon.The imaging examination that the colon SSH/RAD MRH combined with the routine abdominal MR scan could clearly and conveniently show the anatomical characteristics of gastrointestinal tract.It is a new imaging examination method for gastrointestinal tract examination.

The peptidyl prolyl cis/trans isomerase Pin1 specifically binds phosphorylated Ser/Thr-Pro protein motifs and catalyzes the cis/trans isomerization of the peptide bond,changes the conformation and influences the stability and activity of the substrates.To date,a subset of proteins has been identified as substrates for Pin1.Pin1 interacts with its substrates and plays crucial roles in cell cycle,neural pathology and immune response.Accumulating studies have revealed that Pin1 isomerase activity is regulated by its post-translational modifications,including phosphorylation and oxidation.Over-expression or regulative imbalance of Pin1 plays an important role in the pathogenesis and therapeutics of human diseases such as cancer and AD.

Objective To investigate the clinical and pathological features of children malignant lymphoma.Method A retrospective study was carried out to analyse the clinical,laboratory and pathological data in 65 patients with malignant lymphoma.Results In the chidren malignant lymphoma,the incidence of nonHodgkin′s lymphoma(NHL) was more than that of Hodgkin′s disease(HL),the ratio of NHL to HL was 2.25∶1.The peak incidence of age was among 6 to 9 years old,the ratio of male to female is about(3.5∶1.)NHL of our children was mostly consised of lymphoblastic lymphoma,anaplastic large-cell lymphoma,diffuse large B-cell lymphoma and Burkitt′s lymphoma.The clinical manifestations were predominantly presented with peripheral nodes intumescing,mediastinal tumeur,abdominal tumeur,bone marrow infiltration.In patients with Hodgkin′s disease,mixed cellularity was the most common pathological category,and cervical painless lymphadenectasis was usually the initial signs in most patients,sometimes accompanied with infiltration of celiac lymph nodes,spleen and bone marrow.Conclusions NHL of our children differs from that of adult in the clinical feature and pathology,while HL of our patients is similar to adults.Since the prognosis of the malignant lymphoma is determined by its pathology,immunohistochemistry plays an important role in the diagnosis and differential diagnosis.J Appl Clin Pediatr,2006,21(3):160-161