Objective To explore the treatment resection-line involvement gastric cancer.Method The relationship between resection-line involvement and outcome was evaluated in patients underwebt potentially curative resection for gastric cancer.Results Tumor positive resection-lines were found in 22 of 237 patients (9.3%).Resection-line involvement was associated with tumor location (P=0.01) and tumor differentiation (P =0.02).Positive margins were associated with worse survival.However,according to lymph node metastases,resection line involvement determined a shorter survival only in patients with N 0 stage disease.Conclusion The re operation should be considered only for patients with N 0 stage disease,while patients with metastatic lymph nodes do not need a more aggressive surgical approach.