1.EXPERIMENTAL STUDIES OF SPIRULINA COMPOUND TABLET ON HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS
Chinese Journal of Marine Drugs 2000;0(06):-
With the doses of Spirulina compound tablet (FST) 1.5g?kg 1 ,3g?kg 1 by ig administration to normal rats,alloxan (ALX) induced diabetic rats and hyperlipidemic model rats respectively for 14 days ,then the fast blood glucose(FBG) and the serum lipids were detected.The results showed that FST could decrease the FBG and the serum TC,TG,LDL C,increase HDL C in normal and in diabetic rats.(But FST 1.5g?kg 1 had no significant effect on TG,HDL C in normal rats).In addition,it was found that FST could remarkably decrease the level of serum TC,TG, and LDL C,as well as increase HDL C in hyperlipidemic model rats.It is suggested that FST not only significantly decrease the FBG and the lipids contents both in normal and in diabetic rats,but also remarkably decrease the serum lipids level in hyperlipidemic model rats. [WT5HZ]
2.The transformation and adaptation of medical English terms in Chinese language and culture
Wei LIU ; Qian WANG ; Xiaodan ZUO
Chinese Journal of Medical Education Research 2011;10(11):1393-1395
Based on the word-formation of Medical English terms,this paper gives a comprehensive analysis of their transformation and adaptation in Chinese language and culture.Three major factors are discussed for the application and diversification of medical English terms,including the language family in translation,linguistic context,situational context and cultural context.
3.A Study on the awareness of HIV/AIDS and risk behaviors among migrant workers at construction sties in Beijing
Qian ZUO ; Huanbo XIAO ; Guangliang SHAN
Chinese Journal of AIDS & STD 2007;0(05):-
Objective To investigate the awareness of HIV/AIDS and risk behaviors among migrant workers at construction sites in Beijing. Methods The methods of cluster sampling was employed,a questionnaire survey was administered among 1000 migrant workers from two construction sites and a face-to-face interview with the informed consent was conducted in a limited scope.Results There was considerable disparity in the awareness of the routes of AIDS transmission;66.8% of the migrant workers were aware that the condom could reduce the risk of infection,but 51% of them had never used it.Only 2.3% of the migrant workers had sexual intercourse with female sex workers.Conclusion Although the migrant workers under survey have some basic knowledge on HIV/AIDS,their essential understanding was mostly vague,and financial condition have restricted to a great extent their risk behaviors.
4.Lipid Metabolism of Inpatients with Essential Hypertension
Qian GE ; Junli ZUO ; Shaoli CHU
Chinese Journal of Hypertension 2007;0(02):-
Background Hypertension and dyslipidemia are the 2 important risk factors of cardiovascular affecting the prognosis of cardiovascular disease. However paucity data of characteristics of lipid metabolism and prognosis of cardiovascular diseases in high-risk groups with hypertension are available. Objective To analyze the lipid metabolism level and the relevant risk factors of inpatients with essential hypertension (EH) from 2000 to 2007. Methods Retrospective study was performed based on the clinical characteristic and the relationship between different kinds of hyperlipidemia and target organ damages in inpatient with EH. Results For the level of triglyceride (TG) and the prevalence of hypertriglyceridemia,males(n=3056) were significantly higher than females(n=1932)(P
5.Study on expression of stem cell marker SALL4 gene in cervical cancer
Ming ZHANG ; Yiming ZHANG ; Wei ZUO ; Hui QIAN ; Wenrong XU
Chongqing Medicine 2014;(3):285-287
Objective To research the expression and clinical significance of SALL 4 gene in cervical cancer .Methods The ex-pression of SALL4 in 56 samples of cervical cancer and 35 samples of normal cervical tissues was detected by immunohistochemistry and RT-PCR ,and its relationship with the clinicopathological characteristics of cervical cancer was analyzed .Results The expres-sion of SALL4 mRNA was 2 .56 ± 0 .22 in cervical cancer tissues ,which was significantly higher than 0 .38 ± 0 .03 in the normal cer-vical tissues .the difference between them had statistical significance(t=58 .1 ,P<0 .01);the positive expression rate of SALL4 pro-tein was 80 .4% (45/56) in cervical cancer ,which was significantly higher than 11 .4% (4/35) in the normal cervical tissues (χ2 =41 .177 ,P<0 .01) .The positive expression of SALL4 in the cervical cancer tissues was correlated with the differentiation status of tumor ,which in the middle and high differentiation groups was lower than that in the low differentiation group (χ2 =4 .226 ,P=0 .039) ,but had no correlation with age ,International Federation of Gynecology and Obstetrics (FIGO) stage ,tumor size ,pathologi-cal type and lymph node metastasis(P>0 .05) .Conclusion SALL4 is highly expressed in the cervical cancer tissues and correlated with the tumor differentiation ,which might play an important role in the occurrence and development of cervical cancer .
6.Analysis of the correlation among electrocardiogram,echocardiography and three vessel coronary artery disease
Qian YU ; Li LI ; Xiuying ZUO ; Jun ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2015;(19):2910-2912,2913
Objective To further recognize the coronary artery three vessel disease by studying the abnormal change of the electrocardiogram(ECG)and echocardiography of ischemic heart disease patients and unstable angina pectoris patients,and to analyze the results of coronary angiography.Methods Coronary arteriography for 2 654 patients diagnosed as ischemic heart disease,unstable angina pectoris,were conducted and the result of coronary arteriography were compared with the ECG and echocardiography.Results There were certain statistically significant correlation among the ECG,echocardiography abnormal change and three vessel coronary artery disease(ECG:χ2 =9.02,P <0.01;echocardiography:χ2 =14.36,P <0.01).The sensitivity,specificity,false positive rate,and false negative rate of ECG were 71.46%,27.47%,62.26% and 28.50% respectively.The sensitivity,specificity,false positive rate, and false negative rate of echocardiography were 61.27%,27.08%,72.91% and 38.72% respectively.ECG′s change of patients appear in 8 or more leads when angina pectoris attacks exist,the incidence of chest lead terminal positive T wave were higher than 90.00%.Ⅲ lead fQRS wave group or low voltage changeed and AVR lead ST seg-ment elevation were accounting for 82.61% and 56.52% respectively.Conclusion There are certain correlation and predictive value among the ECG,echocardiography and three vessel coronary artery disease.There are characteristic waveform change of ECG when angina pectoris attacks exist.
7.Effect of contact system in monocyte adhesion induced by urokinase-type plasminogen activator
Jianxia LIU ; Jianling ZUO ; Lei QIN ; Haixin QIAN ; Jianning LIU
Chinese Journal of Pathophysiology 1986;0(03):-
AIM:To study the effect of contact system in monocyte adhesion induced by urokinase-type plasminogen activator (U-PA). METHODS:U937 cells were labeled with [3H] thymidine in the culture medium, test reagents were added into the cell suspension in 24-well plates. The counts?min -1 were counted in a liquid scintillation counter. RESULTS:U-PA-induced monocyte adhesion was inhibited by high-molecular-weight kininogen and kallikrein, and promoted by factor Ⅻ and plasminogen. CONCLUSION:these contact system proteins may be important modulators of U-PA-induced monocyte adhesion, a process which is involved in many pathophysiological events.
8.Research progress on the protective effect of exercise on retinal cells and functions
International Eye Science 2021;21(3):450-454
Physical exercise is a low-cost, easy-to-implement therapeutic intervention. In recent years, it has been found that exercise has a protective effect on retinal diseases such as diabetic retinopathy, age-related macular degeneration and retinitis pigmentosa. The mechanism may be related to enhancing retinal defence against oxidative stress, reducing glutamate secretion and inhibiting retinal cell apoptosis through BDNF/TrkB pathway. This paper reviews the recent literature related to the protective effect of exercise on retina from animal experiments, clinical studies and mechanism investigation.
9.Applied research on new type of lighted surgical aspirator in deep brain hematoma removal
Shangjun CHEN ; Chao QIAN ; Haiyan WANG ; Yi ZUO ; Guang CHENG ; Pengfang WEI
Chinese Medical Equipment Journal 2017;38(2):89-91
Objective To explore the application effect of a new lighted surgical aspirator in deep brain hematoma removal operation.Methods Totally 153 patients of non-traumatic basis festival area cerebral hemorrhage were randomly divided into a control group and a treatment group.Both the groups underwent clearance of intracranial hematoma and decompressive craniectomy surgical operation in the operating room,with the common aspirator involved in the control group and the lighted one in the treatment group.Results There was no significant difference between the rates of hematomal removal in the groups (P>0.05).The treatment group had the operating time less by 59.85 min and the hospital stay decreased by 15.23 d than those in the control group (P<0.05).The GOS score and daily viability of the treatment group was also statistically higher than those of the control group (P<0.05),and the effective rate in the treatment group was also more than that in the control group by 24.9% (P<0.05).Conclusion The new aspirator solves the problems in visual field and light source,decreases the operating time and improves the disease prognosis.
10.Gender difference in clinical features and outcomes of elderly patients with coronary true bifurcation lesions after percutaneous coronary intervention
Fang WANG ; Changpeng ZUO ; Jing ZONG ; Fangfang LI ; Luhong XU ; Hui YONG ; Jiali LIU ; Wenhao QIAN
Chinese Journal of Interventional Cardiology 2017;25(3):153-157
Objective To explore the gender difference in clinical features and outcomes of elderly patients with coronary true bifurcation lesions after percutaneous coronary intervention (PCI).Methods A total of 169 consecutive patients were included in the study, who were diagnosed coronary true bifurcation lesions by coronary angiography (CAG)and received PCI in our hospital from December 2013 to December 2015.All patients were divided into 2 groups according to their gender (71 femals and 98 males).Angiographic characteristics of the coronary lesions and clinical data were analyzed in both groups.Clinical outcomes during follow up were recorded and studied.Results The levels of total cholesterol (TC), triglyceride (TG),high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) in the female group were significantly higher than in the male group (all P<0.05).The levels of BUN,Cr,UA,CyC and TBIL in the female group were significantly lower than in the male group (all P<0.05).Comorbidity rates of hypertension and diabetes were higher in female patients without significant differences (P>0.05).The median follow-up time was 17 months and the incidence rate of overall adverse events in women was higher than that of men (25.4% vs.11.2%, P<0.05).Conclusions The clinical outcomes of elderly patients with coronary true bifurcation lesions after PCI had gender differences.The rates of adverse events in female patients was found significantly higher than male patients.