Rhizoma Drynariaed is commonly used for orthopedics, and the chemical composition mainly were flavonoids, triterpenoids, and phenolic glycosides, etc.It has good bioactivity of healing, anti-osteoporosis, anti-inflammatory activity.This paper reviewed the research on chemical constituents and pharmacological activities of Rhizoma Drynariae at home and abroad in recent years, lay the foundation for the further research and development activity of Rhizoma Drynariae.