1.Signal mining and analysis of adverse drug events for gilteritinib
Yang LIU ; Minzhen HAN ; Jie XIA ; Hanshuai HU ; Lei YAO ; Xue LAN ; Qian LIU ; Jinxingyi WANG
China Pharmacy 2024;35(15):1888-1892
OBJECTIVE To mine the adverse drug events (ADE) signals for gilteritinib, and provide a reference for safe drug use in clinic. METHODS ADE reports with gilteritinib as the primary suspected drug were extracted from the FDA Adverse Event Reporting System (FAERS) database from February 1st, 2018 to December 31st, 2023. Reporting odds ratio (ROR) and proportional reporting ratio (PRR) were applied to detect the risk signals from the data in the FAERS database. The classification and statistics of collected signal data were conducted by using the preferred term (PT) and systemic organ class (SOC) in ADE terminology set of the Medical Dictionary for Regulatory Activities (24.1 edition). RESULTS Totally, 2 755 gilteritinib-related ADE reports were collected from the database, involving 676 ADE signals (95 positive signals), 313 PTs and 25 SOCs. Among them, nine signals were not recorded in the package insert. The top 5 PTs consisted of abnormal liver function, decreased platelet count, febrile neutropenia, pneumonia and myelosuppression. The top 6 SOCs for positive signal counts were examinations, general disorders and administration site conditions, respiratory, thoracic and mediastinal disorders, infections and infestations, heart organ disorders, and nervous system disorders. ADEs not recorded in the drug package insert included pneumonia, myelosuppression, decreased blood cell count, sepsis, hemorrhage, infection (not specifically referred to), septic shock, respiratory failure, and aspergillosis. CONCLUSIONS In addition to paying attention to common ADEs such as liver dysfunction and thrombocytopenia, it is necessary to monitor ADEs with strong signals that are not mentioned in the drug instructions when using gefitinib, such as pneumonia, bone marrow suppression, cytopenia, sepsis, bleeding, infection (not specifically referred to), septic shock, respiratory failure, Aspergillus infection, elevated serum creatinine and interstitial lung disease.
2.Research progress on food literacy assessment tools for children and adolescents
QIAN Jinwei, TONG Yingge, PAN Xiang, YAO Lan, NI Ke, XIN Mengyu, CHENG Wenqian, HU Yuying
Chinese Journal of School Health 2024;45(6):891-894
Abstract
As dietary issues of children and adolescents become increasingly complex, the assessment of food literacy (FL) is increasingly importance. FL involves a comprehensive cognition and practical ability concerning food among children, playing a key role in fostering healthy eating habits and improving health levels. The article explores the definition and connotations of FL, and introduces eight FL assessment tools in terms of theoretical foundations, dimensions, assessment methods, and their reliability and validity. Moreover, it provides a comparative analysis of these tools by examining their dimensional design, evaluation indicators, strengths, and weaknesses, as well as their applicable subjects and scenarios, aiming to offer references for implementing relevant policies and developing more comprehensive and effective FL assessment tools.
3.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
4.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
5.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
6.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
7.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
8.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
9.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.
10.Research on New-quality Productivity Empowers the Construction of Healthy China
Chenxi LIU ; Qian WANG ; Lan YAO
Chinese Health Economics 2024;43(7):6-9
Currently,China needs to comprehensively understand the theoretical support,historical experience,and practical requirements of new productive forces to support the construction of Healthy China,accurately grasp its core concepts and profound implications,clarify the strategic direction of new productive forces to support Healthy China,scientifically plan and implement precise measures,in order to find the best practice path for new productive forces to drive high-quality development of a Healthy China.


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