Recent studies suggest that lacunar infarction is a high risk ischemic cerebrovascular disease highly correlated with the time, which optimistic prognosis is not as good as previously thought.In addition, the role of macrovascular diseases has not been paid attention, it is not conducive to secondary prevention and early intervention for the etiology of lacunar infarction.This review focu-ses on application of imaging diagnosis of lacunar infarction, the etiology of non-lacunar infarct, and differential diagnosis of lacunar in-farction.

Wound healing in the human cornea has distinctive characteristics in comparison to most other tissues in the body.The corneal wound healing response is a remarkably complex cascade mediated by cytokines,growth factors,and chemokines.The interactions in the epithelial,stromal,neural,lacrimal gland,immune cells are interwoven in the corneal response to injury.Corneal epithelial cells and basement membrane play important roles in this process.However,both of them are usually impaired during the procedures of excimer laser refractive surgery for myopia,hyperopia,or astigmatism,and complications such as overcorrection,undercorrection,regression,refractive instability,and haze may occur after surgery.A complete corneal wound healing process,the biologic and molecular processes that contribute to the healing response,and anomalies that lead to complications are critical for improving the efficacy and safety of excimer laser refractive surgical procedures.

Objectives:To research the relation of high blood glucose,GCS and prognosis after craniocerebal injury.　Methods:63 patients were divided into three groups,“GCS” 3～8,“GCS” 9～12,and GCS 13～15.Blood glucose of these groups were tested at admission of all patients and one week after hosptialization.　Results:The level of blood glucose and the mortality in GCS 3～8 group were significantly high than those in the other two groups.　Conclusions:After cranidcerebral injury,the blood glucose is an index of the injury degree.We should try to control the blood glucose in normal levels to improve the prognosis of patients with craniocerebral injury.

Objectives:To research the relation of high blood glucose,GCS and prognosis after craniocerebal injury. Methods:63 patients were divided into three groups,“GCS” 3~8,“GCS” 9~12,and GCS 13~15.Blood glucose of these groups were tested at admission of all patients and one week after hosptialization. Results:The level of blood glucose and the mortality in GCS 3~8 group were significantly high than those in the other two groups. Conclusions:After cranidcerebral injury,the blood glucose is an index of the injury degree.We should try to control the blood glucose in normal levels to improve the prognosis of patients with craniocerebral injury.

Through a systematic review and analysis on the related literature and guidlines at home and abroad on the prehabilitation of gastrointestinal neoplasms, this paper sorts out the implementation contents and evaluation methods of the trimodal prehabilitation which includes three aspects: exercise, nutrition and psychology, and found that there is still not standardized content at present. This paper provides the foundation for later evidence-based research. And designed to provide evidence for trimodal prehabilitation nursing practice content, in order to promote the enhanced recovery of the patients with gastrointestinal neoplasm after surgery better.

Objective: To investigate the effect of n-butanol fraction from Elaeagnus pungens leaves (BFEP) on the contraction of isolated guinea pig tracheal smooth muscle under the basal tonus or spasmogens. Methods: Guinea pig tracheal smooth muscle spiral strips were isolated. Under the normal state or the condition treated with acetylchohne (Ach), histamine (Hist), or KCl, Ca2+ release in cells without calcium, and extracellular Ca2+ influx at the high concentration of Ca2+, the effect of BFEP on the tension of isolated trachea was observed. Results: BFEP relaxed the tracheal strip significantly in the concentration-dependent manner under the basal tonus. The tested drug produced an unparallel rightward shift of the cumulative concentration-response curve of Hist or Ach. The contraction induced by high K+ and extracellular Ca2+ influx was inhibited. Conclusion: BFEP could inhibit the contraction of isolated guinea pig tracheal smooth muscle under the basal tonus or spasmogens.

Objective To study the MRI findings in a series of intracranial hemangiopericytomas, and to compare these findings with those of intracranial meningiomas. Methods The MRI appearances and clinical features in 27 cases of intracranial hemangiopericytomas and 236 cases of intracranial meningiomas were retrospectively reviewed. All cases were proved by operation and pathology. The data were evaluated by using ? 2 test, rank sum test, and Logistic Regression. Results Sex (? 2=6 981), shape of tumor (? 2=39 949), signal voids of vessel in tumor (? 2=12 366), necrosis or cystic degeneration in tumor (? 2=37 432), the type of dural attachment ( broad based or narrow based ) (? 2=16 956), T 1WI signal intensity (? 2=14 880), T 2WI signal intensity (? 2=37 068), enhanced degree of tumor (? 2=10 081), homogeneous degree of tumor after contrast enhancement (? 2=17 014), and duration time were significant different ( P

Objective To study the MRI findings of spinal hemangioblastomas.Methods The MRI findings of spinal hemangioblastomas proved pathologically in 29 cases (20 males,9 females) were retrospectively reviewed.Results The lesions were single in 12 cases (41.4%) and multiple in 17 cases(58.6%).Seven patients combined with intracranial hemangioblastomas.On unenhanced MRI,36 tumors were isointense on T 1WI and T 2WI,16 were mixed iso-hypointense on T 1WI and mixed iso-hyperintense on T 2WI,one was hypointense on T 1WI and hyperintense on T 2WI.Small hemangioblastomas tended to be isointense on T 1WI and T 2WI.After contrast injection,all tumors enhanced markedly and homogenously with clear borders.21 tumors in 17 patients had associated vascular flow voids on T 2WI.40 tumors in 27 patients were associated with syringes or cysts.Conclusion Hemangioblastomas of the spinal cord are often multiple and in company with intracranial hemangioblastomas.The marked contrast enhancements with clear borders and associated vascular flow voids are the most important signs on MRI.

Colonic neoplasms is the third most commonly diagnosed cancer in men and second most commonlv diagnosed cancer in women worldwide.The morbidity of Colonic neoplasms is increasing year by year.Despite the fact that surgery is still the main treatment for patients with colon cancer,surgery alone hasn't improved the treatment effectiveness.The current management of colon cancer has come to multidisciplinary team (MDT) modality.MDT modality could offer the optimal treatment option and the internal communication.Under the pattern of MDT which integrates the surgery,chemotherapy,radiotherapy,interventional therapy,targeted therapy and immune therapy,there has been a big progress in the diagnosis and treatment of colon cancer.Patients with metastatic colon cancer should undergo a discussion by a multidisciplinary team before the initial treatment.

Objective To evaluate the therapeutic effect of the jejunal interposition reconstruction type Ⅰ and Ⅱ after total gastrectomy in patients with gastric carcinoma.Methods 31 cases of gastric carcinoma operated were retrospectively analyzed, 16 patients after total gastrectomy were reconstructed to have a jejunal interposition type Ⅰ and 15 a jejunal interposition reconstruction type Ⅱ. The clinic data of the two types jejunal interposition reconstruction were assessed during 6 months ～5 years follow-up. Results 30- 60 minutes and 80-120 minutes barium agent emptying time of type I and II were 62.5%,66.7% and 37.5%,33.3% respectively;normal diet regimen(4～6 meals/d)was recovered,plasma total protein 56～75g/L accounted for 74 2%(23/31),46～56g/L accounted for 25 8%(8/31).Hemoglobin 110～160g/L accounted for 38 7%(12/31) 96～105g/L accounted for 61 3%(19/31).Mean body weight was decreased by 3～5kg in all groups.9 cases recovered eight physical strength labor.The visick scoring of the 87 7% patients with type I and the 86 7% patients with type II was I-II grades. Reflux oesophagitis of the patients with type I was 12 5%. Conclusions The jejunal interposition reconstruction type Ⅰ and Ⅱ is suitable reconstruction after total gastrectomy to improve quality of life and to reduce complications and to maintain the canal of the chyme through the duodenal tract.