A L-arginine-producing mutant UN100-12(SG~(r),AE~(r)) was derived from Corynebacterium glutamicum ATCC138761 by combination treatment with ultraviolet(UV) and N-methyl-N-nitro-N-nitrosoguanidine(NTG). It could accumulate 16.6g/L L-arginine in the medium containing glucose as carbon source and ammonium sulfate as nitrogen source, when it was culrured at 30℃ for 4 days. And also this mutant has good stability of descendiblity of L-arginine.

Recent studies suggest that lacunar infarction is a high risk ischemic cerebrovascular disease highly correlated with the time, which optimistic prognosis is not as good as previously thought.In addition, the role of macrovascular diseases has not been paid attention, it is not conducive to secondary prevention and early intervention for the etiology of lacunar infarction.This review focu-ses on application of imaging diagnosis of lacunar infarction, the etiology of non-lacunar infarct, and differential diagnosis of lacunar in-farction.

Objective:To evaluate the diagnostic value of 18G and 16G needle biopsy of breast lesions.Methods: Onr hundred and fifteen patients with breast lesions those were excised through surgery. Each lesion was under ultrasound-guided needle biopsy(US-CNB) with 18G and 16G, then underwent surgical resection of mass and pathological histology. Histological findings of US-CNB and the surgical specimens were analyzed for sensitivities, false negative rates, and underestimate rates.Results: Among 84 cases of breast cancer proved by surgical pathology, the sensitivity, specificity, false negative rate of 18G and 16G biopsy diagnosis were followed by 95.2% and 97.6%, 89.6% and 94.3%, 4.8% and 2.4%. Paired chi-square test showed no significant difference between the two methods.Conclusion: 18G and 16G needle biopsy has no significant difference in the diagnosis of breast lesions.

Objective To probe into the chnical value of strain rate imaging on the assessment of left atrial function in patients with hypertensive disorder comphcating pregnancy(HDCP).Methods Thirty two patients with HDCP and 20 control subjects were involved.Patients with HDCP were divided into 2 groups:17 with normal left ventricular mass index (LVMI) and 15 with left ventricular hypertrophy.These patients and controls underwent transthoracic echocardiography,strain and strain rate imaging examination.Atrial strain and strain rate imaging values of patients with HDCP were compared with those of controls.Multiple parameters were compared by one-way anova analysis.Results When compared with the controls,peak early diastolic strain rate (ESR) was significantly decreased in HDCP patients with normal LVMI and left ventricular hypertophy [(-1.13 ± 0.15),(-1.04 ± 0.29) s-1 vs.(-1.26 ± 0.23) s-1,P ＜ 0.05].Compared with the normal LVMI,peak late diastolic strain rate (ASR) was significantly decreased in controls and patients with left ventricular hypertrophy [(-1.23 ± 0.25) s-1 vs.(-1.36 ± 0.33),(-1.34 ± 0.32) s-1].There was no significant difference in the others (P ＞ 0.05).Conclusion Left atrial function is decreased in HDCP patients,which with left ventricular hypertrophy,the tendency is more obvious.

As an important device of modern medical treatment,medical monitor is a combination of modern electronics technology,computer technology and medical technology.In this paper,the development of medical monitors in China is summarized,especially the main technique characteristics of medical monitor in Chinese market.The examples of monitors made in China are presented.

Chronic Periodontitis ; therapy ; Dental Implantation ; Dental Scaling ; Humans ; Male ; Middle Aged ; Oral Hygiene ; Periapical Periodontitis ; therapy ; Root Planing ; Tooth Extraction

Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Molar ; Root Canal Therapy ; methods

Antigens, CD34 ; metabolism ; Choriocarcinoma ; pathology ; Diagnosis, Differential ; Female ; Hemangioma ; metabolism ; pathology ; Humans ; Keratin-18 ; metabolism ; Mesenchymoma ; pathology ; Placenta ; pathology ; Placenta Diseases ; metabolism ; pathology ; Platelet Endothelial Cell Adhesion Molecule-1 ; metabolism ; Pregnancy ; Pregnancy Complications, Neoplastic ; metabolism ; pathology ; Young Adult

Objective To establish the CT criteria of quantitative diagnosis for liver steatosis by means of studying the CT features of fatty liver cases proven histologically. Methods Twenty-eight cases of fatty liver were underwent non-enhanced CT scan, and the attenuation of liver parenchyma was measured. To differentiate the degree of fatty liver, the mean CT value and the relative density of hepatic vessels were observed. The quantitative diagnosis was made according to the CT number threshold and the criteria of relative density of hepatic vessels, respectively. Results Among the 28 cases, there were 17 cases of mild steatosis with mean CT number of 46 HU (32-65 HU), 7 cases of middle degree fatty liver with mean CT number of 28 HU (15-38 HU), and 4 cases of sever fatty liver with mean CT number of 0.2 HU (-7-11 HU). For the relative density of hepatic vessels, 16 of the 17 cases of mild fatty liver had a appearance of hepatic vessels immersion and 1 mild case had reverse hepatic vessels display, 6 of 7 middle degree cases had reverse hepatic vessels display with 1 case having the appearance of hepatic vessels immersion, and all the 4 case of sever steatosis had the appearance of reverse hepatic vessels display with sharp contrast between vessels and the liver parenchyma. The accuracy of quantitative diagnosis was 65.9% and 93.1% by means of criteria of CT number threshold and relative density of hepatic vessels, respectively (? 2=7.153,P