2.Clinical and imaging features of primary lateral sclerosis
Journal of Clinical Neurology 2001;0(05):-
Objective To explore the clinical and imaging features of primary lateral sclerosis(PLS).Methods The clinical and imaging data of 3 patients with PLS were analysed.Results 3 patients included 2 females and 1 male.The onset of the disease was insidious.The initial symptoms included rigidity and weakness of right upper limb(case 1),rigidity and weakness of legs(case 2),and pseudobulbar palsy(case 3). As the disease progressed slowly,the patients presented with spastic paralysis of four extremities,reduced muscle strength(3 to 4 degree),clasp-knife like of muscular tension,hyperactivity of tendon reflexes,ankle clonus and presence of Babinski sign.In T2-weighted images of the brain MRI,the abnormal high signals were symmetrically situated in the motor cortex,the posterior limbs of internal capsules,cerebral peduncles and basilar part of pons.1H magnetic resonance spectroscopy(1HMRS) showed decreases of N-acetylasartate(NAA) and the ratio of N-acetylaspartate/Creatine(NAA/Cr) in the focal regions.Conclusion PLS presents with characteristic features of clinical symptoms,signs and abnormal changes of MRI.In addition,1HMRS may be helpful in diagnosis of this disease.
3.Design of electro-acupuncture stimulator for hemiplegia rehabilitation
Xuemin WANG ; Qi WEN ; Shunyao MA
Chinese Medical Equipment Journal 1989;0(03):-
An electro-acupuncture stimulator for hemiplegia rehabilitation is designed, which adopts 51 series of SCMs and CPLD as the control unit to fulfill parameter setup, numerical display and separated multi-channel output.
4.Evaluation of "free sacro-capsule"for the tethered spinal cord syndrome by urodynamic examination
Lin QI ; Jianguo WEN ; Qingwei WANG
Orthopedic Journal of China 2006;0(11):-
[Objective]To use urodynamic method to evaluate "free sacro-capsule"pre-operation and post-operation effect,also evaluate bladder and urethral function.[Method]Twenty children were included in this study.[Result]All children had none damage after operation.The PVR and DLPP of post-operative group are significantly decreased.The BC and MCC of post-operation group was significantly higher than pre-operation group(P
6.Acupuncture for infantile diarrhea.
Chinese Acupuncture & Moxibustion 2013;33(9):773-773
7.Application of high frequency color Doppler ultrasonography in emergency operation of flexor tendon injuries in the hand
Wen LI ; Jie QI ; Yanjie LIU ; Jianhong LIANG ; Chensheng WANG
Chinese Journal of Interventional Imaging and Therapy 2010;7(2):167-170
Objective To observe the value of the high frequency color Doppler uItrasonography in emergency operation of flexor tendon injuries in the hand.Methods Totally 21 patients of flexor tendon injuries in the hand underwent surgical exploration with high frequency probe.The extent of the tendon injuries,the retracted parts of the ruptured tendon and the blood supply were observed.Results The extent of the tendon injuries,the poison of broken ends were clearly distinguished with high frequency probe.The continuous tendon fibrous of layered high echo and sheath thin layer low echo complete broke and replaced with low or no echo.Conclusion Intraoperative uhrasonography of flexor tendon iniuries is important tO shorten operation time,reduce the injury of surrounding tissues,relieve local adhesion and ensure vascular recanalization after operation.
8.A review of research on the development of instruments for therapeutic efficacy evaluation of traditional Chinese medicine.
Weihua XU ; Zehuai WEN ; Weixiong LIANG ; Qi WANG
Journal of Integrative Medicine 2012;10(7):726-37
Due to the differences between Chinese and Western cultures, Chinese version of foreign research instruments may not be totally applicable for use in evaluating the therapeutic effect of traditional Chinese medicine (TCM). Great efforts have been made by Chinese researchers to develop scales for evaluation of the therapeutic effects of TCM. This study aims to understand the current situation of research in the development of evaluation instrument in TCM.
9.The analysis on clinical data of 22 patients with preliminarily diagnosed islet cell adenoma
Wen WANG ; Xiulan ZOU ; Jianming YANG ; Qi HUANG ; Yanqun LIU
Chinese Journal of Postgraduates of Medicine 2009;32(z1):11-12
Objective To study and evaluate islet cell adenoma of preliminary diagnosis.Method Retrospective analysis Wag done on 22 patients clinical data of preliminarily diagnosed islet cell adenoma.They were divided into two groups according to final diagnosis,group of islet cell adenoma(n=16)and group of reacfional hypoglycemia n=6).Results There were significant differences between the two groups in term of fames,cold sweat,cataphora,Whipple triad,hungry test,the ratio offasting blood insulin and fasting blood glucose exceeding 0.3 (I/G>0.3) (P<0.05).No statistical differences were found on blood glucose level in hypoglycemia onset,psychiatric symptom.Conclusion The clinic data is helpful for preliminary diagnosis,and Whipple triad,hungry test,I/G>0.3 above all.
10.Inhibition of growth of human neuroblastoma in nude mouse models by antisense VEGF_(165) cDNA transfection
Mingjie WEN ; Shentao LI ; Yamei WANG ; Yahui QI
Basic & Clinical Medicine 2006;0(11):-
Objective To investigate the inhibitive effect of antisense VEGF165 cDNA on growth and angiogensis of human neuroblastoma in nude mouse models.Methods Three kinds of SH-SY5Y cells which had been stably transfected by sense VEGF165 cDNA,antisense VEGF165 cDNA and empty vector respectively,were inoculated subcutaneously to nude mice.The size of subcutaneous tumors was measured,and the morphology of tumor tissue was observed by microscope.The microvessel density(MVD)in tumor mass was analyzed by CD31 immunohistochemistry staining.Apoptotic cells were detected by the electron microscope.Results The growth of tumor mass,which was inoculated with antisense VEGF,significantly decreased in nude mice compared with empty vector group(P