Objective To evaluate the clinical values of(M-slice computed tomography coronary angiography(CTCA) in contrast to conventional coronary angiography(CCA).Methods Assessment of the major and minor branches of coronary arteries by 64-Slice CTCA,showed the information of 100 patients with 64-slice CTCA,comparing with CCA regarded as the golden standard recently implemented.Results Among the 100 patients,920 coronary arteries were evaluated with 370 lesions found.Of them ,348 lesions were consisted with CCA,22 lesions were falsely positive and 10 lesions were found by CCA not picked up by 64-slice CTCA.The sensitivity,specificity,positive predict values and negative predict values were 97.2% ,96%,94% and 98.1% respectively for the detection of coronary artery disease(CAD),Further statistical analysis using a 2-related X~2 test showed no obvious difference in the discovery of CAD between 64-slice CTCA and CCA.Comparing both imaging modalities,there was concordance in assessing lesion severity in 311 lesions,and accuracy approaches 86.8%.Conclusions 64-slice CTCA has excellent sensitivity and specificity in detecting CAD,and also can give fairly accurate assessment of stenosis severity in most patients as compared to CCA.As a alternative method it is a useful non-invasive for detecting coronary arteries disease in symptomatic patients

To test the apoptosis inducing effect of hypoxia on cardio myocytes Neonatal Wistar rat cardiomyocaytes were cultured under hypoxic condition for 2 hours,12 hours,24 hours,respectively Flow cytometery,TUNEL and morphological method were used to detect the apoptotic myocytes We found that the number of apoptotic cells of each hypoxia group was greater than that of the control group,and it increased as the time of hypoxia went longer The apoptotic cell number of the control group and the hypoxic groups of 2nd,12th and 24th h. were 9 33?0 62%,17 29?0 95%,33 59?2 09% and 76 01?4 60%( P

The method of acupuncture combined with rehabilitation training in the treatment of shoulder hand syndrome after stroke is reliablet, quick, with simple operation and less adverse reactions. Among them, characteristic acupuncture could focus on the targeted points with obvious effect than ordinary acupuncture, and the combination with rehabilitation training could greatly improve the curative effect. However, there still exist some problems in the current research, such as the difficulty of conducting blind clinical trials of acupuncture therapy; the lack of follow-up data in the evaluation of curative effect, the uncertainty of long-term curative effect; the small sample size of clinical research, etc., so multi-centered and large sample RCT research are still needed.

The current situation of medical information was analyzed by displaying the co-appearance of countries and time, top 5 journals and co-appearance of subject headings in papers on medical information published in 1995-2014 with the papers on medical informatics covered in ISI Web of Science Database as an sample , in order to promote the study and provide reference for the related persons and institutions .

In order to show the development situation and trend in plaque research, Thomson Innovation Platform-covered application of patents associated with plaque researches was quantitatively analyzed using the Thomson Data Analyzer and Thomson Innovation or other tools, which revealed the overall development situation, the main accepted countries, the main application institutions and the technological direction layout of patents associated with plaque researches.

Objective To explore the clinical therapeutic effects in arterial interventional therapy in early osteosarcoma patients.Methods Thirty-eight early osteosarcoma patients received arterial chemoembolization therapies and performed operations.94.7% patients received limb salvage surgeries.Levels of alkaline phosphatase were tested in preoperative and postoperative phases.Results Levels of postoperativealkaline phosphatase[average(191.7±107.0)U/L]were significantly decreased compared with that before interventional therapy[average(1129.1±572.3)U/J.The survival rate in follow-up at 1,3 and 5 years Was97%,79%,50% respectively.The rate of recurrence and metastasis WAg 24%.Conclusions Arterialchemoembolization therapies in patients with early osteosarcoma could improve clinical symptoms effectively,enhance survival rate,relieve recurrence and metastasis,remain affected extremity.The clinical thempeutic effects of iodinated oil were the best among the three embolism materials.

Objective To investigate human papilloma virus(HPV) infection in normal endometrium, atypi-cal hyperplasia of endometrium and endometrial carcinoma. Methods By the nucleic acid hybridization,we detected 28 pairs of endometrial carcinomas, 21 pairs of atypical hyperplasia of endometrium. Normal endometrium from 16 pa-tients with uterine myomas were as control. Results HPV16/18 DNA was detected in 25 endometrial carcinoma and 2 atypical hyperplasia of endometrium and 1 normal endometrium. Conclusions Endometrial carcinoma HPV16/18 DNA were significantly higher than those infected with atypical endometrial hyperplasia and normal endometrium. Note the occurrence of endometrial cancer,the development may be associated with HPV infection.

Objective To evaluate the diagnostic and therapentic value of ERCP for choledocholithiasis.Methods ERCT and EST in 142 cases with suspected choledoholithiasis were performed for treating choledocholithiasis.All the imaging data were analyzed retrospectively.Results Among 142 cases,128 cases were choledocholithiasis,3 cases were suspected choledocholithiasis,6 cases were normal and 5 cases were miss-diagnosis.The diagnostic accuracy of ERCT was 90.1%(128/142).EST were successful in 129 cases,and 4 cases were failure,the successful rate was 96.9%.Conclusion ERCT is of important value in diaguosing choledocholithiasis and EST is safe and reliable for treating choledocholithiasis.

Objective: To explore the clinical significance of combination preoperative carbohydrate loading and postoperative enteral nutrition in patients with gastric cancer during perioperative period. Methods: 70 patients were randomly divided into group A(preoperative fasting + postoperative EN,n = 23),group B(preoperative carbohydrate loading + postoperative TPN,n = 23) and group C(preoperative carbohydrate loading + postoperative EN,n = 20).After operation,insulin sensitivity,nutritional status,immune function and clinical outcome were compared among three groups. Results: Compared with the other two groups in insulin sensitivity,nutritional status,immune function and clinical outcome,the group C was better and different(P

Objective To investigate the effect of lean management on emergency biochemistry test turnaround time(TAT) in clinical laboratories.Methods Based on the approaches of standardized operations,5S on-site management,the efficiency evaluation of batch processing and one piece flow,and visual management,the median time of each workflow,the qualified rate of emergency biochemistry test TAT,the unqualified rate in a relatively concentrated period of TAT timeout and the unqualified rate of collected samples were compared before and after optimization.Results The median times (interquartile ranges) of each workflow including sample receipt and storage,result audit and sample storage-result report before and after lean management were 30 (35) min,7 (13) min,17 (8) min and 16(19) min,5(9) min,16(7) min,respectively,and there were significant differences in the former two(all P ＜0.01) but not the third (P ＞ 0.05).The median times (interquartile ranges) of TAT before and after lean management were 63 (51) min and 46 (33) min,respectively(P ＜ 0.05).The qualified rate of TAT increased from 86.00％ to 95.37％ after lean management(P ＜ 0.01).The unqualified rates in a relatively concentrated period of TAT timeout and collected samples decreased from 3.42％ to 1.00％ (P ＜0.01) and from 0.24％ to 0.17％ (P ＜ 0.01),respectively.Conclusion Lean management may improve process efficiency,reduce errors,and shorten emergency biochemistry test TAT in clinical laboratories.