2.Study Progress on Compound Danshen Drop Pills Resisting Activation and Aggregation of Blood Platelet
Can WU ; Jingying LIU ; Min QI
International Journal of Traditional Chinese Medicine 2009;31(4):380,382-
This article made a summary on the study progress of compound Danshen drop pills resisting activation and aggregation of blood platelet. From the pharmacological point of view, the author explored the possible mechanisms of how compound Danshen drop pills resist the activation and aggregation of blood platelets and drew a conclusion, which is Danshen drop pills exert the function by multiple positions, levels and targets.
3.Clinical Observation of Triptorelin Acetate in the Treatment of Endometriosis after Laparoscopy
Min WU ; Qianrong QI ; Yujie ZOU
China Pharmacy 2016;27(8):1094-1095,1096
OBJECTIVE:To observe clinical efficacy and safety of triptorelin acetate in the treatment of endometriosis after lap-aroscopy. METHODS:196 cases of endometriosis were randomly divided into experimental group and control group with 98 cases in each group according to admission sequence. Both groups received laparoscopic surgery. After surgery,experimental group was given triptorelin acetate by intramuscular injection,3.75 mg/time,every 4 weeks;control group was given gestrinone orally,2.5 mg/time,twice a week,for 5 months. The ovulation,menstrual recovery and the occurrence of ADR were observed in 2 groups. The endometriosis relapse of 2 groups were followed up for 1 year and observed. RESULTS:After treatment,the ovulation recov-ery time and menstrual recovery time of experimental group were all shorter than those of control group,with statistical signifi-cance(P<0.05). The incidence of ADR in experimental group(17.34%)was significantly lower than in control group(35.71%), with statistical significance(P<0.05). During follow-up period,the relapse rate of experimental group(7.14%)was significantly lower than that of control group(18.37%),with statistical significance(P<0.05). CONCLUSIONS:After laparoscopic surgery, triptorelin acetate can significantly improve therapeutic efficacy of endometriosis,reduce the occurrence of ADR.
4.Autologous transplantation of adipose-derived mesenchymal stem cells improves nenal function in diabetic rats
Xiaochun MIN ; Tingting WU ; Shaohua QI ; Weiqi YAO ; Dongcheng WU
The Journal of Practical Medicine 2015;(13):2115-2118
Objective To investigate the renoprotective effects of autologous transplantation of adipose-derived mesenchymal stem cells (ADMSCs) in diabetic rats. Methods Sprague-Dawley (SD) rats were injected intraperitoneally with 40 mg/kg streptozotocin (STZ) for 5 consecutive days to induce type 1 diabetes. Four weeks following STZ injection, eighteen SD rats were randomized into two groups: the diabetic group (n = 9) and the ADMSCs group (n = 9). Normal nondiaetic rats were set as the normal control (n = 9). Autologous ADMSCs were cultured and identified in vitro , which were intravenously injection to the ADMSCs group rats via the tail vein. At 8 weeks after transplantation, levels of blood glucose, insulin, serum urea nitrogen, serumcreatinine and urine protein were measured. Meanwhile the body weight and kidney weight were examined. Results Mesenchymal cell surface markers were expressed in the cultured ADMSCs. The ADMSCs could differentiate into the adipogenic and osteoblastic lineages. Both the diabetic group and the ADMSCs group rats had higher levels of blood glucose , urea nitrogen , serum creatinine , urine protein and higher ratio of the kidney weight/body weight than those in the normal control group (P < 0.05, respectively). Blood glucose, urea nitrogen and the ratio of kidney weight/body weight in the ADMSCs group rats were significantly decreased compared with the diabetic group (P < 0.05, respectively). The decreased insulin level was attenuated after transplantation of ADMSCs (P < 0.05). Besides, levels of serum creatinine and urine protein in the ADMSCs group were lower than those in the diabetic group with no significant difference. Conclusion Autologous transplantation of ADMSCs can improve metabolic disorder and relieves diabetic renal damage.
5.Diagnostic Value on Lung Cancer Screening using Low-dose Spiral CT
Minggang HUANG ; Qing WANG ; Min QI ; Xiaohong WU
Journal of Practical Radiology 2001;0(08):-
Objective To evaluate the possibility and efficiency of early lung cancer screening using low-dose spiral CT,and to investigate the effects of prognosis of lung cancer. Methods 3005 routine chests check-up were carried on the low-dose prospect research of the SHIMADZU 7800 TX spiral CT. According to the result by tracing and long-term CT follow-up based on the baseline screening, biopsy or surgical excisions were recommended in "malignant change" or enlarged nodules. Two doctors separately interpreted all the images blindly.Results 29.9 rate of nodules in all of cases were detected. Smoking group was 1.3 times incidence of non-smoking. A whole incidence of lung cancer was 1.2, including 2.9 in people at high risk of lung cancer and 0.9 in common people. The sensitivity and specificity of lung cancer screening using low-dose spiral CT were 82.9 and 88.8 respectively, and the diagnostic accuracy of lung cancer screening in diameter of nodules less than 10 mm was high than in ones more than 10 mm. Histologically, 33 non-small cell lung cancers (19 stageⅠ, 10 stageⅡand 4 stageⅢ), 2 small cell lung cancers and 1 scar carcinoma were proved based on baseline screening by biopsy or surgery. By the end of 2007, the average survival for clinical stageⅠlung cancer was more than 4 years, clinical stageⅡwas 2~3 years and clinical stageⅢ was 1~2 years. Conclusion Low-dose spiral CT is of high sensitive and specificity in detecting early lung cancer. Preliminary screening study indicates that low-dose spiral CT can greatly improve the likelihood of detection for early lung cancer and situation of survival.
6.Evaluation of posterior pedicle fixation-based dynamic stabilization in treatment of degenerative lumbar disease:recent progress
Xianzhao WEI ; Dajiang WU ; Min QI ; Ming LI
Academic Journal of Second Military Medical University 2000;0(07):-
Posterior pedicle fixation-based dynamic stabilization is now densely studied in the non-fusion spine surgery.The method is characterized by the motion preservation of segmental lumbar,avoidance of the stress change after fusion surgery,and adjacent disc degeneration.Posterior pedicle fixation-based dynamic stabilization systems have undergone fast development and are now used for the treatment of degenerative lumbar spine disease.As an innovation of traditional fusion surgery,the clinical evaluation of its efficacy has become a focus of study among spine surgeons.In this paper,we review the recent progress in the clinical efficacy of posterior pedicle fixation-based dynamic stabilization.
7.Risk factors and prognosis for 894 cases of esophageal neoplasm patients with preoperative nutritional risk
Min TANG ; Qi PAN ; Junwei WU ; Xigui TIAN ; Desen LIU
Chinese Journal of Thoracic and Cardiovascular Surgery 2015;31(7):385-387
Objective To provide the reference basis for reducing the occurrence of nutritional risk by analyzing possible risk factors for nutritional risk status and investigating the relationship between preoperative nutritional risk status and prognosis.Methods We retrospectively analyzed the clinical data of 894 patients(nutritional risk group of 491 cases,non-nutritional risk group of 403 cases) with esophageal cancer resection.The univariate analysis was used to analyze the relationships between nutritional risk status with postoperative complications and length of hospitalization.And the multiple Logistic regression model analysis was applied to analyze the risk factors of nutritional risk status.Results The nutritional risk group had a higher rate of postoperative complications (33.60 % vs.19.60 %,U =-3.429,P =0.001),higher incidence of serious complications (23.01% vs.8.68%,U =-3.611,P =0.000) and longer hospital stays [(37.20 ± 13.89) days vs.(31.69 ± 13.49) days,t =4.124,P =0.000] than that of non-nutritional risk group.The results of the multiple logistic regression analysis showed that the preoperative nutritional risk factors were associated with the patients' age (OR =1.58,95% CI:1.101-2.268),number of symptoms entries(OR =7.97,95 % CI:6.071-10.463),symptom severity (OR =0.26,95% CI:0.186 -0.385),and dietary intake (OR =0.62,95 % CI:0.482-0.813),P < 0.05 for all.Conclusion The older patients with more severe symptoms and poor diet are more likely to suffer from nutritional risk.Prolonged hospital stay and postoperative complications easily happen in patients with nutritional risk.So patients with preoperative nutritional risk should be given timely and effective nutrition intervention measures,in order to reduce postoperative complications and length of hospitalization.
8.Principle and clinical application of ultrasonic surgical installation
Min WU ; Liming TANG ; Tiebing LIU ; Shitao QI ; Jie SHAO
Chinese Medical Equipment Journal 2003;0(10):-
With the appearance and development of ultrasonic surgical installation, ultrasonic therapy enters on a new epoch. High-amplitude and high-power ultrasonic vibration produced during the operation, ultrasonic surgical installation can be used to decrease the amount of bleeding or stop bleeding according to the acoustic properties of different tissues. The part where pathological changes happen can be excised selectively by ultrasonic surgical installation. This article introduces the principle, structure, classification and clinical application of ultrasonic surgical installation in detail.
9.Method for assessing bid of medical equipment based on BP neural network
Shitao QI ; Liming TANG ; Min WU ; Tiebing LIU
Chinese Medical Equipment Journal 2003;0(10):-
This paper introduces the basic theory of BP neural network and develops a model for assessing bid of medical equipment based on BP neural network. A case is analyzed with the model, and the result shows the high accuracy of it.
10.The development of virtual ECG sampling system
Shitao QI ; Liming TANG ; Min WU ; Tiebing LIU ; Haifeng CHEN
Chinese Medical Equipment Journal 1989;0(03):-
This paper introduces a virtual ECG sampling system based on LabVIEW. The system, utilizing self-developed ECG sampling card, fulfils ECG measurement and A/D conversion safely and realizes ECG data processing and display under Labview developing environment.