1.A Case of Complex Partial Status Epilepticus.
Journal of the Korean Child Neurology Society 1999;7(1):107-112
Nonconvulsive status epilepticus, which constitutes about 25% of all cases of status, has been subdivided into generalized nonconvulsive(absence) status and complex partial status. We report a case of complex partial status epilepticus in a 3-year-old male patient with altered mental function lasting about 24 hours. The electroencephalographic finding was compatible with complex partial status and the outcome of treatment is excellent, so far.
Child, Preschool
;
Humans
;
Male
;
Status Epilepticus*
2.MRI follow-up study and 1H-MR spectroscopic finding in a patient with Kearns-Sayre syndrome.
Chulhee CHOI ; Il Nam SUNWOO ; Tae Seung KIM ; Pyoung JEON
Journal of the Korean Neurological Association 1998;16(3):388-391
Serial Brain MRI was performed on a seventeen-year-old girl with Kearns-Sayre syndrome. At the age of 11, she complained bilateral ptosis. Two years later, bilateral blepharoplasty was done and brain MRI was taken. T2-weighted MRI sequence showed high signal intensity areas in the brainstem, thalamus and white matter of the cerebrum and cerebellum bilaterally. Four years later, chronic progressive external ophthalmoplegia developed and serial MRI and proton MRS were taken. Follow-up MRI showed similar but slightly progressed findings compared with previous films. The proton MR spectroscopic imaging demonstrated focal localization of abnormally increased lactate content in the involved area of the brain.
Blepharoplasty
;
Brain
;
Brain Stem
;
Cerebellum
;
Cerebrum
;
Female
;
Follow-Up Studies*
;
Humans
;
Kearns-Sayre Syndrome*
;
Lactic Acid
;
Magnetic Resonance Imaging*
;
Magnetic Resonance Spectroscopy
;
Ophthalmoplegia, Chronic Progressive External
;
Protons
;
Thalamus
3.Carotid Stump as a Cause of Recurrent Embolism-Endovascular Treatment in a Case of Congenital Carotid Stump Syndrome.
Jonghwa SHIN ; Jihoon CHA ; Pyoung JEON ; Oh Young BANG
Journal of Stroke 2015;17(3):359-361
No abstract available.
4.Genetic Analysis in a Case of Transient Neonatal Diabetes Mellitus with Congenital Adrenal Hyperplasia.
Hye Jin KWON ; Jin A PARK ; Sang Lack LEE ; Heung Sik KIM ; Dong Seok JEON ; Dong Kyu JIN ; Pyoung Han HWANG
Journal of Korean Society of Pediatric Endocrinology 2002;7(1):116-121
A case of transient neonatal diabetes mellitus combined with congenital adrenal hyperplasia(CAH) is described. A female infant was born by cesarean delivery due to fetal distress, she had sunken eyeball and anterior fontanelle, large protruded tongue and thin subcutaneous tissues. She had large clitoris and progressive pigmentation on whole body was observed since 10th day of birth. Hyperglycemia and glycosuria was noted at 3rd day of birth. Level of insulin and C-peptide was 3.0 mU/L and 0.35 ng/mL respectively. Serum ACTH was 870.4 pg/mL and 17-hydroxyprogesterone was increased to 20,000 ng/dL. Serum Na was 124 mEq/L, K 5.6 mEq/L. Abdominal MRI showed no abnormality. Chromosomal study showed 46,XX. Genetic analysis with polymorphic DNA markers for chromosome 6 showed paternal uniparental isodisomy at D6S276, D6S1704 and DNA analysis of CYP 21 gene showed mutation at P435S. She required insulin therapy for 8 months after birth. Hydrocortisone and florinef was needed for the control of CAH.
17-alpha-Hydroxyprogesterone
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Adrenal Hyperplasia, Congenital*
;
Adrenocorticotropic Hormone
;
C-Peptide
;
Chromosomes, Human, Pair 6
;
Clitoris
;
Cranial Fontanelles
;
Diabetes Mellitus*
;
DNA
;
Female
;
Fetal Distress
;
Genetic Markers
;
Glycosuria
;
Humans
;
Hydrocortisone
;
Hyperglycemia
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Infant
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Insulin
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Magnetic Resonance Imaging
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Parturition
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Pigmentation
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Subcutaneous Tissue
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Tongue
;
Uniparental Disomy
5.High-dose Methylprednisolone Pulse Therapy in Measles Postinfectious Encephalomyelitis: Two Cases of Successful Recovery.
Me Jin KIM ; Hee Jung CHUNG ; Pyoung JEON
Journal of the Korean Child Neurology Society 2002;10(1):142-149
We treated two patients of measles postinfectious encephalomyelitis with intravenous methylprednisolone pulse therapy(1 g/1.73 m2/day for 5 days) 38 hours and 5 days respectively after the onset of neurologic symptoms. Despite extensive white matter involvement shown in MRI and severe clinical symptoms, the patients recovered from their neurologic symptoms dramatically following intravenous methylprednisolone pulse therapy. Because acute postinfectious encephalomyelitis has been postulated to be immunologically mediated disease, instead of direct viral invasion, ACTH and dexamethasone are widely used and the outcome is variable. This case report of successful recovery from fulminant ADEM with pulse intravenous methylprednisolone therapy, although uncontrolled, suggests that this therapeutic regimen should be studied in other cases.
Adrenocorticotropic Hormone
;
Dexamethasone
;
Encephalomyelitis, Acute Disseminated*
;
Humans
;
Magnetic Resonance Imaging
;
Measles*
;
Methylprednisolone*
;
Neurologic Manifestations
6.Stenting of Symptomatic Middle Cerebral Artery Stenosis: Case Report.
Pyoung JEON ; Yong Sam SHIN ; Sung Ryoung LIM ; Sun Jung KIM
Korean Journal of Cerebrovascular Disease 2002;4(2):155-158
Percutaneous balloon angioplasty has been reported to be useful in the treatment of intracranial atherosclerotic arterial stenosis. However, arterial dissection with increased risk of acute closure and stroke has limited its widespread implementation. Stenting of the intracranial vasculature recently has been shown to be feasible in a variety of circumstance. However, stenting of middle cerebral artery has been limited because of difficulty with tracking stents across the carotid siphon. We report a case of successful percutaneous stenting of a symptomatic middle cerebral artery stenosis using a balloon-expandible flexible coronary stent.
Angioplasty
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Angioplasty, Balloon
;
Constriction, Pathologic*
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Middle Cerebral Artery*
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Stents*
;
Stroke
7.Rescue Balloon Reposition of the Protruding Coil Loops during Endovascular Treatment of An Anterior Communicating Artery Aneurysm: A Case Report.
Hong Gee ROH ; Hyun Seung KANG ; Pyoung JEON ; Hong Sik BYUN
Neurointervention 2006;1(1):68-72
Protrusion of coil loop(s) and subsequent occlusion of the parent artery is one of the dreadful complications during endovascular coil embolization of cerebral aneurysm. Although protrusion of one or two coil loops may not cause adverse events and can be ignored in many instances, it can also compromise the parent artery in some cases with or without thrombus formation. We report a case of rescue balloon reposition of the protruding coil mass back into the aneurysm and recanalization of parent artery during embolization of the anterior communicating artery aneurysm.
Aneurysm
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Arteries
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Embolization, Therapeutic
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Humans
;
Intracranial Aneurysm*
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Parents
;
Thrombosis
8.Prevalence of Unruptured Intracranial Aneurysm on MR Angiography.
Tae Yeon JEON ; Pyoung JEON ; Keon Ha KIM
Korean Journal of Radiology 2011;12(5):547-553
OBJECTIVE: To evaluate the prevalence of incidentally found unruptured intracranial aneurysms (UIAs) on the brain MR angiography (MRA) from a community-based general hospital. MATERIALS AND METHODS: This was a prospectively collected retrospective study, carried out from January 2004 to December 2004. The subjects included 3049 persons from a community-based hospital in whom MRA was performed according to a standardized protocol in an outpatient setting. Age- and sex-specific prevalence of UIAs was calculated. The results by MRA were compared with intra-arterial digital subtraction angiography (DSA) findings. RESULTS: Unruptured intracranial aneurysms were found in 137 (5%) of the 3049 patients (M:F = 43:94; mean age, 60.2 years). The prevalence of UIAs was 5% (n = 94) in women and 4% (n = 43) in men, respectively (p = 0.2046) and showed no age-related increase. The most common site of aneurysm was at the distal internal carotid artery (n = 64, 39%), followed by the middle cerebral artery (n = 40, 24%). In total, 99% of aneurysms measured less than 12 mm, and 93% of aneurysms measured less than 7 mm. Direct comparisons between MRA and DSA were available in 70 patients with 83 UIAs; the results revealed two false positive and two false negative results. CONCLUSION: This community-hospital based study suggested a higher prevalence of UIAs observed by MRA than previously reported. These findings should be anticipated in the design and use of neuroimaging in clinical practice.
Adolescent
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Adult
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Aged
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Aged, 80 and over
;
Aneurysm, Ruptured/diagnosis
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Angiography, Digital Subtraction
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Cerebral Angiography
;
Female
;
Humans
;
Incidental Findings
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Intracranial Aneurysm/*diagnosis/radiography
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*Magnetic Resonance Angiography
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Male
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Middle Aged
;
Young Adult
9.Perirolandic Hypoperfusion on Tc-99m ECD Brain SPECT in Term Infants with Perinatal Asphyxia: Comparison with MRI and Clinical Findings.
Sun Ah LEE ; Young Hoon RYU ; Jong Doo LEE ; Yoon Joon HWANG ; Dong Ik KIM ; Pyeong Ho YOON ; Pyoung JEON ; Sung Wook MOON ; Chang Il PARK
Korean Journal of Nuclear Medicine 1997;31(1):1-8
No abstract available.
Asphyxia*
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Brain*
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Humans
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Infant*
;
Magnetic Resonance Imaging*
;
Tomography, Emission-Computed, Single-Photon*
10.The Effect of Paroxetine in Chronic Schizophrenic Inpatients with Depressive Symptoms: A Double-Blind Placebo-Controlled Study.
Pyoung Ju HAN ; Young Suk PAIK ; Sang Woo OH ; Hyun Tae JEON ; Ji Young KIM
Journal of Korean Neuropsychiatric Association 2000;39(4):774-786
OBJECTIVES: This double-blind placebo-controlled study was conducted to demonstrate the improvement of depressive, positive and negative symptoms, and general psychopatholgy in depressed chronic schizophrenic inpatients with adjunctive paroxetine 20mg therapy in the morning. METHODS: Forty nine chronic schizophrenic inpatients with depressive symptoms were randomly received adjunctive paroxetine or placebo for 6 week study period. Therapeutic effect and side effects were evaluated by means of the Hamilton Rating Scale for Depression (HRSD), the Brief Psychiatric Rating Scale (BPRS), the Positive and Negative Syndrome Scale (PANSS), the Extrapyramidal Symptom Rating Scale (ESRS), the UKU side effect rating scale (UKU), and the Clinical Global Impression (CGI) at baseline, first, second, forth, and sixth week of treatment in a controlled double-blind design. RESULTS: 18 patients completed six weeks of paroxetine therapy, and 18 patients placebo therapy. 1) Comparison between paroxetine and placebo groups: (1) HRSD total scores in both groups were significantly decreased (p< 01) but there was no statistically significant difference between 2 groups. This study showed that significant effect in paroxetine group appeared at 2nd week of treatment (p< 01), while in placebo group at 4th week of treatment (p< 01). (2) PANSS, BPRS, CGI, ESRS, and UKU: In both groups, PANSS total scores and CGI scores were significantly decreased respectively (p< 01, p< 05) and thus indicated the improvement of global psychopathology and entire effects. There were no significant differences between 2 groups in positive, negative symptoms, general psychopathology, and drug side effects. 2) Comparison between responding and nonresponding groups in paroxetine adjunctive therapy: (1) Compared with nonresponding group, responding group had significant decrease in HRSD total score (p< 01), in HRSD subitems such as depressed mood, suicide, psychic anxiety, and feelings of guilt (p< 01), and in other subitems such as work and activity, early insomnia, and hypochondriasis (p< 05). (2) Compared with nonresponding group, responding group had significantly decrease in BPRS total score (p< 01) and in general subscale of PANSS (p< 05). CONCLUSION: The results suggest that both paroxetine and placebo groups were improved in depressive symptoms, but paroxetine group had more rapid improvement than placebo group. There were no significant differences in positive symptoms, negative symptoms, general psychopathology, and drug side effects between two groups. Compared with nonresponding group in paroxetine adjunctive therapy, responding group had significant improvement in depressive symptoms and general psychopathology.
Anxiety
;
Brief Psychiatric Rating Scale
;
Depression*
;
Guilt
;
Humans
;
Hypochondriasis
;
Inpatients*
;
Paroxetine*
;
Psychopathology
;
Schizophrenia
;
Sleep Initiation and Maintenance Disorders
;
Suicide