No abstract available.
Pyoderma Gangrenosum*

Summary Pyoderma gangrenosum (PG) of the breast is a rare rapidly progressive neutrophilic dermatosis, which usually co-exists with severe underlying systemic conditions. A woman presented with a non-healing ulcer over her right breast with characteristic sparing of nipple-areola complex (Bork-Baykal phenomenon). It was diagnosed as pyoderma gangrenosum on the basis of clinico-pathological correlation and managed successfully with systemic corticosteroids and anti-inflammatory drugs along with wound care. The diagnosis and treatment of PG is challenging particularly at unusual sites given the paucity of robust clinical evidence and lack of consensus opinion regarding specific management guidelines. It is imperative that PG is considered as a clinical diagnosis in any patient with enlarging, sterile, necrotic lesions unresponsive to appropriate antibiotics. Early recognition of PG at rare locations can prevent devastating sequelae such as over-zealous surgical debridement and deep tissue infections associated with a chronic open wound leading to severe cosmetic morbidity.
Pyoderma Gangrenosum

Introduction: Superficial granulomatous pyoderma is a rare superficial variant of pyoderma gangrenosum. With clinical and histological features that mimic infectious processes, misdiagnosis is common. This report aims to present a rare, often overlooked disease, highlighting the need for timely histopathologic diagnosis to prevent unnecessary treatment and morbidity. Case: Patient is a 42-year-old female with recurrent painful ulcers on her right leg. Initial histopathology was interpreted as granulomatous dermatitis secondary to cutaneous tuberculosis and was managed with anti-Koch’s regimen for six months. However, the ulcers worsened, which led to right leg amputation. New similar ulcers eventually recurred over the other extremities where repeat biopsy have shown neutrophilic dermatosis with a three-layer granuloma that is distinctive for superficial granulomatous pyoderma. Patient was treated with oral corticosteroids which was effective in controlling the disease. Conclusion This report documents a rare case of superficial granulomatous pyoderma presenting as non-healing ulcer, previously misdiagnosed and treated with unwarranted surgery and anti-microbials. The awareness of the characteristic clinical and histopathological features is essential for diagnosis so as to provide rapid disease control and avoid potentially aggravating management.
Pyoderma Gangrenosum ;

No abstract available.
Pyoderma ; Pyoderma Gangrenosum

Pyoderma gangrenosum occuring in Behcet's disease have been rarely reported, but there are several clinical and histological similarities between Behcet's disease and pyoderma gangrenosum. We report the case of pyoderma gangrenosum occuring in Behcet's disease and describe the similarities of these diseases.
Pyoderma Gangrenosum* ; Pyoderma*

No abstract available.
Pyoderma ; Pyoderma Gangrenosum

No abstract available.
Pyoderma Gangrenosum* ; Pyoderma* ; Ulcer*

A variety of cutaneous lesions have been described in Behcet's disease including erythema nodosum-like lesion, pseudofolliculitis, papulopustular eruption, subcutaneous thrombophlebitis, erythema multiforme-like lesion and pyoderma gangrenosum, etc. Pyoderma gangrenosum has rarely been reported in association with Behcet's disease. However, there is an extensive clinical and histological overlap between Behcet's disease and pyoderma gangrenosum. We report a case of Behcet's disease associated with pyoderma gangrenosuma.
Erythema ; Pyoderma Gangrenosum* ; Pyoderma* ; Thrombophlebitis

No abstract available.
Myelodysplastic Syndromes* ; Pyoderma Gangrenosum* ; Pyoderma*

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis, closely associated with the immune system. Its pathogenesis is currently not clear. The lack of specificity in the clinical manifestations and histopathological changes of PG leads to a long clinical diagnosis cycle and even misdiagnosis, which is easy to delay treatment or promote the deterioration of ulcer wound. The diagnosis of this disease is still very difficult, which poses a great challenge to wound repair practitioners. This article reviews the research advances on the pathophysiology, clinical features, and diagnosis of PG in recent years, with the aim of providing reference for relevant clinical practitioners.
Humans ; Pyoderma Gangrenosum/pathology*