Blood gas parameters were measured in 20 patients with chronic cor pulmonale before and after a course of hyperbaric oxygenation therapy (HBO). Results found that the HBO has increased PaO2 of patients from 73.8mmHg to 81.1mmHg and reduced AsDO2 from 26.5mmHg to 19.9mmHg with p<0.05. Except parameters of PaO2, pH and PaCO2, other parameters such as AaDO2, PaO2 and P50 must be measured in order to evaluate completely the effect of HBO. (Auth)
Pulmonary Heart Disease ; therapeutics

No abstract available.
Pulmonary Disease, Chronic Obstructive* ; Pulmonary Heart Disease* ; Tuberculosis, Pulmonary*

Cor pulmonale is defined as alteration in structure and function of the right ventricle of the heart caused by a primary disorder of the lungs. Presented are two cases of gravidocardiac patients from cor pulmonale secondary to multi-drug resistant tuberculosis. The first case is a case of a 37-year-old gravida 4 para 3 (3-0-0-3) and the second case is that of a 24-year-old pimigravid, both of which were on their third trimester with no known cardiac disease, both initially presenting with dyspnea and heart failure symptoms. The first patient was not in labor, managed conservatively and was discharged clinically improved; the latter was delivered abdominally who later succumbed to fatal arrhythmia. Presented are the strategies in management and challenges encountered in managing a pregnant cardiac patient from cor pulmonale, specifically from pulmonary tuberculosis.
Pulmonary Heart Disease ; Hypertension, Pulmonary ; Pulmonary Artery ; Heart Diseases ; Tuberculosis ; Tuberculosis, Pulmonary ; Pregnancy Complications

Chronic obstructive pulmonary disease (COPD) is one of the causes of cor pulmonale. Cor pulmonale patients with pulmonary hypertension have a significant lower survival rate than patients without. However, there is no conclusive treatment options in cor pulmonale and pulmonary hypertension associated with COPD until now. We report a patient with cor pulmonale and pulmonary hypertension associated with severe form of COPD and tuberculous destroyed lung who achieved marked clinical, functional and echocardiographic hemodynamic improvements with inhaled iloprost for six months.
Echocardiography ; Hemodynamics ; Humans ; Hypertension, Pulmonary* ; Iloprost* ; Lung* ; Pulmonary Disease, Chronic Obstructive ; Pulmonary Heart Disease* ; Survival Rate

Chronic obstructive pulmonary disease (COPD) is a chronic progressive disease, characterized by irreversible airflow limitation, with a partially reversible component. The pathological abnormalities of COPD are associated with lung inflammation, imbalances of proteinase and antiproteinase, and oxidative stress, which are induced by noxious particles and gases in susceptible individuals. The physiological changes of COPD are mucus hyper-secretion, ciliary dysfunction, airflow limitation, pulmonary hyperinflation, gas exchange abnormalities, pulmonary hypertension, cor pulmonale and systemic effects. The airflow limitation principally results from an increase in the resistance of the small conducting airways and a decrease in pulmonary elastic recoil due to emphysematous lung destruction. This article provides a general overview of the pathophysiology of COPD.
Emphysema ; Gases ; Hypertension, Pulmonary ; Lung ; Mucus ; Oxidative Stress ; Pneumonia ; Pulmonary Disease, Chronic Obstructive* ; Pulmonary Heart Disease

No abstract available.
Breast Neoplasms* ; Breast* ; Humans ; Pulmonary Heart Disease* ; Thrombotic Microangiopathies*

Electrocardiographic sign was studied for the evaluation of the state of Corpulmonale in coal workers' pneumoconiosis who were admitted and dead as complication of CWP in Don-ghae hospital, Fourty-eight cases were gatherpd. The prevalence rate of right axis deviation was 28.3%. p-pulmonale in lead II was 30.4%, R/S< or =1 in V5 was 23.9. But che pulmonary artereal pressure can be increased without the change of ECG. so the elortrocardiugraphical sign should be treated as reference data.
Axis ; Coal* ; Electrocardiography* ; Pneumoconiosis* ; Prevalence ; Pulmonary Heart Disease*

Adolescent ; Female ; Humans ; Infant ; Male ; Pulmonary Heart Disease ; diagnosis ; therapy

Chronic pulmonary artery thromboembolism is a relatively rare phenomenon causing hypoxia and pulmonary hypertension that eventually leads to respiratory failure and right heart failure. Patients with acute pulmonary artery thromboembolism are generally treated with antithrombotics and thrombolytics. However, in cases with chronic pulmonary artery thromboembolism the fibrinized thrombus is so strongly adhered to the pulmonary artery wall that medical treatment becomes ineffective and surgical treatment must then be considered. We report a 47year old patient, with a history of repeated admission due to unresolved chronic obstructive pulmonary disease and chronic pulmonary artery thromboembolism at a local hospital, who underwent a successful endarterectomy of pulmonary artery thromboemboli using intermittent total circulatory arrest.
Anoxia ; Endarterectomy* ; Fibrin ; Heart Failure ; Humans ; Hypertension, Pulmonary ; Pulmonary Artery ; Pulmonary Disease, Chronic Obstructive ; Pulmonary Embolism* ; Respiratory Insufficiency ; Thromboembolism ; Thrombosis

Chronic obstructive pulmonary disease (COPD) is a chronic progressive disease that is characterized by irreversible airflow limitation with a partially reversible component. The pathologic abnormalities of COPD are associated with lung inflammation, an imbalance of proteinases and antiproteinases, and oxidative stress that are induced by noxious particles and gases in susceptible individuals. The physiologic changes of COPD are mucus hypersecretion, ciliary dysfunction, airflow limitation, pulmonary hyperinflation, gas exchange abnormalities, pulmonary hypertension, cor pulmonale, and systemic effects. The airflow limitation results principally from an increase in the resistance of the small conducting airways and a decrease in the pulmonary elastic recoil due to emphysematous lung destruction. This article provides a general overview of the pathophysiology of COPD.
Emphysema ; Gases ; Hypertension, Pulmonary ; Lung ; Mucus ; Oxidative Stress ; Peptide Hydrolases ; Pneumonia ; Pulmonary Disease, Chronic Obstructive* ; Pulmonary Heart Disease