1.Prediction on the burden of disease of chronic obstructive pulmonary disease and simulation of the effectiveness of controlling risk factors in China by 2030.
Ruo Tong LI ; Zhen Zhen RAO ; Yan Hong FU ; Ting Ling XU ; Jiang Mei LIU ; Shi Cheng YU ; Mai Geng ZHOU ; Wen Lan DONG ; Guo Qing HU
Chinese Journal of Epidemiology 2022;43(2):201-206
Objective: To forecast the burden of chronic obstructive pulmonary disease (COPD) in China by 2030 and evaluate the effectiveness of controlling risk factors based on the predictive model. Methods: Based on the relationship between the death of COPD and exposure to risk factors and the theory of comparative risk assessment, we used the estimates of the Global Burden of Disease Study 2015 (GBD2015) for China, targets for controlling risk factors, and proportion change model to project the number of deaths, standardized mortality rate, and probability of premature mortality from chronic respiratory diseases by 2030 in different scenarios and to evaluate the impact of controlling the included risk factors to the disease burden of COPD in 2030. Results: If the trends in exposure to risk factors from 1990 to 2015 continued, the number of deaths and the mortality for COPD would be 1.06 million and 73.85 per 100 000 population in China by 2030, respectively, with an increase of 15.81% and 10.69% compared to those in 2015. Compared to 2015, the age-standardized mortality rate would decrease by 38.88%, and the premature mortality would reduce by 52.73% by 2030. If the smoking rate and fine particulate matter (PM2.5) concentration separately achieve their control targets by 2030, there would be 0.34 and 0.27 million deaths that could be avoided compared to the predicted numbers based on the natural trends in exposure to risk factors and the probability of premature death would reduce to 0.59% and 0.52%, respectively. If the control targets of all included risk factors were achieved by 2030, a total of 0.53 million deaths would be averted, and the probability of premature death would decrease to 0.44%. Conclusions: If the exposures to risk factors continued as showed from 1990 to 2015, the number of deaths and mortality for COPD would increase by 2030 compared to 2015, and the standardized mortality and the probability of premature death would decrease significantly, which would achieve the targets of preventing and controlling COPD. If the exposure to the included risk factors all achieved the targets by 2030, the burden of COPD would be reduced, suggesting that the control of tobacco use and air pollution should be enhanced to prevent and control COPD.
Air Pollutants/analysis*
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Air Pollution/prevention & control*
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China/epidemiology*
;
Cost of Illness
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Environmental Exposure
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Humans
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Particulate Matter/analysis*
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Pulmonary Disease, Chronic Obstructive/prevention & control*
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Risk Factors
2.Progress in research of influenza vaccine and 23 valent pneumococcal polysaccharide vaccine immunization in patients with chronic obstructive pulmonary disease.
Hai Tian SUI ; Yu GUO ; Zhong Nan YANG ; Jin Feng SU ; Xiang SHU ; Yang ZHANG ; Hua Qing WANG ; Xiaoming YANG
Chinese Journal of Epidemiology 2022;43(9):1508-1512
A comprehensive review of the research of the effectiveness of influenza vaccine and 23 valent pneumococcal polysaccharide vaccine (PPV23) in patients with chronic obstructive pulmonary disease (COPD) both at home and abroad in recent years showed that influenza vaccine and PPV23 immunization can significantly reduce the risk for influenza and pneumonia in COPD patients, and reduce the acute exacerbation of disease and related hospitalization. In particular, the influenza vaccination can also reduce the risk for ischemic heart disease, acute coronary syndrome, ventricular arrhythmia, lung cancer, dementia and death in the patients, and the immunization of both vaccines has a more significant protective effect. It is recommended by authoritative guidelines both at home and abroad that COPD patients can receive influenza vaccine and PPV23. At present, the coverage of domestic influenza and pneumococcal vaccines are low, and there are less studies in the applications of both vaccines in patients with COPD. Effective measures should be taken to strengthen the health education and increase the vaccination coverage. Additionally, the clinical research of influenza vaccine and PPV23 for COPD patients, especially the analysis on clinical benefit of immunization of both vaccines, should be further strengthened to effectively improve the survival and prognosis of COPD patients.
Humans
;
Influenza Vaccines/therapeutic use*
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Influenza, Human/prevention & control*
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Pneumococcal Vaccines
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Pulmonary Disease, Chronic Obstructive
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Vaccination
4.Importance for surveillance on chronic obstructive pulmonary disease among Chinese adults.
Chinese Journal of Epidemiology 2018;39(5):541-545
The first national surveillance of COPD in mainland China was carried out in 2014, with the nationally representative data obtained. The national surveillance was significantly important for the monitoring of prevalence, risk factors, and changing trend of COPD among Chinese adults aged ≥ 40. The surveillance was also important in the development of national COPD prevention and control policy, the evaluation of prevention and control progress, the establishment of COPD comprehensive surveillance system, and the building of a professional COPD monitoring and prevention team. In this editorial, we briefly introduced the method and content of COPD surveillance, and reported the rate of spirometry examination and COPD awareness among adults aged ≥40 in China. We also analyzed the rate of main risk factors for COPD, such as tobacco smoking, occupational exposure to dust or chemical and indoor exposure to biomass or coal, and the distribution of high-risk population. This study provided fundamental data for the prevention and control of COPD in China.
Adult
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Aged
;
Air Pollution, Indoor/statistics & numerical data*
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China/epidemiology*
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Chronic Disease/epidemiology*
;
Dust
;
Female
;
Humans
;
Male
;
Occupational Exposure/statistics & numerical data*
;
Population Surveillance/methods*
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Prevalence
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Pulmonary Disease, Chronic Obstructive/prevention & control*
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Risk Factors
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Smoking
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Spirometry
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Tobacco Smoke Pollution/statistics & numerical data*
5.Effect of influenza and 23-valent pneumococcal polysaccharide vaccinations on elderly with chronic obstructive pulmonary diseases: a community-based intervention study.
Y WEN ; L HE ; Y ZHAI ; J WU ; Y Y CHEN ; H WANG ; Q Q ZONG ; X F LIANG
Chinese Journal of Epidemiology 2018;39(6):792-798
Objective: To explore the effect of influenza and 23 valent pneumococcal polysaccharide pneumococcal vaccinations on symptom-improvement among elderly with chronic obstructive pulmonary diseases (COPD). Methods: Data was gathered from 4 communities in 3 National Demonstration Areas set for comprehensive prevention and control of chronic non- communicable diseases in Chongqing city and Ningbo city respectively, from November 2013 to October 2014. The communities were selected by cluster sampling and divided into 4 groups: (1) injected influenza vaccines; (2) injected with pneumococcal vaccines; (3) received both of the two vaccines; (4) the control group that without any intervention measures. All the subjects aged from 60 to 75 were selected to fill in demographic information questionnaire and receive (COPD assessment test, CAT) scores twice, before intervention and 1 year after the vaccination. SAS 9.4 software was used to analyze the change of symptoms and CAT scores before and after the intervention program and comparing the improvement on symptoms among the elderly people under study. Results: A total of 1 244 subjects with nearly same baseline conditions after the propensity score matching, were involved in this study. CAT scores appeared as Median=21 (IQR: 17-26) at baseline. The CAT scores appeared as Median=18 (IQR: 14-24), decreasing in all the 3 vaccinated groups, one year after the intervention program (influenza vaccines, matching t test, t=-6.531, P=0.403; pneumococcal vaccines, Wilcoxon test, H=-9 623, P<0.001; combined vaccine vaccines, matching t test, t=-10.803, P<0.001). However, in the control group, no obvious change was observed (Wilcoxon H=1 167, P=0.403). Proportions of impacts at high or very high levels all decreased in the 3 intervention groups, while little change was observed in the control group. Outcomes from the Factorial analysis suggested that influenza vaccination could improve the general conditions and symptoms including cough, chest tightness, dyspnea, physical activities, and stamina. Pneumococcal vaccination appeared more effective on all of symptoms and indicators. Conclusion: Pneumococcal and influenza vaccination seemed helpful for elderly people suffering COPD to improve the general health condition.
Aged
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Humans
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Influenza Vaccines/immunology*
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Influenza, Human
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Pneumococcal Vaccines/immunology*
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Pneumonia, Pneumococcal/prevention & control*
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Pulmonary Disease, Chronic Obstructive/complications*
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Streptococcus pneumoniae
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Surveys and Questionnaires
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Vaccination/statistics & numerical data*
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Vaccine Potency
6.Influenza Vaccination Coverage Rate according to the Pulmonary Function of Korean Adults Aged 40 Years and Over: Analysis of the Fifth Korean National Health and Nutrition Examination Survey.
Seung Hyun CHA ; Jeong Hun PAIK ; Mi Ra LEE ; Huiho YANG ; Seung Guk PARK ; Young Jee JEON ; Sunmi YOO
Journal of Korean Medical Science 2016;31(5):709-714
Influenza vaccination is an effective strategy to reduce morbidity and mortality, particularly for those who have decreased lung functions. This study was to identify the factors that affect vaccination coverage according to the results of pulmonary function tests depending on the age. In this cross-sectional study, data were obtained from 3,224 adults over the age of 40 who participated in the fifth National Health and Nutrition Examination Survey and underwent pulmonary function testing in 2012. To identify the factors that affect vaccination rate, logistic regression analysis was conducted after dividing the subjects into two groups based on the age of 65. Influenza vaccination coverage of the entire subjects was 45.2%, and 76.8% for those aged 65 and over. The group with abnormal pulmonary function had a higher vaccination rate than the normal group, but any pulmonary dysfunction or history of COPD did not affect the vaccination coverage in the multivariate analysis. The subjects who were 40-64 years-old had higher vaccination coverage when they were less educated or with restricted activity level, received health screenings, and had chronic diseases. Those aged 65 and over had significantly higher vaccination coverage only when they received regular health screenings. Any pulmonary dysfunction or having COPD showed no significant correlation with the vaccination coverage in the Korean adult population.
Adult
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Aged
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Asian Continental Ancestry Group
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Cross-Sectional Studies
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Female
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Humans
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Influenza Vaccines/*immunology
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Influenza, Human/*prevention & control
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Logistic Models
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Male
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Middle Aged
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Nutrition Surveys
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Odds Ratio
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Pulmonary Disease, Chronic Obstructive/diagnosis
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Republic of Korea
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Respiratory Function Tests
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Vaccination/*statistics & numerical data
7.Awareness of COPD in a High Risk Korean Population.
Jae Yong SEO ; Yong Il HWANG ; So Yeong MUN ; Jin Hee KIM ; Joo Hee KIM ; Sung Hoon PARK ; Seung Hun JANG ; Yong Bum PARK ; Jae Jung SHIM ; Ki Suck JUNG
Yonsei Medical Journal 2015;56(2):362-367
PURPOSE: Increased awareness and understanding of chronic obstructive pulmonary disease (COPD) is an important aspect of disease management. The aim of this study was to explore COPD awareness among smokers participating in a smoking cessation program. MATERIALS AND METHODS: Face-to-face interviews were conducted with 289 subjects in three smoking cessation clinics, using a structured questionnaire. RESULTS: A total of 68.2% of subjects had COPD-related symptoms, and 19.7% were in poor health. Only 1.0% of the subjects knew that COPD was a respiratory disease. A total of 2.4% of subjects had been diagnosed with COPD and received treatment. Television was the most common source of information about COPD, with 57.1% of the subjects receiving information in this way. After being informed about COPD, smoking-cessation willingness increased in 84.1% of the study group. It increased in 86.3% of the subjects without awareness of COPD and in 81.2% of subjects with COPD-related symptoms. CONCLUSION: We found that awareness of COPD is very poor among current smokers in Korea. Many smokers perceived their health status as good, despite the presence of COPD-related symptoms. As the level of smoking-cessation willingness was different between those with and without awareness of COPD or COPD-related symptoms, a personalized education program with various educational tools may be needed to enhance awareness of the disease and to motivate smokers to quit.
Adult
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Aged
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Aged, 80 and over
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Asian Continental Ancestry Group/psychology
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*Awareness
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Female
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*Health Knowledge, Attitudes, Practice
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Health Status
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Health Surveys
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Humans
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Interviews as Topic
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Male
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Middle Aged
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Motivation
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*Pulmonary Disease, Chronic Obstructive/diagnosis/etiology/prevention & control
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Questionnaires
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Republic of Korea
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Risk Factors
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Smoking/*adverse effects/epidemiology
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Smoking Cessation
8.Awareness of chronic obstructive pulmonary disease in current smokers: a nationwide survey.
So Yeong MUN ; Yong Il HWANG ; Joo Hee KIM ; Sunghoon PARK ; Seung Hun JANG ; Jae Yong SEO ; Ja Kyung KIM ; Yong Bum PARK ; Jae Jung SHIM ; Ki Suck JUNG
The Korean Journal of Internal Medicine 2015;30(2):191-197
BACKGROUND/AIMS: Cigarette smoking is the most common risk factor for chronic obstructive pulmonary disease (COPD). However, few studies of the attitudes toward COPD of smokers, the group at risk of developing this condition, have been conducted. The purpose of this study was to explore the awareness of and attitudes toward COPD of current smokers. METHODS: The sample consisted of 502 individuals aged 45 and older from throughout Korea who smoked at least 10 packs of cigarettes per year. Telephone interviews using a structured questionnaire were conducted with respondents. RESULTS: First, we evaluated the health status of subjects, finding that 45.4% considered themselves to be in good health. We also asked about COPD-related symptoms, and 60.6% of subjects reported such symptoms. However, only 1.2% of subjects had been diagnosed with or treated for COPD, only 0.4% spontaneously mentioned COPD as a respiratory disease, and only 26.5% recognized COPD as a respiratory disease after seeing a list of such diseases. Television ranked as the top source of information about COPD. The willingness of 45.0% of subjects to stop smoking increased after being informed about COPD. CONCLUSIONS: Despite having COPD-related symptoms, most smokers did not know that COPD is a respiratory disease. The attitudes of smokers toward COPD and smoking cessation varied according to socioeconomic status. In summary, a continuous effort to increase the awareness of COPD among smokers is needed. Additionally, strategies tailored according to different socioeconomic groups will also be necessary.
Aged
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Asian Continental Ancestry Group/*psychology
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*Awareness
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Consumer Health Information
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Cross-Sectional Studies
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Female
;
Health Knowledge, Attitudes, Practice/*ethnology
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Health Promotion
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Health Status
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Health Surveys
;
Humans
;
Male
;
Mass Media
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Middle Aged
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Patient Compliance/ethnology
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Pulmonary Disease, Chronic Obstructive/diagnosis/*ethnology/psychology/therapy
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Republic of Korea/epidemiology
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Risk Factors
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Risk Reduction Behavior
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Smoking/*adverse effects/*ethnology/prevention & control/psychology
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Smoking Cessation/ethnology
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Socioeconomic Factors
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Surveys and Questionnaires
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Time Factors
9.The application of "preventive treatment theory" in chronic airway inflammatory disease.
Jing-Cheng DONG ; Bao-Jun LIU ; Hong-Ying ZHANG
Chinese Journal of Integrated Traditional and Western Medicine 2013;33(7):983-989
Bronchial asthma and chronic obstructive pulmonary disease (COPD), as chronic airway inflammatory diseases, seriously threaten the health of human beings. Chinese medicine has obvious advantages in prevention and treatment of them. "Preventive treatment theory" is a sort summarization of preventive medicine in Chinese medicine. The theory is not only reflected at the disease prevention levels, also embodied in the active treatment and the rehabilitation process. It was especially deep and colorfully embodied in the prevention and treatment of chronic airway inflammatory diseases such as asthma and COPD. In this paper,clarified were the prevention and treatment targets, ways of thinking and methods in different stages of asthma and COPD from various viewpoints including prevention before disease occurrence, treating disease at disease onset, preventing the aggravation once disease occurs, and consolidation after disease occurs. We hope to improve ways of thinking and prevention and treatment levels of bronchial asthma and COPD by Chinese medicine.
Asthma
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prevention & control
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Chronic Disease
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Humans
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Medicine, Chinese Traditional
;
methods
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Pulmonary Disease, Chronic Obstructive
;
prevention & control
10.Chronic Obstructive Pulmonary Disease in Korea: Prevalence, Risk Factors, and Quality of Life.
Journal of Korean Academy of Nursing 2011;41(2):149-156
PURPOSE: This study seeks to examine prevalence, risk factors, and quality of life of Korean adults with Chronic Obstructive Pulmonary Disease (COPD). METHODS: From the database of the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV-1, 2008), the researchers selected 1,458 adults over the age of 45. The original study was a population-based epidemiological survey of health and nutrition with a stratified multistage clustered probability design. Prevalence of COPD was computed on the basis of the sampling weight. Data were analyzed using descriptive statistics, chi2 test, t-test and multiple logistic regression with the SPSS WIN 18.0 and SAS Ver. 9.1 program. RESULTS: The prevalence of COPD was 18.0% among people older than 45 yr. The prevalence of current smokers was 19.7% in this population and 26.3% in individuals with COPD. Age, gender, education, and smoking levels were found to be risk factors for COPD. Significant difference in quality of life was founded between adults with COPD and the healthy controls. CONCLUSION: The results of this study indicate that COPD is a highly prevalent disease in Korea. To reduce the prevalence of COPD and improve health-related quality of life in patients with COPD, nursing interventions must focus on prevention of risk factors.
Age Factors
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Aged
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Databases, Factual
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Female
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Humans
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Male
;
Middle Aged
;
Odds Ratio
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Prevalence
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Pulmonary Disease, Chronic Obstructive/*epidemiology/pathology/prevention & control
;
Quality of Life
;
Questionnaires
;
Republic of Korea/epidemiology
;
Risk Factors
;
Sex Factors
;
Smoking

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