1.Research the epidemiology of chronic obstructive pulmonary disease in the population of Bac Giang city
Anh Van Le ; Chau Quy Ngo ; Hoi Thanh Nguyen ; Ngoc Thi Ngo ; Giap Van Vu
Journal of Medical Research 2007;53(5):87-93
Background: Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States, and is projected to rank fifth in 2020 in burden of disease caused worldwide. Objective: To research the epidemiology of COPD in the population of Bac Giang city and finding out the risk factors of COPD. Subjects and method: Cross-sectional survey of general population sample of 2,104 men and women with the age \ufffd?0 years in 30 wards of 11 communes of Bac Giang city. Data on respiratory symptoms, diseases, and risk factors were collected. Lung function tests were performed with Spiroanalyzer snoo, Japan. Results and conclusions: The incidence of COPD was 2.3%; in men 3.0% and in women 1.7%. The incidence of simple chronic bronchitis was 6.4%. People who smoked had higher rate of COPD than the others (OR = 2.8). The incidence of smoking in COPD was 55.9%. The three most important risk factors of COPD was the age \ufffd?0; smoking >15 pack/year and medical history of asthma.
Pulmonary Disease
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Chronic Obstructive/ epidemiology
2.Epidemiology of Chronic Obstructive Pulmonary Disease.
Tuberculosis and Respiratory Diseases 2003;55(4):333-343
No abstract available.
Epidemiology*
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Pulmonary Disease, Chronic Obstructive*
3.Status of chronic obstructive lung disease at department of respiratory of Bach Mai hospital on five years (1996-2000)
Journal of Medical Research 2003;21(1):35-39
3606 inpatients at the Department of Pneumology of Bach Mai Hospital from 1 Jan 1996 to 31 Dec 2000 were studied retrospectively. 904 patients accquired COPD, ie in the first rank, among them 142 with the chronical cardio-pulmonary complication male/female ratio was 2.13, age above 50 was 81.6%; 275/299 have had the smoking habit. The common symptoms were cough with sputum 80.75%, dyspnea 78.65%, rale 42%. 238 patients underwent an exam of ventilation function with FEV1 56.5 27.35% in comparing with theorical value, FEV1/FVC = 64 24.55%. 10/89 patients had FEV1/FVC > 75% but Tiffeneau index FEV1/VC < 70%. Average duration of hospital days was 12.9 days.
Pulmonary Disease, Chronic Obstructive
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disease
;
epidemiology
4.Reflux esophagitis is one of highly prevalent comorbidities among patients with chronic obstructive pulmonary disease.
The Korean Journal of Internal Medicine 2014;29(4):428-429
No abstract available.
Esophagitis, Peptic/*epidemiology
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Female
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Humans
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Male
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Pulmonary Disease, Chronic Obstructive/*epidemiology
6.A study on the methodology regarding the prevalence survey of chronic obstructive pulmonary disease in China.
Yu-Min ZHOU ; Sheng-Ming LIU ; Jia-Chun LV ; Jin-Peng ZHENG ; Na-Shan ZHONG ; Pi-Xin RAN
Chinese Journal of Epidemiology 2006;27(9):814-818
OBJECTIVETo explore the methodology on prevalence study of chronic obstructive pulmonary disease (COPD) in line with the world, to obtain accurate epidemic data of COPD in China.
METHODSA national multi-center cross-sectional survey on prevalence, risk factors and burden of COPD was conducted in China. In each area, a population-based cluster sample of approximately 1450 individuals aged 40 years or older was interviewed, using standardized questionnaires that were revised on the methodology of burden of lung diseases (BOLD) study and according under the context of China. All participants were submitted to pre-bronchodilator spirometry. Those with airflow limitation received post-bronchodilator spirometry, physical examination, X-rays of chest and EKG (electrocardiogram) tests. The post-bronchodialators FEV1/FVC < 70% was identified as having COPD.
RESULTSInvestigation has been completed with the same standardized procedures by all sites, up to the requirement of quality control. Over 85.0% of the spirometry tests and 95.0% of questionnaires had met the criteria of quality control in each area. Overall, 95.2% of the data was valid with acceptable spirometry and questionaire, and the valid response rate was 79.0%.
CONCLUSIONThe protocol was in line with the international standards, by which the prevalence of COPD in China was of adequate quality and valid.
Adult ; China ; epidemiology ; Epidemiologic Studies ; Humans ; Prevalence ; Pulmonary Disease, Chronic Obstructive ; epidemiology
7.Disease burden of chronic obstructive pulmonary diseases in west rural areas of China, 2004 - 2005.
Xiao-qian SHI ; Nan HU ; Xiao-yan LI ; Zheng-jing HUANG ; Yong JIANG ; Wen-hua ZHAO
Chinese Journal of Preventive Medicine 2011;45(1):68-72
OBJECTIVETo study the death burden of chronic obstructive pulmonary diseases (COPD) in west rural areas of China in 2004 - 2005.
METHODSThe data from 2004 - 2005 the Third National Mortality Retrospective Sampling Survey were used in the study. A total of 28 621 276 person years were investigated in west rural areas, which covered 12 provinces, and consisted of 42 surveillance districts. Based on the data of death cause and population, mortality of COPD, years of potential life lost(YPLL) rate, working YPLL (WYPLL) rate, YPLL rate due to COPD/YPLL rate due to all deaths in west rural areas were calculated and compared with other rural areas. Standardized death rate, standardized YPLL (SYPLL) rate, standardized working YPLL (SWYPLL) rate were calculated from census data in 2000 as standard population and 2004 - 2005 national life expectancy as standard life expectancy.
RESULTSThe elder has the higher crude death rate and YPLL rate of COPD in survey districts of west rural areas. And the crude death rate of COPD and YPLL rate were different in different genders. The YPLL rate was 15.47‰ in male and 15.73‰ in female. The crude death rate, YPLL rate, WYPLL rate, the ratio of YPLL rate due to COPD/YPLL rate due to all deaths in survey districts of west rural areas were: 109.53/100 000, 15.76‰, 2.82‰, 11.23%, which were high. While crude death rate, YPLL rate, WYPLL rate, the ratio of YPLL rate due to COPD/YPLL rate due to all deaths in the poorest survey districts of west rural areas were: 122.04/100 000, 27.47‰, 4.26‰, 13.44%, which were higher than other stratifications of west rural areas.
CONCLUSIONThe death burden of COPD in west rural areas in 2004 - 2005 was the heaviest one in China which experienced the feature that the poorer the rural regions, the heavier the death burden.
China ; epidemiology ; Cost of Illness ; Female ; Humans ; Male ; Pulmonary Disease, Chronic Obstructive ; economics ; epidemiology ; mortality ; Rural Population
8.Incidence of chronic obstructive pulmonary disease and risk factors in the Suzhou cohort.
Meng Shi YANG ; Xi Kang FAN ; Jian SU ; Hao YU ; Yan LU ; Yu Jie HUA ; Pei PEI ; Jun LYU ; Ran TAO ; Jin Yi ZHOU ; Ming WU
Chinese Journal of Epidemiology 2023;44(6):868-876
Objective: To understand the incidence of chronic obstructive pulmonary disease (COPD) in the Suzhou cohort, and explore the risk factors for the development of COPD in Suzhou, and provide a scientific basis for COPD prevention. Methods: This study was based on the China Kadoorie Biobank project in Wuzhong District, Suzhou. After excluding individuals with airflow obstruction and self-reported chronic bronchitis, emphysema, or pulmonary heart disease at baseline, 45 484 individuals were finally included in the analysis. Cox proportional risk models were used to analyze risk factors of COPD and calculate hazard ratios and 95% confidence interval (CI) in the Suzhou cohort. The effect modifications of smoking on the association between other risk factors and COPD were evaluated. Results: Complete follow-up was available through December 31, 2017. Participants were followed up for a median of 11.12 years, and 524 individuals were diagnosed with COPD during the follow-up period; the incidence was 105.54 per 100 000 person-years. Multivariate Cox proportional risk regression models showed that age (HR=3.78, 95%CI:3.32-4.30), former smoking (HR=2.00, 95%CI:1.24-3.22), current smoking (<10 cigarettes/day, HR=2.14, 95%CI:1.36-3.35;≥10 cigarettes/day, HR=2.69, 95%CI:1.60-4.54), history of respiratory disease (HR=2.08, 95%CI:1.33-3.26), daily sleep duration ≥10 hours (HR=1.41, 95%CI:1.02-1.95) were associated with increased risk of COPD. However, education level of primary school and above (primary or junior high school, HR=0.65, 95%CI:0.52-0.81; high school and above, HR=0.54, 95%CI:0.33-0.87), consuming fresh fruit daily (HR=0.59, 95%CI:0.42-0.83) and consuming spicy food weekly (HR=0.71, 95%CI:0.53-0.94) were associated with reduced risk of COPD. Conclusions: The incidence of COPD is low in Suzhou. Older age, smoking, history of respiratory disease, and long sleep duration were risk factors for the development of COPD in the Suzhou cohort.
Humans
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Incidence
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Pulmonary Disease, Chronic Obstructive/epidemiology*
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Risk Factors
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Smoking/epidemiology*
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Tobacco Smoking
9.Does the 2017 global initiative for chronic obstructive lung disease revision really improve the assessment of Chinese chronic obstructive pulmonary disease patients? A multicenter prospective study for more than 5 years.
Yanan CUI ; Yiming MA ; Zhongshang DAI ; Yingjiao LONG ; Yan CHEN
Chinese Medical Journal 2023;136(21):2587-2595
BACKGROUND:
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 proposed a new classification that reclassified many chronic obstructive pulmonary disease (COPD) patients from group D to B. However, there is a paucity of data related to the comparison between reclassified and non-reclassified COPD patients in terms of long-term prognosis. This study aimed to investigate long-term outcomes of them and determine whether the GOLD 2017 revision improved the assessment of COPD patients.
METHODS:
This observational, multicenter, prospective study recruited outpatients at 12 tertiary hospitals in China from November 2016 to February 2018 and followed them up until February 2022. All enrolled patients were classified into groups A to D based on GOLD 2017, and the subjects in group B included patients reclassified from group D to B (group DB) and those remaining in group B (group BB). Incidence rates and hazard ratios (HRs) were calculated for the exacerbation of COPD and hospitalization in each group.
RESULTS:
We included and followed up 845 patients. During the first year of follow-up, the GOLD 2017 classification had a better discrimination ability for different risks of COPD exacerbation and hospitalization than GOLD 2013. Group DB was associated with a higher risk of moderate-to-severe exacerbation (HR = 1.88, 95% confidence interval [CI] = 1.37-2.59, P <0.001) and hospitalization for COPD exacerbation (HR = 2.23, 95% CI = 1.29-3.85, P = 0.004) than group BB. However, during the last year of follow-up, the differences in the risks of frequent exacerbations and hospitalizations between group DB and BB were not statistically significant (frequent exacerbations: HR = 1.02, 95% CI = 0.51-2.03, P = 0.955; frequent hospitalizations: HR = 1.66, 95% CI = 0.58-4.78, P = 0.348). The mortality rates of the two groups were both approximately 9.0% during the entire follow-up period.
CONCLUSIONS
The long-term prognosis of patients reclassified into group B and of those remaining in group B was similar, although patients reclassified from group D to group B had worse short-term outcomes. The GOLD 2017 revision could improve the assessment of Chinese COPD patients in terms of long-term prognosis.
Humans
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Prospective Studies
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East Asian People
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Disease Progression
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Severity of Illness Index
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Pulmonary Disease, Chronic Obstructive/epidemiology*
10.Progress in research of chronic obstructive pulmonary disease and risk factors.
Jia Min WANG ; Chao WANG ; Gang LI
Chinese Journal of Epidemiology 2022;43(8):1343-1348
Chronic obstructive pulmonary disease (COPD) is a common, preventable and treatable chronic airway disease characterized by persistent airflow restriction and associated respiratory symptoms. COPD is the main cause of morbidity and mortality of chronic diseases and one of the top three causes of death in the world. The prevalence of COPD among provinces in China are at a high levels for years. The prevalence of COPD varies from country to country, region to region, and population to population, and the incidence and development of COPD are influenced by multi risk factors, including individual genetic factors, age, sex, body mass index, abdominal obesity and physical activity and environment factors, such as smoking, indoor and outdoor air pollution, and occupational exposure.
Air Pollution/adverse effects*
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Asthma/epidemiology*
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Humans
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Prevalence
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Pulmonary Disease, Chronic Obstructive/diagnosis*
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Risk Factors