Gastric cancer is one of the leading causes of cancer mortality in the world.The development and progression of gastric cancer is attributed to a number of genetic and epigenetic alterations of oncogene and tumor suppress gene.

The paper first expounds the concept and content of patients＇ right of privacy, introduces some law regulations of patients right of privacy in our countryand dicusses the legal character and the legal responsibility about the violation of patients＇ right of privacy, administrative legal responsibility and civil legal responsibility.

Blount disease is a common childhood condition that requires surgical correction. The conventional method of osteotomy and acute correction is associated with risk of neurovascular complications and occasionally displacement of the intra operative alignment. This case report describes a new technique that involves multiple longitudinal osteotomies over the proximal tibia without loss of cortical continuity between the proximal and distal tibia. It simulates an incomplete (greenstick) fracture that allows p
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Intellectual disability is a genetically heterogeneous disease,however,more than half of the genetic etiologies still remain unexplained.Since whole exome sequencing is applied for intellectual disability,a mature work flow has been established,which firstly discovered some important causative genes.This paper reviews the application,advantages and disadvantages of whole exome sequencing for sporadic,unexplained intellectual disability.

Objective:To investigate the role of HGF in myringoplasty.Methods:Fifty-nine cases of chronic tympanic membrane(TM) perforation were treated with hepatocyte growth fator(HGF) in myringoplasty.Results:According to the clinical observation,the average healing time after myringoplasty was 9 days.Side effect was not observed.Conclusion:The result showed that HGF could improve the healing of TM perforation.

Objective:To obtain the spike glycoprotein(S protein) of SARS coronavirus (SARS-Cov) for detection of the corresponding antibody and preparation of diagnostic kits.Methods:Genes encoding S protein were picked out to form a new gene and divided into two parts according to the prediction of antigenicty.They were obtained by nucleotide synthesis and were cloned into expression vector pET32a(+) respectively.Proteins then were induced by IPTG and purified through Ni-NTA.Results:Target proteins were successfully expressed and purified.Conclusion:The recombinant S proteins of SARS-CoV could be of great help in diagnosing the disease and investigating the virus further.

Objective:To find the clinical features and to provide the preventive and therapeutic methods by analyzing the disease spectrum and major death causes of in-patients.Methods:The clinical data of the elderly in-patients in urban and outskirt hospitals between1989 and 1998 were surveyed and analyzed retrospectively.Results:The cumulative data of ten years according to systems showed that diseases of digestive system ranked the first (21.1%),and the other systems ranking in order were respiratory system, cardiovascular system, nervous system and so on.Among the first ten common diseases chronic bronchitis and chronic obstructive emphysema (9.27%)ranked the first,and then other diseases ranking in order were cerebral vascular disease,coronary heart disease,cholelithiasis,essential hypertension,primary bronchogenic carcinoma of lung,diabetes mellitus,benign prostatic hyperplasia,chronic cor pulmonale,chronic gastritis and peptic ulcer.Of diseases ranked the first,which accounted for 1.56%,and then the other death causes ranking in order were gastro-intestinal disease,nervous system disease,cardiovascular disease,accidents and toxic damage etc.The death causes according to types ranked in order as follows.The first one was malignant tumor,its mortality being 1.22% in the elderly in-patient group.The following death causes ranking in order were cerebral vascular disease,chronic bronchitis and emphysema,coronary heart disease, etc.Conclusions:The common diseases of elderly patients ranking in order were diseases of digestive system,respiratory system,cardiovascular system,nervous system and so on.The major death causes of the elderly patients were diseases of respiratory system,cardiovascular system and malignant tumor.It is of importance for the aged to take preventive measures.It is suggested to do routine physical examination to detect and prevent risk factors of some diseases and change the improper living habits and strengthen the preventive and therapeutic methods.

Objective:To study the clinical significance of determining serum liver specific autoantibodies in HCV patients.Methods:Hep-2 cells,rat liver tissue,rat kidney tissue and rat stomach tissue as substrates forANA,ASMA,AMA and ALKM were detected by indirect immunofluorescence assay in the serum of 67 HCV patients,32 HAV patients,50 patients with other diseases and 30 normal subjects.Results:The positive rate of autoantibodies in HCV patients were 25.4%,and there was significant difference compared with the other 3 groups( P 0.05).Conclusion:HCV infection can induce autoimmune reactions resulting in production of autoantibodies and its titer is helpful for treatment of HCV patients.

[Objective] To investigate the treatment effect of primary trigeminal neuralgia by using xiao-chai-hu decoction combined with Carbamazepine. [Methods] 70 patients with primary trigeminal neuralgia treated in the department of internal medicine of our hospital from June 2011 to June 2012, and randomly divided into experimental group and control group, each group of 35 cases. Patients in the control group taking Carbamazepine; Patients in the experimental group taking Carbamazepine combined with xiao-chai-hu decoction.To observe the clinical efficacy and side effects in two groups after 1 month of treatment, doing statistical analysis. [Results] The experimental group and control group total effective rates were 85.71%, 62.86% repectively, there was statistical y significant difference; the patients in the experimental group after treatment, pain degree and adverse reaction rate were significantly lower than the control group, there were significant differences. [Conclusion] Carbamazepine combined with xiao-chai-hu decoction has good curative effect for primary trigeminal neuralgia, worthy of clinical application.

Objective To develop a fast medical air(including oxygen,negative pressure air and positive pressure air) concentrated supply system for field infirmary.Methods Designed in modularized type,three subsystems can be quickly united together.Results Medical air can be supplied for large quantities of the wounded and sick in field treatment.Conclusion The system guarantees the smooth treatment for patients in field infirmary.[Chinese Medical Equipment Journal,2008,29(2):69,75]