Gastric cancer is one of the leading causes of cancer mortality in the world.The development and progression of gastric cancer is attributed to a number of genetic and epigenetic alterations of oncogene and tumor suppress gene.

The paper first expounds the concept and content of patients＇ right of privacy, introduces some law regulations of patients right of privacy in our countryand dicusses the legal character and the legal responsibility about the violation of patients＇ right of privacy, administrative legal responsibility and civil legal responsibility.

Objective:As the main component of human capital, health capital's dynamic path has been generally received attention. Methods: According to Grossman’s theory of health capital, the health investment return is defined as the monetary benefits and psychological benefits and the optimum control theory is used to study the optimal path of health investment. Results:The optimum path of health investment has sole saddle point equilibrium with both stability and uniqueness. Conclusion: The maximum utility of consumers depends on the their subjective judgment of future life. As a rational consumer, it needs to consider that health risk rises with age gradually, health investment should be increased to maximize lifetime utility.

Structural fat grafting has been considered as a valid option for soft-tissue augmentation in cosmetic surgery.However,its result has often been considered poor or unpredictable and is largely surgeon dependent.Less desirable outcome after fat grafting is probably due to lack of good surgical technique.In order to help plastic surgeons to gain more insight to this valid fat grafting technique,the author conducted a critical review of the current literature in this subject.To better address the findings of the study,the fat grafting technique was arbitrarily classified into 4 essential steps to determine how the donor sites should be selected and how the fat grafts should be harvested,processed,and placed.It becomes clear that several basics in an established fat grafting technique have gained much of scientific support and should be followed in order to achieve an optimal outcome for our patients.These basics include the proper selection of donor sites,to harvest fat grafts with an atraumatic technique,to process fat grafts with centrifugation in an appropriate setting,and to place fat grafts with a unique fashion.

Preclinical toxicology of PsD-007(a new photosensitizer prepared in our coll-ege)was studied.Pathological observations were performed on major organs of the toxic dogs including liver, kidneys, myocardium, lungs, spleen, stomach, intestine, mesenteric lymph nodes, urinary bladder, prostata, testes, ovary, adrenals, pituitary gland, thyroid and brain.Focal balloning degeneration of hepatic cells occurred in lower dose groups, and degeneration and necrosis of hepatocytes and proximal convoluted tubular epithelial cells of kidney, and edema of brain in higher dose groups were observed in acute toxicity testing.The hepatocytes were normal, but hyperplasia, swelling and vacuoles within the cytoplasm of the Kupffers cells in liver, necrosis of tubules of kidney and edema of brain in higher dose groups were found in subacute testing. These damages were reversible within 4 weeks except in higher dose groups, and their morphologic severity was dose-related.The results show that the liver and kidney may be the main target organs of toxicity of PsD, and the detections of hepatic and renal functions may be useful to guard against its toxic effects during clinical use.

Objective:To investigate the effect of pridoxamine on erectile function in diabetic rats.Methods:Male adult Sprague-Dawley rats were induced for diabetes by an intraperitoneal injection of streptozotocin,then randomly divided into DM group and DM+PM group.The rats in DM+PM group were treated with pridoxamine at a dosage of 200mg/kg through a gastric perfusion every day.Twelve weeks later the erectile function of all these rats were evaluated,and their penises tissues were harvested.The NO,NOS,and cGMP levels in corpus cavernosum were measured.Results:The diabetic rat model was successfully established.The erectile function was much better in normal control group(group C,100%) and DM+PM group(71.4%)than in DM group(46.2%)(P

Objective To develop a fast medical air(including oxygen,negative pressure air and positive pressure air) concentrated supply system for field infirmary.Methods Designed in modularized type,three subsystems can be quickly united together.Results Medical air can be supplied for large quantities of the wounded and sick in field treatment.Conclusion The system guarantees the smooth treatment for patients in field infirmary.[Chinese Medical Equipment Journal,2008,29(2):69,75]

OBJECTIVE To explore the clinical distributed features and drug-resistant conditions of pathogenic bacteria in nosocomial infection in the last three years for the reference to clinical drug administration. METHODS Retrospective analysis was performed about drug-resistant conditions of pathogenic bacteria in nosocomial infection in the last three years from 2004 to 2006. RESULTS Totally 488 pathogenic strains, including 289 strains of Gram-negative bacteria (59.22%);95 strains of Gram-positive bacteria (19.47%) and 104 strains of fungi (21.31%),were isolated from patients in the last three years, the isolation rate of fungi,Acinetobacter baumannii and Enterobacter cloacae tended to increase year by year. They resisted to commonly used antibiotics at different degree, the rate of multiple-resistance was 80.33%. CONCLUSIONS Most pathogens isolated from patients with nosocomial infection are Gram-negative bacteria, which always display multi-resistant tendency to routine antimicrobial agents. The culture of pathogenic bacteria and rational use of antimicrobial agents should be emphasized to decrease the incidence of nosocomial infection, the factors which easily caused nosocomial infection should be reduced as well.

Objective:To obtain the spike glycoprotein(S protein) of SARS coronavirus (SARS-Cov) for detection of the corresponding antibody and preparation of diagnostic kits.Methods:Genes encoding S protein were picked out to form a new gene and divided into two parts according to the prediction of antigenicty.They were obtained by nucleotide synthesis and were cloned into expression vector pET32a(+) respectively.Proteins then were induced by IPTG and purified through Ni-NTA.Results:Target proteins were successfully expressed and purified.Conclusion:The recombinant S proteins of SARS-CoV could be of great help in diagnosing the disease and investigating the virus further.

Objective:To find the clinical features and to provide the preventive and therapeutic methods by analyzing the disease spectrum and major death causes of in-patients.Methods:The clinical data of the elderly in-patients in urban and outskirt hospitals between1989 and 1998 were surveyed and analyzed retrospectively.Results:The cumulative data of ten years according to systems showed that diseases of digestive system ranked the first (21.1%),and the other systems ranking in order were respiratory system, cardiovascular system, nervous system and so on.Among the first ten common diseases chronic bronchitis and chronic obstructive emphysema (9.27%)ranked the first,and then other diseases ranking in order were cerebral vascular disease,coronary heart disease,cholelithiasis,essential hypertension,primary bronchogenic carcinoma of lung,diabetes mellitus,benign prostatic hyperplasia,chronic cor pulmonale,chronic gastritis and peptic ulcer.Of diseases ranked the first,which accounted for 1.56%,and then the other death causes ranking in order were gastro-intestinal disease,nervous system disease,cardiovascular disease,accidents and toxic damage etc.The death causes according to types ranked in order as follows.The first one was malignant tumor,its mortality being 1.22% in the elderly in-patient group.The following death causes ranking in order were cerebral vascular disease,chronic bronchitis and emphysema,coronary heart disease, etc.Conclusions:The common diseases of elderly patients ranking in order were diseases of digestive system,respiratory system,cardiovascular system,nervous system and so on.The major death causes of the elderly patients were diseases of respiratory system,cardiovascular system and malignant tumor.It is of importance for the aged to take preventive measures.It is suggested to do routine physical examination to detect and prevent risk factors of some diseases and change the improper living habits and strengthen the preventive and therapeutic methods.