A prostatic abscess is a rare, but potentially serious disease. The mainstay of treatment for the prostatic abscess is antibiotic administration and drainage. Here, we experienced a 66-year-old man with a prostatic abscess caused by Providencia rettgeri, which has not been reported as a pathogenic agent of a prostatic abscess. He was cured using antibiotics, without surgical drainage. This case suggests that the appropriate selection of patients for antibiotic therapy may provide an excellent prognosis.
Abscess ; Anti-Bacterial Agents ; Drainage ; Humans ; Prognosis ; Prostate ; Providencia

High cholesterol is one of the important factors inducing cardiovascular and cerebrovascular diseases. Drug therapy is the main method for reducing cholesterol, but has the disadvantages such as high cost and side effects. Studies have shown that intestinal bacteria play important roles in cholesterol metabolism. However, there are few reports on the screening and functional evaluation of cholesterol-lowering intestinal bacteria. In this study, 36 bile-tolerant bacteria were screened from healthy people stool through culturomics using bovine bile acid or artificial mixed bile acids as substrates. Taking Lactobacillus rhamnosus GG (LGG) as a positive control, three bile acid concentration groups (0 g/L, 0.3 g/L, 3 g/L) were set up to evaluate the cholesterol-lowering ability of bile-tolerant bacteria in vitro. Ten bacteria (including Proteus mirabilis, Providencia stuartii, Proteus vulgaris et al) were identified as the dominant cholesterol-lowering bacteria. Six of the above bacteria, Proteus mirabilis, Providencia stuartii, Proteus vulgaris, Proteus penneri, Wohlfahrtiimonas chitiniclastica, Providencia rettger, were evaluated for their ability to reduce triglycerides in vitro and tolerance to artificial gastric juice. Comparing with strain LGG, the six bacteria showed better triglyceride-lowering ability in vitro. With the decrease of pH value of artificial gastric juice and the increase of treatment time, the survival rate of six bacteria decreased. The above screening experiments and functional evaluation provide a basis for further development of potential cholesterol-lowering bacterial products.
Animals ; Cattle ; Cholesterol ; Gammaproteobacteria ; Humans ; Proteus mirabilis ; Providencia

Providencia stuartii is occasionally isolated from patients with chronic otitis media, however it has not been reported as a cause of acute otitis media so far. We recently isolated P. stuartii from the pus specimen of right middle ear of a 2-year-old patient with acute otitis media. The patient was admitted because of right-sided otorrhea for 2 weeks. The symptom was not relieved by first-line empirical antibiotics (amoxicillin-clavulanic acid and netilmicin), but it was subsided dramatically with the changed antibiotics (ceftriaxone and amikacin); the isolate was susceptible to these two antibiotics in in vitro susceptibility testing. To our knowledge, this is the first case report of acute otitis media caused by P. stuartii.
Anti-Bacterial Agents ; Child, Preschool ; Ear, Middle ; Humans ; Otitis Media* ; Otitis* ; Providencia* ; Suppuration

No abstract available.
Bacteremia/*microbiology ; Cross Infection/*microbiology ; Enterobacteriaceae Infections/*microbiology ; Female ; Humans ; Male ; Providencia/*isolation & purification ; *Tertiary Care Centers

BACKGROUND: Infections due to antimicrobial resistant bacteria pose serious problem in the care of the patients in intensive care units, oncology and hematology. It was to determine the prevalent species and cefpirome susceptibilities of the current isolates from these patients. METHODS: Bacteria isolated from patients in the intensive care units, oncology and hematology in a fertiary care university hospital in 1997 were analyzed for the prevalent species. Antimicrobial susceptibility of the strains, most of which were isolated in 1997, was tested by the NCCLS agar dilution method. RESULTS: The proportion of potential pathogens isolated were: Staphylococcus aureus 16.1%, Acinetobacter baumannii 13.6%, Enterobacter-Serratia-Citrobacter group 12.1%, Enterococcus spp. 11.0% and Pseudomonas aeruginosa 10.4%. The lowest resistance rates were : A.baumannii to ampicillin/sulbactam (38%), P. aeruginosa to ceftazidime (37%), Providencia spp. to ceftriaxone (7%), S. marcescens to ceftazidime and cefpirome (10%), and E. coli (3%), K. pneumoniae (10%), E. cloacae (17%) and C. freundii (7%) to cefpirome. All isolates of penicillin-resistant Streptococcus pneumoniae were susceptible to cefpirome. CONCLUSION: The in vitro test suggests that cefpirome should be more useful than the other generations of cephalosporins for the treatment of various nosocomial infections including those due to the 3rd generation cephalosporin-resistant E. cloacae, S. marcescens, C. freundii and penicillin-resistant S. pneumoniae.
Acinetobacter baumannii ; Agar ; Bacteria* ; Ceftazidime ; Ceftriaxone ; Cephalosporins ; Cloaca ; Cross Infection ; Enterococcus ; Family Characteristics ; Hematology* ; Humans ; Intensive Care Units ; Pneumonia ; Providencia ; Pseudomonas aeruginosa ; Staphylococcus aureus ; Streptococcus pneumoniae

We report a suspicious case of spontaneous bacterial peritonitis (SBP) caused by Providencia rettgeri and Clostridium perfringens in a patient with alcoholic cirrhosis. The patient presented with altered mentality and was taken to the emergency room. He was diagnosed with SBP after abdominal paracentesis and computed tomography and was treated with ceftriaxone and metronidazole. The pathogens were identified under suspicion of polymicrobial infection because of Gram-staining discrepancies between broth from blood culture bottles and colonies on solid media. He died of septic shock despite transfer to the intensive care unit. Although we could not conclude which organism had the leading role in this case of SBP and septicemia, we did verify the importance of Gram staining in a microbiology laboratory in terms of quality assurance.
Ceftriaxone ; Clostridium perfringens* ; Coinfection ; Emergency Service, Hospital ; Humans ; Intensive Care Units ; Liver Cirrhosis, Alcoholic ; Metronidazole ; Paracentesis ; Peritonitis* ; Providencia* ; Sepsis* ; Shock, Septic

BACKGROUND: In clinical microbiology the accurate and rapid identification of members of the family Enterobacteriaceae is essential for diagnostic and therapeutic purposes and for epidemiologic studies. Accuracy of identification system depends mainly on data base such as positive rate of biochemical reactions, relative frequency of occurrence of biotype, and isolation frequency of microorganisms. The purpose of this study was to analyze the isolation rate and biotype frequency of the family Enterobacteriaceae isolated from tertiary care hospital in Korea. METHODS: Isolation frequency of the family Enterobacteriaceae isolated from clinical specimens during the period of January 1998 to June 1998 were analyzed. And biochemical phenotypes of 2,022 isolates tested by 10 tube system consisting of 14 conventional biochemical tests were also analyzed. RESULTS: Isolation rate of the family Enterobacteriaceae to the genus level in order of decreasing frequency were Escherichia (37.0%), Serratia (15.9%), Klebsiella (14.9%), Enterobacter (11.1%), Providencia (8.1%), Citrobacter (2.8%), Proteus (2.5%), Morganella (2.4%), Salmonella (2.4%), and Cedecea (0.7%). Among the genus of the family Enterobacteriaceae, Budvicia, Edwardsiella, Ewingella, Hafnia, Kluyvera, Leminorella, Moellerella, Shigella, Tatumella, Xenorhabdus, Yersinia, and Yokenella were not isolated. The number of species and genus of the family Enterobacteriaceae by this study were 48 and 12, respectively. Over 95% of all clinical isolates belonged to only 25 species. CONCLUSIONS: Although these data about frequency of relative isolation rate and biotype patterns of the family Enterobacteriaceae is inadequate according to species and genus, yet these data will be utilized for the application and development of identification method of the family Enterobacteriaceae.
Citrobacter ; Edwardsiella ; Enterobacter ; Enterobacteriaceae* ; Escherichia ; Hafnia ; Humans ; Klebsiella ; Kluyvera ; Korea ; Morganella ; Phenotype ; Proteus ; Providencia ; Salmonella ; Serratia ; Shigella ; Tertiary Healthcare ; Xenorhabdus ; Yersinia

Providencia rettgeri is a member of Enterobacteriacea that is known to cause urinary tract infection (UTI), septicemia, and wound infections, especially in immunocompromised patients and in those with indwelling urinary catheters. We experienced a case of UTI sepsis by Providencia rettgeri in a patient with spinal cord injury. The patient had only high fever without urinary symptoms or signs after high dose intravenous methylprednisolone. The laboratory results showed leukocytosis (21,900/microL, segmented neutrophils 91.1%) and pyuria. Cefepime was given empirically and it was switched to oral trimethoprim-sulfamethoxazole because P. rettgeri was identified from blood and urine culture which was susceptible to TMP-SMX. The patient was improved clinically but P. rettgeri was not eradicated microbiologically. To the best of our knowledge, this is the first case report on sepsis caused by Providencia rettgeri in Korea.
Cephalosporins ; Fever ; Humans ; Immunocompromised Host ; Korea ; Leukocytosis ; Methylprednisolone ; Neutrophils ; Providencia ; Pyuria ; Sepsis ; Spinal Cord Injuries ; Trimethoprim, Sulfamethoxazole Drug Combination ; Urinary Catheters ; Urinary Tract Infections ; Wound Infection

BACKGROUND AND OBJECTIVES: It is important to know the current trend of resistance rate and species of pathogens in order to select appropriate antibiotics in the management of chronic suppurative otitis media. The purpose of this study is to investigate the current bacteriology of chronic supprative otitis media. SUBJECTS AND METHOD: A retrospective study was performed on the bacteriologic results of 169 out-patients of chronic otitis media with otorrhea who visited the department of otolaryngology at the Kyung Hee Medical Center from Jan 2000 to Dec 2002. RESULTS: The most common pathogenic organisms were Staphylococcus, Pseudomonas, Proteus and Providencia. The prevalence of MRSA was found to be 61.0 per cent of isolated Staphylococcus aureus. CONCLUSION: We investigated the current bacteriology of chronic suppurative otitis media and could not find remarkable changes in comparison with the results reported recently. Continuous and periodic studies on bacteriology and sensitivity tests should be performed for effective treatment of chronic suppurative otitis media.
Anti-Bacterial Agents ; Bacteriology* ; Humans ; Methicillin-Resistant Staphylococcus aureus ; Otitis Media ; Otitis Media, Suppurative* ; Otolaryngology ; Outpatients ; Prevalence ; Proteus ; Providencia ; Pseudomonas ; Retrospective Studies ; Staphylococcus ; Staphylococcus aureus

BACKGROUND: Chronic suppurative otitis media is one of the most common disease in the otolaryngologic field. It is important to choose of antibiotics in the management of chronic suppurative otitis media. OBJECTIVES: Bacteriologic studies can make it possible to use appropriate antibiotics. MATERIALS AND METHODS: The bacteriologic study was made on 98 cases of chronic suppurative otitis media who visited the department of otolaryngology, Dae Dong Hospital in Pusan from Nov. 1989 to Dec. 1995 and the following results were obtained. RESULTS: 1) In 90 cases in which pathogenic organism was isolated, single infection was 81 cases(90%) and mixed infection was 9 cases(10%). 2) The most frequent pathogenic organism was Staphylococcus(46.5%) and Proteus(16.1%), Pseudomonas(14.1%), Providencia(10.1%) were the next. 3) In the aspect of the sensitivity to antibiotics, Ciprofloxacin, Ceftriaxon and Amikacin were sensitive drug generally. 4) Staphylococcus was sensitive to Vancomycin and Ciprofloxacin. 5) Proteus was sensitive to Amikacin, Ciprofloxacin, and Ceftriaxon. 6) Pseudomonas was sensitive to Ciprofloxacin, Amikacin and Piperacin. 7) Providencia was sensitive to Ciprofloxacin, Ceftriaxon, Amikacin and Piperacin. 8) Methicillin Resistant Staphylococcus Aureus(MRSA) was 19 Strains(45.5%). CONCLUSION: Recently, pathologic strain and it's sensitivity to antibiotics has changed. So, we recommand that periodic bacteriologic study and sensitivity test should be done for effective management of chronic otitis media.
Amikacin ; Anti-Bacterial Agents ; Bacteriology ; Busan ; Ceftriaxone ; Ciprofloxacin ; Coinfection ; Methicillin Resistance ; Otitis Media ; Otitis Media, Suppurative* ; Otolaryngology ; Proteus ; Providencia ; Pseudomonas ; Staphylococcus ; Vancomycin