1.Anomalous Bilateral Communication between the Inferior Alveolar Nerve and the Auriculotemporal Nerve: A Rare Variation
Nikha Bhardwaj ; Priya Sahni ; Abhishek Singhvi ; Meghanand Nayak ; Vineeta Tiwari
Malaysian Journal of Medical Sciences 2014;21(5):71-74
Branches of the posterior division of the mandibular nerve show various anomalous communications in the infratemporal region. Understanding such communication has relevance in the management of neuropathies and surgical procedures in this region. This study was conducted to explore such communicating branches, anticipating that they might provide information of clinical significance. A total of 15 human cadavers (30 infratemporal regions) were studied to explore such communicating branches in infratemporal region. The branches of the posterior division of the mandibular nerve were carefully dissected, and these branches were studied and analysed for any abnormal course. In one case, a rare type of bilateral communication between the auriculotemporal nerve and the inferior alveolar nerve, forming a loop with no association with any structure, was observed. It is possible that such communicating branches may be associated with delayed regression of the first arch vessels. The clinical implications of these anomalous communications require further detailed study for improved management of neuropathies and surgical procedures.
2.Flavonoids as therapeutics for myocardial ischemia-reperfusion injury: a comprehensive review on preclinical studies
Vipin Kumar VERMA ; Priya BHARDWAJ ; Vaishali PRAJAPATI ; Avantika BHATIA ; Sayani PURKAIT ; Dharamvir Singh ARYA
Laboratory Animal Research 2024;40(3):292-306
Ischemic heart disease is the most prevalent cause of death worldwide affecting both the gender of all age groups.The high mortality rate is due to damage of myocardial tissue that emanates at the time of myocardial ischemia and re-oxygenation, thus averting reperfusion injury is recognized as a potential way to reduce acute cardiac injury and subsequent mortality. Flavonoids are polyphenol derivatives of plant origin and empirical shreds of evidence substantiate their numerous activities such as antioxidant, anti-inflammatory, anti-apoptotic, and anti-thrombotic activity, leading to their role in cardio protection. Recent investigations have unveiled the capacity of flavonoids to impede pivotal regulatory enzymes, signaling molecules, and transcription factors that orchestrate the mediators participating in the inflammatory cascade. The present comprehensive review, dwells on the preclinical studies on the effectiveness of flavonoids from the year 2007 to 2023, for the prevention and therapeutics for myocardial ischemia-reperfusion injury.
3.Flavonoids as therapeutics for myocardial ischemia-reperfusion injury: a comprehensive review on preclinical studies
Vipin Kumar VERMA ; Priya BHARDWAJ ; Vaishali PRAJAPATI ; Avantika BHATIA ; Sayani PURKAIT ; Dharamvir Singh ARYA
Laboratory Animal Research 2024;40(3):292-306
Ischemic heart disease is the most prevalent cause of death worldwide affecting both the gender of all age groups.The high mortality rate is due to damage of myocardial tissue that emanates at the time of myocardial ischemia and re-oxygenation, thus averting reperfusion injury is recognized as a potential way to reduce acute cardiac injury and subsequent mortality. Flavonoids are polyphenol derivatives of plant origin and empirical shreds of evidence substantiate their numerous activities such as antioxidant, anti-inflammatory, anti-apoptotic, and anti-thrombotic activity, leading to their role in cardio protection. Recent investigations have unveiled the capacity of flavonoids to impede pivotal regulatory enzymes, signaling molecules, and transcription factors that orchestrate the mediators participating in the inflammatory cascade. The present comprehensive review, dwells on the preclinical studies on the effectiveness of flavonoids from the year 2007 to 2023, for the prevention and therapeutics for myocardial ischemia-reperfusion injury.
4.Flavonoids as therapeutics for myocardial ischemia-reperfusion injury: a comprehensive review on preclinical studies
Vipin Kumar VERMA ; Priya BHARDWAJ ; Vaishali PRAJAPATI ; Avantika BHATIA ; Sayani PURKAIT ; Dharamvir Singh ARYA
Laboratory Animal Research 2024;40(3):292-306
Ischemic heart disease is the most prevalent cause of death worldwide affecting both the gender of all age groups.The high mortality rate is due to damage of myocardial tissue that emanates at the time of myocardial ischemia and re-oxygenation, thus averting reperfusion injury is recognized as a potential way to reduce acute cardiac injury and subsequent mortality. Flavonoids are polyphenol derivatives of plant origin and empirical shreds of evidence substantiate their numerous activities such as antioxidant, anti-inflammatory, anti-apoptotic, and anti-thrombotic activity, leading to their role in cardio protection. Recent investigations have unveiled the capacity of flavonoids to impede pivotal regulatory enzymes, signaling molecules, and transcription factors that orchestrate the mediators participating in the inflammatory cascade. The present comprehensive review, dwells on the preclinical studies on the effectiveness of flavonoids from the year 2007 to 2023, for the prevention and therapeutics for myocardial ischemia-reperfusion injury.
5.Flavonoids as therapeutics for myocardial ischemia-reperfusion injury: a comprehensive review on preclinical studies
Vipin Kumar VERMA ; Priya BHARDWAJ ; Vaishali PRAJAPATI ; Avantika BHATIA ; Sayani PURKAIT ; Dharamvir Singh ARYA
Laboratory Animal Research 2024;40(3):292-306
Ischemic heart disease is the most prevalent cause of death worldwide affecting both the gender of all age groups.The high mortality rate is due to damage of myocardial tissue that emanates at the time of myocardial ischemia and re-oxygenation, thus averting reperfusion injury is recognized as a potential way to reduce acute cardiac injury and subsequent mortality. Flavonoids are polyphenol derivatives of plant origin and empirical shreds of evidence substantiate their numerous activities such as antioxidant, anti-inflammatory, anti-apoptotic, and anti-thrombotic activity, leading to their role in cardio protection. Recent investigations have unveiled the capacity of flavonoids to impede pivotal regulatory enzymes, signaling molecules, and transcription factors that orchestrate the mediators participating in the inflammatory cascade. The present comprehensive review, dwells on the preclinical studies on the effectiveness of flavonoids from the year 2007 to 2023, for the prevention and therapeutics for myocardial ischemia-reperfusion injury.